IP Library Granted Patent US 9,907,520
Granted Patent B2
US 9,907,520 · App. 15/205,787 · Granted Mar 6, 2018

Digital tomosynthesis systems, methods, and computer readable media for intraoral dental tomosynthesis imaging

Inventors: Otto Z. Zhou (Chapel Hill, NC); Jianping Lu (Chapel Hill, NC); Jing Shan (Chapel Hill, NC); Andrew Tucker (Cary, NC); Pavel Chtcheprov (Chapel Hill, NC); Enrique Platin (Cary, NC); André Mol (Chapel Hill, NC); Laurence Rossman Gaalaas (Carrboro, NC); Gongting Wu (Chapel Hill, NC)
Assignees: The University of North Carolina at Chapel Hill; XINTEK, INC.
A61B6/145A61B6/025A61B6/06A61B6/4007A61B6/4035A61B6/425A61B6/4405A61B6/461A61B6/5205A61B6/5217A61B6/547A61B6/582A61B6/587
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Quick Facts
Patent No.
US 9,907,520
App. No.
15/205,787
Granted
Mar 6, 2018
Kind
B2
Abstract

Digital tomosynthesis systems, methods, and computer readable media for intraoral dental tomosynthesis imaging are disclosed. In some aspects, an intraoral tomosynthesis imaging system includes an x-ray source array for positioning outside a mouth of a patient, wherein the x-ray source array contains multiple x-ray focal spots that are spatially distributed on an anode, an area digital x-ray detector for positioning inside the mouth of the patient, a geometry calibration mechanism for connecting the x-ray detector to the x-ray source array, an x-ray collimator for confining x-ray beams to a region of interest, a controller for regulating x-ray radiation and synchronization of the x-ray radiation with the x-ray detector, such that multiple 2D projection images of the ROI are acquired without mechanical motion of the x-ray source array, the x-ray detector, or the mouth of the patient, and a computer program and workstation for 3D tomosynthesis image reconstruction and display.

Claims (23)

1. An intraoral tomosynthesis imaging system comprising:

an x-ray source array for positioning outside a mouth of a patient, wherein the x-ray source array contains multiple x-ray focal spots that are spatially distributed on one or multiple anode(s);

an area digital x-ray detector for positioning inside the mouth of the patient;

an x-ray collimator for confining x-ray beams to a region of interest (ROI);

a controller for regulating x-ray radiation and synchronizing the x-ray exposure with the x-ray detector, such that multiple two-dimensional (2D) projection images of the ROI are acquired without moving the x-ray source array, the area digital x-ray detector, or the mouth of the patient; and

a computer processor for three-dimensional (3D) tomosynthesis image reconstruction and display.

2. The system of claim 1 , further comprising a geometry calibration mechanism to determine the relative position of the x-ray detector placed inside the mouth of the patient with respect to the x-ray source array.

3. The system of claim 2 , wherein the geometry calibration mechanism comprises a magnetic attachment attachable to the area digital x-ray detector while inside the mouth of the patient in order to connect the x-ray source array to the area digital x-ray detector.

4. The system of claim 1 , wherein the x-ray source array is a field emission x-ray source array.

5. An intraoral three-dimensional (3D) imaging system comprising:

an x-ray source array for positioning outside a mouth of a patient, wherein the x-ray source array contains 3 to 100 x-ray focal spots that are spatially distributed on an anode and spanning an angular range approximately between 3 and 25 degrees, each of the x-ray focal spots being approximately between 0.05 and 2 mm in size;

an area digital x-ray detector for positioning inside the mouth of the patient;

a geometry calibration mechanism connectable to the area digital x-ray detector;

an x-ray collimator for confining x-ray beams to a region of interest (ROI);

an electronic controller for regulating x-ray radiation and synchronization of the x-ray radiation with the area digital x-ray detector, such that multiple two-dimensional (2D) projection images of the ROI are acquired without mechanical motion of the x-ray source array, the area digital x-ray detector, or the mouth of the patient; and

a computer processor with executable programs for geometry calibration, tomosynthesis reconstruction, and image display.

6. A method for dual energy intraoral three-dimensional (3D) tomographic imaging, the method comprising:

positioning an area digital x-ray detector at a first position inside the mouth of the patient;

positioning an x-ray source array outside a mouth of a patient, wherein the x-ray source array comprises multiple x-ray focal spots that are spatially distributed on an anode;

acquiring two sets of two-dimensional (2D) projection images of a same region of interest at two different x-ray energies; and

processing the two sets of 2D projection images to obtain a reconstructed 3D tomography image with high contrast.

7. The geometry calibration mechanism of claim 2 , further configured to provide motion tracking capability during the imaging procedure to dynamically determine the relative position of the x-ray detection with respect to the x-ray source when there is unintentional movement.

8. The geometry calibration device of claim 2 , further comprising one or multiple light source(s) mounted on either the x-ray source or the collimator; a screen; a camera; and a mechanism to determine position of the detector with respect to the x-ray source using optical images formed on the screen and captured by the camera.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 6, 2018
From: XINTEK, INC.
To: XINVIVO, INC.
Reel/Frame 045512/0105 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 30, 2016
From: ZHOU, OTTO Z.; LU, JIANPING; SHAN, JING; CHTCHEPROV, PAVEL; PLATIN, ENRIQUE; MOL, ANDRÉ; GAALAAS, LAURENCE R.; WU, GONGTING; TUCKER, ANDREW
To: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL; XINTEK, INC.
Reel/Frame 039586/0866 →
Continuity (4)
Continuation 14741041 · Jun 16, 2015
Provisional Application 62143443 · Apr 6, 2015
Provisional Application 62013181 · Jun 17, 2014
Related Publication 20160317107A1 · Nov 3, 2016