Devices and methods using a pathological frequency in electrical stimulation for pain management

1. A non-transitory computer-readable medium having processor-executable instructions for delivering an electrical stimulation signal, the processor-executable instructions when installed onto a device enable the device to perform actions, comprising:

generating an electrical stimulation signal at a pathological frequency in a range of 4 to 8 Hz, wherein the electrical stimulation signal comprises a series of bursts at the pathological frequency, wherein each burst comprises a plurality of pulses within the burst and at a frequency in a range from 1 kHz to 5 kHz; and

delivering the electrical stimulation signal to one or more selected electrodes of an attached lead.

2. The non-transitory computer-readable medium of claim 1 , wherein the actions further comprise sensing a biosignal.

3. The non-transitory computer-readable medium of claim 2 , wherein the actions further comprise repeating the generating, delivering, and sensing actions based on an analysis of the biosignal.

4. A non-transitory computer-readable medium having processor-executable instructions for delivering an electrical stimulation signal, the processor-executable instructions when installed onto a device enable the device to perform actions, comprising:

generating electrical stimulation pulses or pulse bursts with a non-uniform temporal separation between pulses or pulse bursts individually selected based on a pre-determined distribution function based on a pre-selected pathological frequency, wherein the pre-determined distribution function indicates a relative likelihood that a given one of the pulses or pulse bursts will begin at a given time; and

delivering the electrical stimulation pulses or pulse bursts to one or more selected electrodes of an attached lead.

5. The non-transitory computer-readable medium of claim 4 , wherein the pre-determined distribution function is a periodic repeating distribution function.

6. The non-transitory computer-readable medium of claim 4 , wherein the pre-determined distribution function is a sine distribution.

7. The non-transitory computer-readable medium of claim 4 , wherein the pre-determined distribution function is a normal distribution.

8. The non-transitory computer-readable medium of claim 7 , wherein the pre-determined distribution function is a distribution function that resets with each pulse or burst of pulses.

9. The non-transitory computer-readable medium of claim 7 , wherein the actions further comprise sensing a biosignal.

10. The non-transitory computer-readable medium of claim 9 , wherein the actions further comprise repeating the generating, delivering, and sensing actions based on an analysis of the biosignal.

11. A non-transitory computer-readable medium having processor-executable instructions for delivering an electrical stimulation signal, the processor-executable instructions when installed onto a device enable the device to perform actions, comprising:

generating an electrical stimulation signal, wherein the electrical stimulation signal comprises i) a continuous stimulation signal at a pathological frequency in a range of 4 to 8 Hz and ii) a brief burst of pulses during every period or half period of the continuous stimulation signal, wherein each brief burst of pulses comprises a plurality of pukes at a pulse frequency in a range from 500 Hz to 5 kHz; and

delivering the electrical stimulation signal to one or more selected electrodes of an attached lead.

12. The non-transitory computer-readable medium of claim 11 , wherein the actions further comprise sensing a biosignal.

13. The non-transitory computer-readable medium of claim 12 , wherein the actions further comprise repeating the generating, delivering, and sensing actions based on an analysis of the biosignal.