Patent Assignment
Reel/Frame 074858/0456
Release of Security Interest
Recorded: 2026-02-13
Pages: 25
Assignor
TRINITY CAPITAL INC.
Executed: 2026-02-10
Assignee
TAYSHA GENE THERAPIES, INC.
3000 PEGASUS PARK DRIVE, SUITE 1430, DALLAS, TEXAS, 75247
Covered Properties
(71)
Transgene Cassettes Designed to Express a Human Codon-Optimized Gene MECP2
Application:
62/944,209 →
Transgene Cassettes Designed to Express a Human MECP2
Application:
62/946,696 →
Transgene Cassettes Designed to Express a Human MECP2 Gene
Application:
63/008,159 →
Transgene Cassettes Designed to Express a Human MECP2 Gene
Application:
63/047,596 →
Transgene Cassettes Designed to Express a Human MECP2 Gene
Transgene Cassettes Designed to Express a Human MECP2 Gene
Transgene Cassettes Designed to Express a Human MECP2 Gene
Application:
19/233,521 →
Publication:
US 2025/0297285
Gene Therapy for Angelman Syndrome
Application:
63/145,123 →
Gene Therapy for Angelman Syndrome
Application:
63/221,682 →
Gene Therapy for Angelman Syndrome
Application:
18/274,485 →
Publication:
US 2024/0318198
MECP2 Based Therapy
Application:
16/497,271 →
Publication:
US 2021/0101938
MECP2 Based Therapy
Application:
19/051,709 →
Publication:
US 2025/0387519
MECP2 Expression Cassettes
MECP2 Expression Cassettes
Application:
18/503,439 →
Publication:
US 2024/0165270
Optimized CLN1 Genes and Expression Cassettes and Their Use
Application:
62/349,411 →
Optimized CLN1 Genes and Expression Cassettes and Their Use
Optimized CLN1 Genes and Expression Cassettes and Their Use
Optimized CLN1 Genes and Expression Cassettes and Their Use
Application:
19/080,388 →
Feedback Enabled Synthetic Genes, Target Seed Match Cassettes, and Their Uses
Application:
62/725,126 →
Feedback Enabled Synthetic Genes, Target Seed Match Cassettes, and Their Uses
Application:
62/861,044 →
Feedback Enabled Synthetic Genes, Target Seed Match Cassettes, and Their Uses
Feedback Enabled Synthetic Genes, Target Seed Match Cassettes, and Their Uses
Application:
19/194,475 →
Publication:
US 2025/0269061
Tau Reduction Gene Therapy
Application:
63/215,833 →
Methods and Compositions for Tau Reduction Gene Therapy
Application:
63/267,440 →
Methods and Compositions for Tau Reduction Gene Therapy
Application:
63/342,240 →
Methods and Compositions for Tau Reduction Gene Therapy
Application:
18/569,019 →
Publication:
US 2024/0269161
Intrathecal and Intravenous Combination Gene Therapy for the Treatment of Infantile Batten Disease
Application:
62/840,360 →
Intrathecal and Intravenous Combination Gene Therapy for the Treatment of Infantile Batten Disease
Application:
17/607,315 →
Publication:
US 2022/0193268
Aav-Rnai Transgene Cassettes Designed to Downregulate Human GYS1 as a Therapy for Glycogen Storage Disorders
Application:
63/281,336 →
Rnai Therapy for Apbd and Lafora Disease
Application:
18/709,305 →
Publication:
US 2025/0011791
Transgene Casette Designed to Express the Human Codon-Optimized Gene FMR1
Application:
63/267,236 →
Transgene Cassettes Designed to Express the Human Codon-Optimized Gene FMR1
Application:
18/729,389 →
Publication:
US 2025/0082782
Transgene Cassettes Designed to Express Ae Human Codon-Optimized Gene SLC6A1
Application:
62/932,824 →
Transgene Cassettes, Aav Vectors and Aav Viral Vectors for the Expression of Human Codon-Optimized SLC6A1
Transgene Cassettes Designed to Express the Human Codon-Optimized Gene SURF1
Application:
62/932,828 →
Recombinant Adeno-Associated Viral Vector for Gene Delivery
Compositions and Methods for Treatment of Neurological Disorders
Application:
63/010,179 →
Compositions and Methods for Treatment of Neurological Disorders
Compositions and Methods for Treatment of Neurological Disorders
SLC13A5 Gene Therapy Vectors and Uses Thereof
Application:
63/250,761 →
SLC13A5 Gene Therapy Vectors and Uses Thereof
Application:
63/364,655 →
UBE3A Genes and Expression Cassettes and Their Use
Application:
62/851,411 →
UBE3A Genes and Expression Cassettes and Their Use
Gene Therapy for Prader Willi Syndrome
Application:
63/274,723 →
Optimized SLC13A5 Genes and Expression Cassettes and Their Use
Application:
18/006,278 →
Publication:
US 2023/0285595
Methods and Gene Therapy Constructs for Treating GM2 Gangliosidoses
Application:
62/348,003 →
Methods and Gene Therapy Constructs for Treating GM2 Gangliosidoses
Methods and Gene Therapy Constructs for Treating GM2 Gangliosidoses
Optimized SUMF1 Genes and Expression Cassettes and Their Use
Application:
62/840,114 →
Optimized SUMF1 Genes and Expression Cassettes and Their Use
GNAO1 Gene Therapy Vectors and Uses Thereof
Application:
63/285,682 →
Vector Genome Design to Express Optimized CLN7 Transgene
Application:
63/284,852 →
Pten Gene Therapy Vectors and Uses Thereof
Application:
63/441,925 →
Transgene Cassettes Designed to Express a Human MECP2 Gene
PCT:
PCT/US2020/063300 ↗
Gene Therapy for Angelman Syndrome
PCT:
PCT/US2022/014926 ↗
Optimized CLN1 Genes and Expression Cassettes and Their Use
PCT:
PCT/US2017/037118 ↗
Feedback Enabled Synthetic Genes, Target Seed Match Cassettes, and Their Uses
PCT:
PCT/US2019/048776 ↗
Methods and Compositions for Tau Reduction Gene Therapy
PCT:
PCT/US2022/035091 ↗
Intrathecal and Intravenous Combination Gene Therapy for the Treatment of Infantile Batten Disease
PCT:
PCT/US2020/030427 ↗
Rnai Therapy for Apbd and Lafora Disease
PCT:
PCT/US2022/080028 ↗
Transgene Casette Designed to Express the Human Codon-Optimized Gene FMR1
PCT:
PCT/US2023/061459 ↗
Transgene Cassettes, Aav Vectors and Aav Viral Vectors for the Expression of Human Codon-Optimized SLC6A1
PCT:
PCT/US2020/059576 ↗
Recombinant Adeno-Associated Viral Vector for Gene Delivery
PCT:
PCT/US2020/059570 ↗
Compositions and Methods for Treatment of Neurological Disorders
PCT:
PCT/US2021/027266 ↗
SLC13A5 Gene Therapy Vectors and Uses Thereof
PCT:
PCT/US2022/077274 ↗
UBE3A Genes and Expression Cassettes and Their Use
PCT:
PCT/US2020/034171 ↗
Gene Therapy for Prader Willi Syndrome
PCT:
PCT/US2022/079117 ↗
Optimized SLC13A5 Genes and Expression Cassettes and Their Use
PCT:
PCT/US2021/042930 ↗
Optimized SUMF1 Genes and Expression Cassettes and Their Use
PCT:
PCT/US2020/030236 ↗
GNAO1 Gene Therapy Vectors and Uses Thereof
PCT:
PCT/US2022/080805 ↗
Vector Genome Design to Express Optimized CLN7 Transgene
PCT:
PCT/US2022/080625 ↗
Related Assignments
(25)
Other recorded transfers of the patents in this record — the chain of ownership.
Assignment of Assignor's Interest
Jun 20, 2016
From: GRAY, STEVEN
To: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Reel/Frame 038955/0276 →
Assignment of Assignor's Interest
Sep 20, 2018
From: GRAY, STEVEN JAMES; SINNETT, SARAH
To: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Reel/Frame 046922/0309 →
Assignment of Assignor's Interest
Jan 8, 2019
From: GRAY, STEVEN
To: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Reel/Frame 047930/0139 →
Assignment of Assignor's Interest
Jun 20, 2019
From: GRAY, STEVEN JAMES; SINNETT, SARAH
To: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Reel/Frame 049542/0448 →
Assignment of Assignor's Interest
Apr 20, 2020
From: GRAY, STEVEN
To: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Reel/Frame 052447/0707 →
Assignment of Assignor's Interest
Nov 24, 2020
From: GRAY, STEVEN J; SINNETT, SARAH
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 054459/0065 →
Assignment of Assignor's Interest
Dec 1, 2020
From: GRAY, STEVEN J; SINNETT, SARAH
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 054507/0400 →
Assignment of Assignor's Interest
Dec 18, 2020
From: GRAY, STEVEN J; SINNETT, SARAH
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 054694/0371 →
Assignment of Assignor's Interest
Dec 18, 2020
From: GRAY, STEVEN J; SINNETT, SARAH
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 054694/0427 →
Assignment of Assignor's Interest
Dec 18, 2020
From: GRAY, STEVEN J; SINNETT, SARAH
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 054694/0396 →
Assignment of Assignor's Interest
Feb 4, 2021
From: BUTLER, RYAN; GRAY, STEVEN J.
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 055140/0241 →
Assignment of Assignor's Interest
Mar 16, 2021
From: GRAY, STEVEN JAMES; SINNETT, SARAH
To: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Reel/Frame 055604/0487 →
Assignment of Assignor's Interest
Jun 29, 2021
From: BAILEY, RACHEL M.
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 056706/0256 →
Assignment of Assignor's Interest
Nov 1, 2021
From: BUTLER, RYAN; GRAY, STEVEN J; KANG, HYE RI
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 057980/0807 →
Assignment of Assignor's Interest
Nov 1, 2021
From: BUTLER, RYAN; GRAY, STEVEN J; KANG, HYE
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 057980/0815 →
Assignment of Assignor's Interest
Dec 10, 2021
From: MILLER, TIMOTHY J.
To: ABEONA THERAPEUTICS, INC.
Reel/Frame 058358/0921 →
Assignment of Assignor's Interest
Dec 10, 2021
From: GRAY, STEVEN J.
To: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Reel/Frame 058358/0891 →
Assignment of Assignor's Interest
Feb 11, 2022
From: BAILEY, RACHEL
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 058989/0165 →
Assignment of Assignor's Interest
May 2, 2022
From: MINASSIAN, BERGE; GUMUSGOZ, EMRAH; VERMA, MAYANK
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 059782/0298 →
Assignment of Assignor's Interest
May 9, 2022
From: BIRD, ADRIAN; TILLOTSON, REBEKAH; COBB, STUART ROBERT; HECTOR, RALPH DAVID
To: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW
Reel/Frame 059867/0767 →
Assignment of Assignor's Interest
Jun 3, 2022
From: BAILEY, RACHEL
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 060096/0450 →
Assignment of Assignor's Interest
Apr 13, 2023
From: TILLOTSON, REBEKAH
To: THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH
Reel/Frame 063319/0035 →
Assignment of Assignor's Interest
Apr 13, 2023
From: BIRD, ADRIAN
To: THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH
Reel/Frame 063318/0714 →
Assignment of Assignor's Interest
Apr 13, 2023
From: COBB, STUART ROBERT
To: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW
Reel/Frame 063319/0814 →
Assignment of Assignor's Interest
Apr 13, 2023
From: HECTOR, RALPH DAVID
To: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW
Reel/Frame 063319/0991 →