Granted Patent
B2
US 9,808,527 · App. 12/515,886 · Granted Nov 7, 2017
Methods and compositions for treating HIV infections
Inventors:
Arun K. Ghosh (West Lafayette, IN); Hiroaki Mitsuya (Kumamoto, JP); Yasuhiro Koh (Kumamoto, JP)
Assignee:
Purdue Research Foundation
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Abstract
Described herein are compounds and compositions that are useful in the treatment of HIV, AIDS, and AIDS-related diseases. In addition, compounds are described herein that are capable of inhibiting the dimerization of HIV proteases.
Claims (3)
1. A method for treating a patient with HIV, AIDS, or an AIDS-related disease, the method comprising administering to the patient a therapeutically effective amount of at least one compound having protease dimerization inhibitory activity and protease inhibitory activity, wherein the compound is:
and pharmaceutically acceptable salts thereof.
2. The method of claim 1 , wherein the compound having protease dimerization inhibitory activity and protease inhibitory activity is the sole therapeutic agent.
Assignments (3)
CONFIRMATORY LICENSE
Recorded Jun 10, 2016
From: PURDUE UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 038953/0297 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNOR NAME PREVIOUSLY RECORDED AT REEL: 033486 FRAME: 0737. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT.
Recorded Dec 4, 2014
From: KUMAMOTO UNIVERSITY SCHOOL OF MEDICINE
To: PURDUE RESEARCH FOUNDATION
Reel/Frame 034533/0618 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 7, 2014
From: MITSUYA, HIROAKI; KOH, YASUHIRO
To: PURDUE RESEARCH FOUNDATION
Reel/Frame 033486/0737 →
Continuity (3)
Provisional Application
60866786
· Nov 21, 2006
Provisional Application
60945708
· Jun 22, 2007