IP Library › Granted Patent US 9,801,914
Granted Patent B2
US 9,801,914 · App. 15/385,554 · Granted Oct 31, 2017

Patent

Inventors: Joseph A. Murray (Rochester, MN); Eric V. Marietta (Rochester, MN); Susan H. Barton (Reston, VA); Veena Taneja (Rochester, MN); Ashutosh Mangalam (Rochester, MN)
Assignee: Mayo Foundation for Medical Education and Research
A61K35/74A61K9/0053A23L33/135A61K9/00A61K35/741C12R1/01
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Quick Facts
Patent No.
US 9,801,914
App. No.
15/385,554
Granted
Oct 31, 2017
Kind
B2
Abstract

This document provides methods and materials related to Prevotella histicola preparations. For example, Prevotella histicola preparations in the form of an oral medicament or dietary supplement (e.g., a pill, tablet, capsule) are provided. In addition, methods and materials for using a Prevotella histicola preparation provided herein as an anti-inflammatory agent are provided.

Claims (7)

1. A method of stimulating an anti-inflammatory response in a mammal, wherein said method comprises orally administering a composition comprising an anti-inflammatory amount of isolated live Prevotella histicola to said mammal, wherein said anti-inflammatory response is stimulated within said mammal.

2. The method of claim 1 , wherein said mammal is a human.

3. The method of claim 1 , wherein said anti-inflammatory response comprises increased expression of IL-10 compared to sham treated control mammals.

4. The method of claim 1 , wherein said anti-inflammatory response comprises reduced expression of IL-17 compared to sham treated control mammals.

5. The method of claim 1 , wherein said composition is a pill, tablet, or capsule.

6. The method of claim 1 , wherein said composition is a pill, tablet, or capsule configured to deliver said Prevotella histicola to the intestines of said mammal.

7. The method of claim 1 , wherein said Prevotella histicola are deposited as NRRL accession number B-50329.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 7, 2017
From: MURRAY, JOSEPH A.; MARIETTA, ERIC V.; BARTON, SUSAN H.; TANEJA, VEENA; MANGALAM, ASHUTOSH
To: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Reel/Frame 042636/0945 →
CONFIRMATORY LICENSE Recorded Jan 13, 2017
From: MAYO CLINIC ROCHESTER
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 040993/0377 →
Continuity (6)
Continuation 14643156 · Mar 10, 2015
Continuation 14086090 · Nov 21, 2013
Continuation 13505169
Provisional Application 61299068 · Jan 28, 2010
Provisional Application 61256731 · Oct 30, 2009
Related Publication 20170189455A1 · Jul 6, 2017