Use of flaxseed and flaxseed derivatives for treatment of neurological disorders and viral diseases
View Patent ↗The invention provides compositions and methods for treating neurological disorders and viral infection using whole-grain flaxseed, flaxseed lignans such as Secoisolariciresinol diglucoside (SDG), human lignans metabolized from flaxseed such as Enterodiol (ED) or Enterolactone (EL), and synthetic flaxseed lignan analogs.
1. A method for treating infection-mediated neuronal damage in a subject having infection-mediated neuronal damage comprising the step of administering to said subject a therapeutically effective amount of a lignan, wherein said lignan is a flaxseed lignan selected from the group consisting of a flaxseed lignan complex (FLC) and secoisolariciresinol diglucoside (SDG).
2. The method of claim 1 , wherein said lignan is administered in the form of a flaxseed lignan complex (FLC).
3. The method of claim 1 , wherein said lignan is a flaxseed lignan and said flaxseed lignan is secoisolariciresinol diglucoside (SDG).
4. The method of claim 1 , wherein said step of administering comprises oral administration.
5. The method of claim 1 , wherein said infection is a viral infection or a bacterial infection.
6. The method of claim 5 , wherein said subject is a human and said infection is human immunodeficiency virus (HIV) infection.
7. The method of claim 6 , wherein said subject is receiving antiretroviral therapy.
8. The method of claim 6 , wherein said subject is diagnosed with HIV-associated Neurocognitive Disorder (HAND).