Patent Assignment
Reel/Frame 075391/0617
Assignment of Assignor's Interest
Recorded: 2026-04-10
Pages: 27
Assignor
EXOSOME DIAGNOSTICS, INC.
Executed: 2026-01-09
Assignee
EXACT SCIENCES CORPORATION
5505 ENDEAVOR LANE, MADISON, WISCONSIN, 53719
Covered Properties
(65)
Method for Isolation of Nucleic Acid Containing Particles and Extraction of Nucleic Acids Therefrom
Application:
61/412,369 →
Method for Isolation of Nucleic Acid Containing Particles and Extraction of Nucleic Acids Therefrom
Application:
13/883,673 →
Publication:
US US20130295574A1
Method for Isolation of Nucleic Acid Containing Particles and Extraction of Nucleic Acids Therefrom
Method for Isolation of Nucleic Acid Containing Particles and Extraction of Nucleic Acids Therefrom
Method for Isolation of Nucleic Acid Containing Particles and Extraction of Nucleic Acids Therefrom
Application:
19/181,038 →
Publication:
US US20250290062A1
Nucleic Acid Extraction from Heterogeneous Biological Materials
Application:
61/485,112 →
Nucleic Acid Extraction from Heterogeneous Biological Materials
Application:
14/116,372 →
Publication:
US US20140212871A1
Nucleic Acid Extraction from Heterogeneous Biological Materials
Cerebrospinal Fluid Assay
Application:
61/558,400 →
Cerebrospinal Fluid Assay
Controls for Nucleic Acid Assays
Application:
61/695,116 →
Controls for Nucleic Acid Assays
Controls for Nucleic Acid Assays
Use for Microvesicles in Diagnosis, Prognosis and Treatment of Medical Diseases and Conditions
Application:
61/709,337 →
Use of Microvesicles in Diagnosis, Prognosis, and Treatment of Medical Diseases and Conditions
Application:
14/433,460 →
Publication:
US US20150252428A1
Methods for Isolating Microvesicles
Application:
61/748,575 →
Methods for Isolating Microvesicles
Application:
14/759,238 →
Publication:
US US20150353920A1
Methods for Isolating Microvesicles
Application:
16/893,966 →
Publication:
US US20210171934A1
Methods for Isolating Microvesicles and Extracting Nucleic Acids from Biological Samples
Application:
62/022,538 →
Methods for Isolating Microvesicles and Extracting Nucleic Acids from Biological Samples
Application:
62/079,763 →
Methods for Isolating Microvesicles and Extracting Nucleic Acids from Biological Samples
Application:
62/166,890 →
Methods for Isolating Microvesicles and Extracting Nucleic Acids from Biological Samples
Methods for Isolating Microvesicles and Extracting Nucleic Acids from Biological Samples
Novel EGFR Variant
Application:
61/765,537 →
A Novel EGFR Variant
Application:
14/768,275 →
Publication:
US US20160075788A1
Novel Egfr Variant
Application:
16/261,241 →
Publication:
US US20190211106A1
Fully Automated High-Throughput Method for Isolation of Extracellular Vesicles and Co-Isolation of Cell-Free Dna from Biofluids
Application:
62/336,203 →
Automated and Manual Methods for Isolation of Extracellular Vesicles and Co-Isolation of Cell-Free Dna from Biofluids
Automated and Manual Methods for Isolation of Extracellular Vesicles and Co-Isolation of Cell-Free Dna from Biofluids
Application:
17/074,040 →
Publication:
US US20210238582A1
Methods and Compositions to Detect T790M in Plasma Using Exosomal Rna and Cell Free Dna from Non-Small Cell Lung Cancer Patients
Application:
62/428,059 →
Methods and Compositions to Detect Mutations in Plasma Using Exosomal Rna and Cell Free Dna from Non-Small Cell Lung Cancer Patients
Sequencing of nucleic acids associated with exosomal isolation from patients with glioblastoma multiforme
Application:
62/534,141 →
Methods of Treating Glioblastoma in a Subject Informed by Exosomal Rna Signatures
Methods of Detecting Sjogren?S Syndrome Using Salivary Exosomes
Application:
63/404,242 →
Methods of Detecting SjöGren's Syndrome Using Salivary Exosomes
Application:
19/109,403 →
Publication:
US US20260078448A1
Methods for Isolating and Enriching Populations of Biofluid-Derived Extracellular Vesicles, and Methods of Use Thereof
Application:
62/531,845 →
Methods for Isolating and Enriching Populations of Neuronally-Derived Extracellular Vesicles, and Methods of Use Thereof
Application:
62/678,853 →
Treatment and Diagnosis of Parkinson's Disease Using Isolated and Enriched Populations of Biofluid-Derived Extracellular Vesicles
Complete RNA sequencing of plasma exosomes
Application:
62/410,974 →
Sequencing and analysis of exosome associated nucleic acids
Application:
62/536,545 →
Sequencing and Analysis of Exosome Associated Nucleic Acids
Compositions and Methods for Internal Controls of Microvesicle Isolations
Application:
62/769,745 →
Compositions and Methods for Internal Controls of Microvesicle Isolations
Compositions, Methods, and Kits for the Isolation of Extracellular Vesticles
Application:
62/902,058 →
Compositions, Methods, and Kits for the Isolation of Extracellular Vesicles
Compositions, Methods, and Kits for the Isolation of Extracellular Vesicles
Application:
19/386,689 →
Publication:
US US20260210951A1
Methods of Detecting SjöGren's Syndrome Using Salivary Exosomes
Application:
63/222,823 →
Methods of Detecting Sjogren's Syndrome Using Salivary Exosomes
Application:
18/579,636 →
Publication:
US US20250075258A1
Method for Isolation of Nucleic Acid Containing Particles and Extraction of Nucleic Acids Therefrom
PCT:
PCT/US2011/060251 ↗
Nucleic Acid Extraction from Heterogeneous Biological Materials
PCT:
PCT/US2012/037443 ↗
Cerebrospinal Fluid Assay
PCT:
PCT/US2012/064677 ↗
Controls for Nucleic Acid Assays
PCT:
PCT/US2013/057506 ↗
Use of Microvesicles in Diagnosis, Prognosis, and Treatment of Medical Diseases and Conditions
PCT:
PCT/US2013/063292 ↗
Methods for Isolating Microvesicles
PCT:
PCT/US2014/010173 ↗
Methods for Isolating Microvesicles and Extracting Nucleic Acids from Biological Samples
PCT:
PCT/US2015/039760 ↗
A Novel Egfr Variant
PCT:
PCT/US2014/016536 ↗
Automated and Manual Methods for Isolation of Extracellular Vesicles and Co-Isolation of Cell-Free Dna from Biofluids
PCT:
PCT/US2017/032719 ↗
Methods and Compositions to Detect Mutations in Plasma Using Exosomal Rna and Cell Free Dna from Non-Small Cell Lung Cancer Patients
PCT:
PCT/US2017/062370 ↗
Sequencing of Nucleic Acids Associated with Exosomal Isolation from Patients with Glioblastoma Multiforme
PCT:
PCT/US2018/042708 ↗
Methods of Detecting Sjogren’S Syndrome Using Salivary Exosomes
PCT:
PCT/US2023/032192 ↗
Methods for Isolating and Enriching Populations of Biofluid- Derived Extracellular Vesicles, and Methods of Use Thereof
PCT:
PCT/US2018/041884 ↗
Sequencing and Analysis of Exosome Associated Nucleic Acids
PCT:
PCT/US2017/057916 ↗
Compositions and Methods for Internal Controls of Microvesicle Isolations
PCT:
PCT/US2019/062429 ↗
Compositions, Methods, and Kits for the Isolation of Extracellular Vesicles
PCT:
PCT/US2020/051520 ↗
Methods of Detecting Sjogren's Syndrome Using Salivary Exosomes
PCT:
PCT/US2022/037469 ↗
Related Assignments
(22)
Other recorded transfers of the patents in this record — the chain of ownership.
Assignment of Assignor's Interest
Nov 8, 2011
From: SKOG, JOHAN KARL OLOV; RUSSO, LEILEATA M.
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 027193/0030 →
Assignment of Assignor's Interest
Jan 23, 2012
From: SKOG, JOHAN KARL OLOV, DR.
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 027575/0834 →
Assignment of Assignor's Interest
Jan 23, 2012
From: COMPER, WAYNE, DR.; RUSSO, LEILEATA M., DR.; SKOG, JOHAN KARL OLOV, DR.
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 027573/0815 →
Assignment of Assignor's Interest
May 2, 2013
From: COMPER, WAYNE; RAMACHANDRAN, APARNA; YAN, HAOHENG; RUSSO, LEILEATA M.
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 030336/0637 →
Assignment of Assignor's Interest
May 15, 2013
From: SKOG, JOHAN KARL OLOV; BERGHOFF, EMILY; LOGUIDICE, LORI
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 030425/0009 →
Assignment of Assignor's Interest
Jan 21, 2014
From: COMPER, WAYNE; RUSSO, LEILEATA M.; SKOG, JOHAN KARL OLOV
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 032006/0826 →
Employee Agreement
Feb 16, 2017
From: WEI, TAI-FEN
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 041736/0061 →
Assignment of Assignor's Interest
Feb 16, 2017
From: ENDERLE, DANIEL; RAMACHANDRAN, APARNA; YAN, HAOHENG; BERGHOFF, EMILY
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 041275/0826 →
Assignment of Assignor's Interest
Nov 14, 2017
From: OLOV SKOG, JOHAN KARL; RUSSO, LEILEATA
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 044114/0758 →
Assignment of Assignor's Interest
Jul 27, 2018
From: COMPER, WAYNE; RUSSO, LEILEATA M.; SKOG, JOHAN KARL OLOV
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 046483/0699 →
Assignment of Assignor's Interest
Nov 8, 2018
From: SKOG, JOHAN KARL OLOV; RUSSO, LEILEATA M
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 047454/0780 →
Assignment of Assignor's Interest
Mar 7, 2019
From: SKOG, JOHAN KARL OLOV; BERGHOFF, EMILY; LOGUIDICE, LORI
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 048530/0486 →
Assignment of Assignor's Interest
Apr 2, 2019
From: NOERHOLM, MIKKEL; BELZER, SUSAN; ROMAIN, CHARLOTTE; SKOG, JOHAN KARL OLOV
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 048762/0451 →
Assignment of Assignor's Interest
Apr 3, 2019
From: ENDERLE, DANIEL; RAMACHANDRAN, APARNA; YAN, HAOHEN; BERGHOFF, EMILY
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 048776/0937 →
Assignment of Assignor's Interest
Nov 19, 2019
From: SKOG, JOHAN KARL OLOV; ENDERLE, DANIEL; RAMACHANDRAN, APARNA; YAN, HAOHENG
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 051045/0679 →
Assignment of Assignor's Interest
Jan 28, 2022
From: NOERHOLM, MIKKEL; SKOG, JOHAN KARL OLOV; RUSSO, LEILEATA M.; COMPER, WAYNE
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 058813/0112 →
Assignment of Assignor's Interest
Feb 9, 2022
From: SKOG, JOHAN KARL OLOV; RUSSO, LEILEATA M.
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 058940/0034 →
Assignment of Assignor's Interest
Feb 6, 2023
From: ENDERLE, DANIEL; BERGHOFF, EMILY; NOERHOLM, MIKKEL; SKOG, JOHAN KARL OLOV
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 063902/0090 →
Assignment of Assignor's Interest
Jun 8, 2023
From: RAMACHANDRAN, APARNA; YAN, HAOHENG
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 063898/0310 →
Assignment of Assignor's Interest
Jun 8, 2023
From: WEI, TAI-FEN
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 063939/0636 →
Security Interest
Sep 29, 2025
From: EXOSOME DIAGNOSTICS, INC.
To: ORC SPV LLC
Reel/Frame 072403/0019 →
Release of Security Interest
Jan 13, 2026
From: ORC SPV LLC
To: EXOSOME DIAGNOSTICS, INC.
Reel/Frame 073452/0001 →