IP Library › Granted Patent US 9,827,337
Granted Patent B2
US 9,827,337 · App. 14/127,758 · Granted Nov 28, 2017

Cathepsin-binding compounds bound to a carrier and their diagnostic use

Inventors: Olga Vasiljeva (Domzale, SI); Georgy Mikhaylov (Almaty, KZ); Boris Turk (Skofljica, SI); Norbert Schaschke (Bielefeld, DE)
Assignee: J. Stefan Institute
A61K51/08A61K9/127A61K31/00A61K38/08A61K47/48815A61K49/0002A61K49/005A61K49/0052A61K49/0063A61K49/085A61K49/1812
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Quick Facts
Patent No.
US 9,827,337
App. No.
14/127,758
Granted
Nov 28, 2017
Kind
B2
Abstract

The invention relates to Cathepsin-binding compounds bound to a carrier comprising a diagnostic moiety, for use in the diagnosis of inflammatory diseases, and/or for use in the diagnosis of neoplastic diseases, wherein the Cathepsin-binding compound binds to inflammatory cells of the tumour stroma. The invention also relates to Cathepsin B-targeting compounds and Cathepsin B-binding and liposome-binding compounds.

Claims (4)

1. A Cathepsin binding and liposome-binding compound having the structure of formula (XIII):

wherein n=38 to 53.

2. A Cathepsin targeting compound, comprising the Cathepsin binding and liposome-binding compound of claim 1 , bound to a liposome.

3. The Cathepsin targeting compound according to claim 2 , comprising a diagnostic moiety.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 25, 2014
From: VASILJEVA, OLGA; MIKHAYLOV, GEORGY; TURK, BORIS; SCHASCHKE, NORBERT
To: J. STEFAN INSTITUTE
Reel/Frame 032517/0179 →
Priority Claims (1)
EP 11005110 · Jun 22, 2011 · regional
Continuity (1)
Related Publication 20140227175A1 · Aug 14, 2014