Patterned neo-epithelialization dressings, systems, and methods
Systems, methods, and apparatuses are presented that involve forming patterns on neo-epithelium that allow increased functionality and may more nearly resemble the original epithelium. In one instance, a patterned neo-epithelium dressing for treating a tissue site having granulation tissue includes an interface member for placing proximate the granulation tissue and a plurality of three-dimensional features formed on a second, patient-facing side of the interface member. Other systems, methods, and apparatuses are disclosed.
1. A patterned neo-epithelium dressing for treating a skin tissue site having granulation tissue, the patterned neo-epithelium dressing comprising:
an interface member having a first side; and
a second, patient-facing side configured to be placed proximate to the granulation tissue,
the second, patient-facing side of the interface member having a surface topography defined by a plurality of ridges and grooves formed in a pattern to mimic intact human skin.
2. The patterned neo-epithelium dressing of claim 1 , wherein the interface member is formed with a fluid passageway that fluidly couples the first side and the second, patient-facing side.
3. The patterned neo-epithelium dressing of claim 1 , wherein the interface member has a plurality of pores having an average pore size greater than 5 μm and smaller than 1000 μm.
4. The patterned neo-epithelium dressing of claim 1 , wherein the pattern is configured to mimic an intact analogous human skin pattern based on the patient's skin near the wound or a duplicate body part.
5. The patterned neo-epithelium dressing of claim 1 , wherein the pattern is configured to mimic a location-specific human skin pattern based on the general features of a specific area of a generic body.
6. The patterned neo-epithelium dressing of claim 1 , wherein the interface member comprises a thin member bonded to a foam.
7. The patterned neo-epithelium dressing of claim 1 , wherein the interface member comprises:
a thin member having a first side and a second, patient-facing side;
a hydrophilic material having a first side and a second, patient-facing side; and
wherein the second, patient-facing side of the hydrophilic material is coupled to the first side of the thin member.
8. The patterned neo-epithelium dressing of claim 1 , further comprising a protein coated on the plurality of ridges and grooves.
9. A method of treating a wound at a tissue site of a patient, the method comprising:
locating granulation tissue at the tissue site;
deploying a patterned neo-epithelium dressing on the granulation tissue, the dressing comprising: an interface member having (i) a first side, (ii) a second, patient-facing side, and (iii) the second patient-facing side having a surface topography defined by a plurality of ridges and grooves formed in a pattern configured to mimic intact human skin, and wherein the second, patient-facing side is deployed proximate the granulation tissue; and
applying a contact pressure on the patterned neo-epithelium dressing.
10. The method of claim 9 , wherein the locating comprises promoting the formation of granulation tissue using reduced pressure at the tissue site.
11. The method of claim 10 , wherein the step of promoting the formation of granulation tissue comprises applying a reduced-pressure manifold proximate to the tissue site, covering the reduced-pressure manifold with a sealing member, and providing reduced pressure to the reduced-pressure manifold.
12. The method of claim 9 , wherein applying the contact pressure comprises:
deploying a sealing member over the patterned neo-epithelium dressing and a portion of the patient's skin, the sealing member having a first side and a second, patient-facing side; and
providing reduced pressure to the second, patient-facing side of the sealing member.
13. The method of claim 9 , wherein applying the contact pressure comprises deploying a pressure wrap over the first side of the patterned neo-epithelium dressing.
14. The method of claim 9 , wherein the interface member has a plurality of pores having an average pore size greater than 5 μm and smaller than 1000 μm.
15. A system for treating a skin tissue site having granulation tissue on a patient, the system comprising:
a patterned neo-epithelium dressing configured to be disposed proximate to granulation tissue on the skin tissue site, wherein the patterned neo-epithelium dressing comprises: an interface member having (i) a first side, (ii) a second, patient-facing side configured to be placed proximate the granulation tissue, the second, patient-facing side having a surface topography defined by a plurality of ridges and grooves formed in a pattern configured to mimic intact human skin, and (ii) one or more fluid passageways that fluidly couple the first side and the second, patient-facing side;
a sealing member for placing over the patterned neo-epithelium dressing and the patient's epidermis;
a reduced-pressure interface fluidly coupled to the sealing member; and
a reduced-pressure source fluidly coupled to the reduced-pressure interface.
16. The system of claim 15 , the interface member has a plurality of pores having an average pore size larger than 5 μm and smaller than 1000 μm.
17. The system of claim 15 , wherein the pattern is configured to mimic intact analogous human skin pattern based on the patient's skin near the wound or a duplicate body part.
18. The system of claim 15 , wherein the pattern is configured to mimic a location-specific human skin pattern based on a specific area of a generic human body.
19. The system of claim 15 , wherein the interface member comprises a polyurethane film bonded to a foam.