IP Library Granted Patent US 8,153,814
Granted Patent B2
US 8,153,814 · App. 12/685,913 · Granted Apr 10, 2012

Sulfonamide derivatives

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Quick Facts
Patent No.
US 8,153,814
App. No.
12/685,913
Filed
Jan 12, 2010
Granted
Apr 10, 2012
Kind
B2
Art Unit
1625
USPC
548/190
Abstract

The present invention relates to compounds of the formula and pharmaceutically acceptable salts, solvates or tautomers thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds, and the uses of such compounds, in particular for the treatment of pain.

Claims (6)

1. 4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide, or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition comprising a compound of claim 1 , and one or more pharmaceutically acceptable excipients.

3. A pharmaceutical composition as claimed in claim 2 comprising one or more additional therapeutic agents.

4. A method of treating pain in a mammal comprising administering to a mammal requiring such treatment an effective amount of a compound of claim 1 .

5. The method according to claim 4 in which said pain is nociceptive.

6. The method according to claim 4 in which said pain is inflammatory.

Assignments (2)
FIRST AMENDMENT TO SECURITY AGREEMENT Recorded May 10, 2011
From: AXCELIS TECHNOLOGIES, INC.
To: SILICON VALLEY BANK
Reel/Frame 026250/0524 →
SECURITY AGREEMENT Recorded Apr 8, 2010
From: AXCELIS TECHNOLOGIES, INC.
To: SILICON VALLEY BANK
Reel/Frame 024202/0494 →