Aqueous alcoholic microbicidal compositions comprising zinc ions
Treatment compositions which impart a microbicidal benefit to treated surfaces which compositions comprise (or in certain preferred embodiments may consist essentially of, or may consist of) as constituents: a zinc source material which releases zinc ions into the treatment composition, preferably a source of Zn ++ ions; at least one lower alkyl monohydric alcohol (preferably at least about 25% wt. of a lower alkyl monohydric alcohol); at least one quaternary ammonium compound which provides a microbicidal benefit; optionally one or more further optional constituents which impart one or more advantageous technical or aesthetic benefits to the compositions, including one or more detersive surfactants; wherein the composition has a pH of at least 5, wherein the surface treatment compositions are characterized in exhibiting a microbicidal benefit, especially preferably against poliovirus type 1 Sabin (“PV1”), when tested according to one or more of the following standardized test protocols: ASTM E1052 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension, or ASTM E1053 Standard Test Method to Assess Virucidal Activity of Chemicals Intended for Disinfection of Inanimate, Nonporous Environmental Surfaces, or European Standard Surface Test, EN13697, or AOAC Germicidal Spray Products as Disinfectant Test Method, AOAC Index, 17 th Ed. (2000) against one or more challenge microorganisms.
1. A transparent liquid, inanimate surface treatment composition which imparts virucidal benefit to inanimate surfaces treated with said composition which composition comprises:
a zinc source material which releases zinc ions into the treatment composition;
about 35% wt. to 50% wt. of at least one C 1 -C 6 alkyl aliphatic monohydric alcohol,
at least one quaternary ammonium compound;
water;
optionally, one or more detersive surfactants;
optionally, one or more further constituents which impart one or more advantageous technical or aesthetic benefits to the compositions;
wherein the composition has a pH of at about 7 to about 11,
wherein the surface treatment composition is characterized in exhibiting a reduction of at least 3 log 10 against poliovirus type 1 (Sabin) (“PV1”) according to ASTM E1052 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension.
2. A composition according to claim 1 which comprises at least 40% wt. to 50% wt., of at least one C 1 -C 6 alkyl aliphatic monohydric alcohol.
3. A composition according to claim 1 wherein ethanol is the predominant or is the sole C 1 -C 6 alkyl aliphatic monohydric alcohol present in the composition.
4. A liquid, inanimate surface treatment composition which imparts a virucidal benefit to surfaces treated with said composition which comprises:
a zinc source material which releases zinc ions into the treatment composition;
about 35% wt. to about 50% wt. of at least one C 1 -C 6 lower alkyl aliphatic monohydric alcohol,
at least one quaternary ammonium compound which provides a microbicidal benefit;
water;
at least one nonionic detersive surfactant;
optionally, one or more further constituents which impart one or more advantageous technical or aesthetic benefits to the compositions;
wherein the composition has a pH of between about 7 to 11,
wherein the surface treatment composition is characterized in exhibiting a reduction of at least 3 log 10 of poliovirus type 1 (Sabin) (“PV1”) according to ASTM E1052 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension.
5. A composition according to claim 4 , which satisfies at least one of Conditions C, D, E or F:
log 10 reduction of poliovirus
type 1 (Sabin) (“PV1”) when
% wt. of at
tested according to the
least one
standardized test protocol:
lower alkyl
ASTM E1052 Standard Test
Con-
aliphatic
Method for Efficacy of
di-
pH or pH
monohydric
Antimicrobial Agents against
tion
range
alcohol
Viruses in Suspension
C
9 ≦ pH < 9.5
≧35 and ≦50
at least 3.0
D
9.5 ≦ pH < 10
≧35 and ≦50
at least 3.33
E
10 ≦ pH <
≧40 and ≦49.9
at least 5.0
10.5
F
about 7 to
≧35 and ≦49.9
at least 5.0
10.5 ≦ pH.
6. A composition according to claim 4 , which concurrently satisfies at least Condition H:
log 10 reduction of poliovirus
type 1 (Sabin) (“PV1”) when
% wt. of at
tested according to the
least one
standardized test protocol:
lower alkyl
ASTM E1052 Standard Test
aliphatic
Method for Efficacy of
Condi-
monohydric
Antimicrobial Agents against
tion
alcohol
pH or pH range
Viruses in Suspension
H
≧35 and <40
≧9.05 and ≦9.50
at least 3.0.
7. A composition according to claim 1 , which composition comprises:
a zinc source material which releases zinc ions into the treatment composition;
at least 40% wt. to about 50% wt. of at least one C 1 -C 6 alkyl aliphatic monohydric alcohol,
at least one quaternary ammonium compound which provides a microbicidal benefit;
at least one detersive nonionic surfactant;
water;
optionally, one or more further constituents which impart one or more advantageous technical or aesthetic benefits to the compositions;
wherein the composition has a pH of at least 8.5 but less than 11,
wherein the surface treatment compositions are characterized in exhibiting at least a 3 log 10 reduction of polivirus type 1 Sabin when tested according to ASTM E1052 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension.
8. A composition according to claim 1 , in which the composition comprises:
a zinc source material which releases zinc ions into the treatment composition;
at least 35% wt. to about 50% wt. of at least one C 1 -C 6 alkyl aliphatic monohydric alcohol, and wherein
a) when compositions comprise 35% wt. to <45% wt. of at least one lower alkyl aliphatic monohydric alcohol, the pH of the compositions are ≧9.46 and <11;
b) when compositions comprise ≧45% wt. to ≦50% wt. of at least one lower alkyl aliphatic monohydric alcohol, the pH of the compositions are ≧9.46 and <11;
at least one quaternary ammonium compound which provides a microbicidal benefit;
water;
optionally but preferably at least one detersive surfactant;
optionally, one or more further constituents which impart one or more advantageous technical or aesthetic benefits to the compositions;
and,
wherein the surface treatment compositions are characterized in exhibiting at least a 3 log 10 result when tested against poliovirus type 1 (Sabin) (“PV1”) tested according to ASTM E1052 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension.
9. A method of controlling the incidence of poliovirus type 1 (Sabin) (“PV1”) the method comprising the step of:
contacting an inanimate surface which is in need of treatment or upon which the presence of poliovirus type 1 (Sabin) (“PV1”) are suspected or are known to be present, with an effective amount of a composition according to claim 1 to provide a microbicidal benefit to the contacted surface.
10. A composition according to claim 1 having a pH of at least about 8.
11. A composition according to claim 1 having a pH of at least about 8.5.
12. A composition according to claim 1 having a pH of at least about 9.
13. A composition according to claim 1 , which exhibits a reduction of at least 3.5 log 10 against poliovirus type 1 (Sabin) (“PV1”) according to ASTM E1052 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension.
14. A composition according to claim 13 , which exhibits a reduction of at least 4.0 log 10 against poliovirus type 1 (Sabin) (“PV I”) according to ASTM E1052 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension.
15. A composition according to claim 14 , which exhibits a reduction of at least 4.5 log 10 against poliovirus type 1 (Sabin) (“PV1”) according to ASTM E1052 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension.
16. A composition according to claim 1 , wherein the zinc source material is present in an amount of about 0.001% wt. to about 1% wt.
17. A composition according to claim 4 , wherein the zinc source material is present in an amount of about 0.001% wt. to about 1% wt.
18. A composition according to claim 7 , wherein the zinc source material is present in an amount of about 0.001% wt. to about 1% wt.
19. A composition according to claim 8 , wherein the zinc source material is present in an amount of about 0.001% wt. to about 1% wt.