Antibodies to the polypeptide hormone phosphatonin
The present invention relates to a novel human protein called phosphatonin, and isolated polynucleotides encoding this protein. Also provided are vectors, host cells, antibodies, and recombinant methods for producing this human protein. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to this novel human protein.
1. An isolated antibody that binds specifically to a biologically active polypeptide having phosphatonin activity wherein the polypeptide comprises has an amino acid sequence with 90% or more amino acid sequence homology to the amino acid sequence of SEQ ID NO:27.
2. The antibody of claim 1 , wherein the polypeptide has an amino acid sequence of residues of 1 to 46 of SEQ ID NO:27.
3. The antibody of claim 1 , wherein the polypeptide has an amino acid sequence of residues of 1 to 96 of SEQ ID NO:27.
4. The antibody of claim 1 , wherein the polypeptide has an amino acid sequence of residues of 17 to 46 of SEQ ID NO:27.
5. The antibody of claim 1 , wherein the polypeptide has an amino acid sequence of residues of 17 to 96 of SEQ ID NO:27.
6. The antibody of claim 1 , wherein the polypeptide has an amino acid sequence of residues of 47 to 96 of SEQ ID NO:27.
7. The antibody of claim 1 , wherein the polypeptide has an amino acid sequence of residues of 47 to 525 of SEQ ID NO:27.
8. The antibody of claim 1 , wherein the polypeptide has an amino acid sequence of residues of 96 to 525 of SEQ ID NO:27.