Allomone repulsive and kairomone attractive compositions for controlling arachnids
View Patent ↗Composition of allomones and kairomones derived from the uropygeal gland of ducks and chickens are described, as well as methods to treat Arachnids.
1. An arachnids repulsive composition comprising about 45.0% to 55.0% (w %/w %) bis(2-ethylhexyl) adipate and/or derivatives thereof and/or spatial isomers thereof, and about 45.0% to 55.0% (w %/w %) 2,2,4-trimethyl 1,3 pentanediol diisobutyrate and/or derivatives thereof and/or spatial isomers thereof.
2. An arachnids repulsive composition consisting of bis(2-ethylhexyl) adipate and/or derivatives thereof and/or spatial isomers thereof, and 2,2,4-trimethyl 1,3 pentanediol diisobutyrate and/or derivatives thereof and/or spatial isomers thereof.
3. The arachnids repulsive composition according to claim 2 , which consists of about 45.0% to 55.0% (w %/w %) bis(2-ethylhexyl) adipate and/or derivatives thereof and/or spatial isomers thereof, and about 45.0% to 55.0% (w %/w %) 2,2,4-trimethyl-1,3 pentanediol diisobutyrate and/or derivatives thereof and/or spatial isomers thereof.
4. The composition according to claim 2 , wherein said derivatives are esters, or salts, alcohols, ketones, ethers, aldehydes, sterols and amides of bis(2-ethylhexyl) adipate and 2,2,4-trimethyl 1,3 pentanediol diisobutyrate.
5. A method of repulsing arachnids said method comprising administering to an animal in need of such treatment a pharmaceutically acceptable amount of a composition according to claim 1 or 2 .
6. A method of treating or preventing chicken mites or Northern fowl mites in hens, chickens and young chicks said method comprising administering to hens, chickens or young chicks in need of such treatment a pharmaceutically effective amount of a composition according to claim 1 or 2 .
7. The method according to claim 5 , wherein said composition comprises about 45.0% to 55.0% (w %/w %) bis(2-ethylhexyl) adipate and about 45.0% to 55.0% (w %/w %) 2,2,4-trimethyl-1,3 pentanediol diisobutyrate and/or derivatives thereof and/or isomers thereof and/or mixtures of bis(2-ethylhexyl) adipate or 2,2,4-trimethyl 1,3 pentanediol diisobutyrate with one or more esters, or salts, alcohols, ketones, ethers, aldehydes, sterols and amides derivatives of bis(2-ethylhexyl) adipate and 2,2,4-trimethyl 1,3 pentanediol diisobutyrate and/or with one or more isomers of bis(2-ethylhexyl) adipate and 2,2,4-trimethyl 1,3 pentanediol diisobutyrate and/or one or more isomers of the derivatives of bis(2-ethylhexyl) adipate and 2,2,4-trimethyl 1,3 pentanediol diisobutyrate.
8. The method according to claim 6 , wherein said composition comprises about 45.0% to 55.0% (w %/w %) bis(2-ethylhexyl) adipate and about 45.0% to 55.0% (w %/w %) 2,2,4-trimethyl-1,3 pentanediol diisobutyrate and/or derivatives thereof and/or isomers thereof and/or mixtures of bis(2-ethylhexyl) adipate or 2,2,4-trimethyl 1,3 pentanediol diisobutyrate with one or more esters, or salts, alcohols, ketones, ethers, aldehydes, sterols and amides derivatives of bis(2-ethylhexyl) adipate and 2,2,4-trimethyl 1,3 pentanediol diisobutyrate and/or with one or more isomers of bis(2-ethylhexyl) adipate and 2,2,4-trimethyl 1,3 pentanediol diisobutyrate and/or one or more isomers of the derivatives of bis(2-ethylhexyl) adipate and 2,2,4-trimethyl 1,3 pentanediol diisobutyrate.
9. The method according to claim 5 , wherein said administering comprises oral administration.
10. The method according to claim 6 , wherein said administering comprises oral administration.
11. The method according to claim 7 , wherein said administering comprises oral administration.
12. The method according to claim 5 , wherein said administering comprises a topical administration.
13. The method according to claim 6 , wherein said administering comprises a topical administration.
14. The method according to claim 7 , wherein said administering comprises a topical administration.
15. A solution comprising the arachnids repulsive composition of claim 1 .
16. A method of repulsing arachnids said method comprising administering to a human in need of such treatment a pharmaceutically acceptable amount of a composition according to claim 1 or 2 .
17. The method according to claim 5 , wherein said arachnid is a Dermanyssus gallinae , a tick or an Ornithonyssus sylviarum.
18. The method according to claim 16 , wherein said arachnid is a Dermanyssus gallinae , a tick or an Ornithonyssus sylviarum.
19. The composition according to claim 1 , wherein said derivatives are esters, or salts, alcohols, ketones, ethers, aldehydes, sterols and amides of bis(2-ethylhexyll) adipate and 2,2,4-trimethyl 1,3 pentanediol diisobutyrate.
20. A solution comprising the arachnids repulsive composition of claim 2 .
21. The solution according to claim 15 , wherein said solution comprises a nonaqueous solvent selected from the group consisting of alcohol, diethyl ether, chloroform, ethanol, benzene, propyl alcohol, isopropanol, 2-propanol and acetone polysorbate 80.
22. The solution according to claim 20 , wherein said solution comprises a nonaqueous solvent selected from the group consisting of alcohol, diethyl ether, chloroform, ethanol, benzene, propyl alcohol, isopropanol, 2-propanol and acetone polysorbate 80.
23. The solution according to claim 15 , wherein said solution comprises a solvent of water, or vegetal or animal oil.
24. The solution according to claim 20 , wherein said solution comprises a solvent of water, or vegetal or animal oil.
25. The composition according to claim 1 , comprising about 45.0% to 55.0% (w %/w %) bis(2-ethylhexyl) adipate and/or derivatives thereof, and about 45.0% to 55.0% (w %/w %) 2,2,4-trimethyl 1,3 pentanediol diisobutyrate and/or derivatives thereof, wherein said derivatives are esters, or salts, alcohols, ketones, ethers, aldehydes, sterols and amides of bis(2-ethylhexyl) adipate and 2,2,4-trimethyl 1,3 pentanediol diisobutyrate.
26. The composition according to claim 1 , comprising about 45.0% to 55.0% (w %/w %) bis(2-ethylhexyl) adipate and about 45.0% to 55.0% (w %/w %) 2,2,4-trimethyl 1,3 pentanediol diisobutyrate.
27. The composition according to claim 2 , wherein said derivatives are esters, or salts, alcohols, ketones, ethers, aldehydes, sterols and amides of bis(2-ethylhexyl) adipate and 2,2,4-trimethyl 1,3 pentanediol diisobutyrate.
28. The composition according to claim 2 , or consisting of bis(2-ethylhexyl) adipate and 2,2,4-trimethyl 1,3 pentanediol diisobutyrate.
29. The composition according to claim 27 , which consists of about 45.0% to 55.0% (w %/w %) bis(2-ethylhexyl) adipate and/or derivatives thereof, and about 45.0% to 55.0% (w %/w %) 2,2,4-trimethyl-1,3 pentanediol diisobutyrate and/or derivatives thereof.
30. The composition according to claim 28 , which consists of about 45.0% to 55.0% (w %/w %) bis(2-ethylhexyl) adipate and about 45.0% to 55.0% (w %/w %) 2,2,4-trimethyl-1,3 pentanediol diisobutyrate.