IP Library Granted Patent US 9,017,745
Granted Patent B2
US 9,017,745 · App. 12/832,944 · Granted Apr 28, 2015

Method of using isomaltulose to suppress body fat accumulation

Inventors: Jun Kashimura (Chigasaki, JP); Yukie Nagai (Chigasaki, JP); Tadashi Ebashi (Chigasaki, JP)
Assignee: Mitsui Sugar Co., Ltd.
A23L1/2363A21D2/181A23L1/307A23L2/60A23V2002/00A61K31/70
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Quick Facts
Patent No.
US 9,017,745
App. No.
12/832,944
Granted
Apr 28, 2015
Kind
B2
Abstract

A method for reducing body fat accumulation is provided that includes: providing a reducer of body fat accumulation, wherein the reducer comprises isomaltulose; having an individual ingest the reducer; and having the individual consume a carbohydrate having an α-1,6-glucosyl bond ratio of from 0% to less than 50% relative to the total bonds among constituent saccharides, wherein the reducer is ingested before or after or simultaneous with consuming the carbohydrate, and wherein the reducer reduces the individual's body fat accumulation caused by consuming the carbohydrate. The reducer of body fat accumulation includes isomaltulose (PALATINOSE™) as an active ingredient so that when the reducer is ingested and a carbohydrate having an α-1,6-glucosyl bond ratio of from 0% to less than 50% relative to the total bonds among constituent saccharides is consumed, accumulation of body fat resulting from ingesting the carbohydrate is reduced.

Claims (51)

1. A method for reducing body fat accumulation in a human resulting from an increase in blood glucose level and insulin secretion caused by consuming a food comprising carbohydrate selected from the group consisting of glucose, sucrose, high fructose corn syrup, starch, and dextrin, wherein the method comprises the steps of:

(a) providing a reducer of body fat accumulation, wherein the reducer comprises isomaltulose as an active ingredient;

(b) having a human individual ingest the reducer of body fat accumulation;

(c) having the human individual consume a food comprising the carbohydrate, wherein the reducer is ingested separately up to 30 minutes before consuming the food, or simultaneously with consuming the food, or separately after consuming the food within a time range within which the isomaltulose and carbohydrate can be mixed in the stomach, and wherein the carbohydrate has an α-1,6-glucosyl bond ratio of from 0% to less than 50% relative to the total bonds among constituent saccharides, and the isomaltulose is combined in the reducer so that the isomaltulose is ingested by the human individual in a dosed amount of 10 g or more per 60 Kg of body weight of the human individual; and

(d) selecting a time and amount of isomaltulose ingestion to reduce the increase in the human individual's body fat accumulation in response to ingesting the mixture of isomaltulose and carbohydrate, compared to the increase in the human individual's body fat accumulation that would otherwise occur if the carbohydrate were consumed alone.

2. A method for reducing body fat accumulation in a human resulting from an increase in blood glucose level and insulin secretion caused by consuming a carbohydrate selected from the group consisting of glucose, sucrose, high fructose corn syrup, starch and dextrin, wherein the method comprises the steps of:

(a) providing a reducer of body fat accumulation, wherein the reducer comprises isomaltulose as an active ingredient;

(b) having a human individual ingest the reducer of body fat accumulation;

(c) having the human individual consume the carbohydrate, wherein the reducer is ingested separately up to 30 minutes before consuming the carbohydrate, or simultaneously with consuming the carbohydrate, or separately after consuming the carbohydrate within a time range within which the isomaltulose and carbohydrate can be mixed in the stomach, and wherein the carbohydrate has an α-1,6-glucosyl bond ratio of from 0% to less than 50% relative to the total bonds among constituent saccharides, and the isomaltulose is combined in the reducer so that the isomaltulose is ingested by the human individual in a dosed amount of 10 g or more per 60 Kg of body weight of the human individual; and

(d) selecting a time and amount of isomaltulose ingestion to reduce the increase in the human individual's body fat accumulation in response to ingesting the mixture of isomaltulose and carbohydrate, compared to the increase in the human individual's body fat accumulation that would otherwise occur if the carbohydrate were consumed alone.

3. The method according to claim 1 , wherein the reducer is in the form of a powdery drink or tablet.

4. The method according to claim 1 , wherein weight of the isomaltulose has a ratio of 10% or more relative to the total weight of the carbohydrate.

5. The method according to claim 2 , wherein weight of the isomaltulose has a ratio of 10% or more relative to the total weight of carbohydrate.

6. The method according to claim 3 , wherein the reducer is the form of the powdery drink, and the powdery drink is selected from the group consisting of cocoa mix, a coffee, a powdery juice, a powdered black tea, a powdered lemonade, and an instant soup mix.

7. The method according to claim 1 , further comprising the step of reducing an increase in the human individual's blood glucose level in response to ingesting the mixture of carbohydrate and isomaltulose, compared to the increase in the human individual's blood glucose level that would otherwise occur if the carbohydrate were consumed alone.

8. A method for reducing body fat accumulation in a human resulting from an increase in blood glucose level and insulin secretion caused by consuming a food comprising a carbohydrate selected from the group consisting of glucose, sucrose, high fructose corn syrup, starch, and dextrin, wherein the method comprises the steps of:

(a) providing a reducer of body fat accumulation, wherein the reducer comprises isomaltulose as an active ingredient;

(b) having a human individual ingest the reducer of body fat accumulation;

(c) having the human individual consume a food comprising a carbohydrate, wherein the reducer is ingested separately up to 30 minutes before consuming the food, or simultaneously with consuming the food, or separately after consuming the food within a time range within which the isomaltulose and carbohydrate can be mixed in the stomach, and wherein the carbohydrate has an α-1,6-glucosyl bond ratio of from 0% to less than 50% relative to the total bonds among constituent saccharides, and wherein the food consumed includes 50 g to 150 g of the carbohydrate,

wherein the weight of the isomaltulose has a ratio of 20% or more relative to the total weight of the carbohydrate, and the isomaltulose is combined in the reducer so that the isomaltulose is ingested by the human individual in a dosed amount of 10 g or more per 60 Kg of body weight of the human individual; and

(d) selecting a time and amount of isomaltulose ingestion to reduce the increase in the human individual's body fat accumulation in response to ingesting the mixture of isomaltulose and carbohydrate, compared to the increase in the human individual's body fat accumulation that would otherwise occur if the carbohydrate were consumed alone.

9. A method for reducing body fat accumulation in a human resulting from an increase in blood glucose level and insulin secretion caused by consuming a carbohydrate selected from the group consisting of glucose, sucrose, high fructose corn syrup, starch, and dextrin, wherein the method comprises the steps of:

(a) providing a reducer of body fat accumulation, wherein the reducer comprises isomaltulose as an active ingredient;

(b) having a human individual ingest the reducer of body fat accumulation;

(c) having the human individual consume 50 g to 150 g of the carbohydrate, wherein the reducer is ingested separately up to 30 minutes before consuming the carbohydrate, or simultaneously with consuming the carbohydrate, or separately after consuming the carbohydrate within a time range within which the isomaltulose and carbohydrate can be mixed in the stomach, and wherein the carbohydrate has an α-1,6-glucosyl bond ratio of from 0% to less than 50% relative to the total bonds among constituent saccharides,

wherein the weight of the isomaltulose has a ratio of 20% or more relative to the total weight of the carbohydrate, and the isomaltulose is combined in the reducer so that the isomaltulose is ingested by the human individual in a dosed amount of 10 g or more per 60 Kg of body weight of the human individual; and

(d) selecting a time and amount of isomaltulose ingestion to reduce the increase in the human individual's body fat accumulation in response to ingesting the mixture of isomaltulose and carbohydrate, compared to the increase in the human individual's body fat accumulation that would otherwise occur if the carbohydrate were consumed alone.

10. The method according to claim 2 , further comprising the step of reducing an increase in the human individual's blood glucose level in response to ingesting the mixture of carbohydrate and isomaltulose, compared to the increase in the human individual's blood glucose level that would otherwise occur if the carbohydrate were consumed alone.

11. The method according to claim 8 , further comprising the step of reducing an increase in the human individual's blood glucose level in response to ingesting the mixture of carbohydrate and isomaltulose, compared to the increase in the human individual's blood glucose level that would otherwise occur if the carbohydrate were consumed alone.

12. The method according to claim 9 , further comprising the step of reducing an increase in the human individual's blood glucose level in response to ingesting the mixture of carbohydrate and isomaltulose, compared to the increase in the human individual's blood glucose level that would otherwise occur if the carbohydrate were consumed alone.

13. A method for reducing body fat accumulation in a human resulting from an increase in blood glucose level and insulin secretion caused by consuming a food comprising a carbohydrate selected from the group consisting of glucose, sucrose, high fructose corn syrup, starch and dextrin, wherein the method comprises the steps of:

(a) providing a reducer of body fat accumulation, wherein the reducer comprises isomaltulose as an active ingredient;

(b) having a human individual ingest the reducer of body fat accumulation;

(c) having the human individual consume a food comprising a carbohydrate, wherein the reducer is ingested substantially with the food, and wherein the carbohydrate has an α-1,6-glucosyl bond ratio of from 0% to less than 50% relative to the total bonds among constituent saccharides, and the isomaltulose is combined in the reducer so that the isomaltulose is ingested by the human individual in a dosed amount of 10 g or more per 60 Kg of body weight of the human individual; and

(d) selecting a time and amount of isomaltulose ingestion to reduce the increase in the human individual's body fat accumulation in response to ingesting the mixture of isomaltulose and carbohydrate, compared to the increase in the human individual's body fat accumulation that would otherwise occur if the carbohydrate were consumed alone.

14. A method for reducing body fat accumulation in a human resulting from an increase in blood glucose level and insulin secretion caused by consuming a carbohydrate selected from the group consisting of glucose, sucrose, high fructose corn syrup, starch and dextrin, wherein the method comprises the steps of:

(a) providing a reducer of body fat accumulation, wherein the reducer comprises isomaltulose as an active ingredient;

(b) having a human individual ingest the reducer of body fat accumulation;

(c) having the human individual consume the carbohydrate, wherein the reducer is ingested substantially with the carbohydrate, and wherein the carbohydrate has an α-1,6-glucosyl bond ratio of from 0% to less than 50% relative to the total bonds among constituent saccharides, and the isomaltulose is combined in the reducer so that the isomaltulose is ingested by the human individual in a dosed amount of 10 g or more per 60 Kg of body weight of the human individual; and

(d) selecting a time and amount of isomaltulose ingestion to reduce the increase in the human individual's body fat accumulation in response to ingesting the mixture of isomaltulose and carbohydrate, compared to the increase in the human individual's body fat accumulation that would otherwise occur if the carbohydrate were consumed alone.

15. A method for reducing body fat accumulation in a human resulting from an increase in blood glucose level and insulin secretion caused by consuming a food comprising a carbohydrate selected from the group consisting of glucose, sucrose, high fructose corn syrup, starch and dextrin, wherein the method comprises the steps of:

(a) providing a reducer of body fat accumulation, wherein the reducer comprises isomaltulose as an active ingredient;

(b) having a human individual ingest the reducer of body fat accumulation;

(c) having the human individual consume a food comprising the carbohydrate, wherein the reducer is ingested substantially with consuming the food, and wherein the carbohydrate has an α-1,6-glucosyl bond ratio of from 0% to less than 50% relative to the total bonds among constituent saccharides, and wherein the food consumed includes 50 g to 150 g of the carbohydrate, and the isomaltulose is combined in the reducer so that the isomaltulose is ingested by the human individual in a dosed amount of 10 g or more per 60 Kg of body weight of the human individual; and

(d) selecting a time and amount of isomaltulose ingestion to reduce the increase in the human individual's body fat accumulation in response to ingesting the mixture of isomaltulose and carbohydrate, compared to the increase in the human individual's body fat accumulation that would otherwise occur if the carbohydrate were consumed alone.

16. A method for reducing body fat accumulation in a human resulting from an increase in blood glucose level and insulin secretion caused by consuming a carbohydrate selected from the group consisting of glucose, sucrose, high fructose corn syrup, starch and dextrin, wherein the method comprises the steps of:

(a) providing a reducer of body fat accumulation, wherein the reducer comprises isomaltulose as an active ingredient;

(b) having a human individual ingest the reducer of body fat accumulation;

(c) having the human individual consume 50 g to 150 g of the carbohydrate, wherein the reducer is ingested substantially with consuming the carbohydrate, and wherein the carbohydrate has an α-1,6-glucosyl bond ratio of from 0% to less than 50% relative to the total bonds among constituent saccharides,

wherein the weight of the isomaltulose has a ratio of 10% or more relative to the total weight of the carbohydrate, and the isomaltulose is combined in the reducer so that the isomaltulose is ingested by the human individual in a dosed amount of 10 g or more per 60 Kg of body weight of the human individual; and

(d) selecting a time and amount of isomaltulose ingestion to reduce the increase in the human individual's body fat accumulation in response to ingesting the mixture of isomaltulose and carbohydrate, compared to the increase in the human individual's body fat accumulation that would otherwise occur if the carbohydrate were consumed alone.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 3, 2022
From: MITSUI DM SUGAR HOLDINGS CO., LTD.
To: MITSUI SUGAR CO., LTD.
Reel/Frame 059790/0286 →
CHANGE OF NAME Recorded Apr 14, 2022
From: MITSUI SUGAR CO., LTD.
To: MITSUI DM SUGAR HOLDINGS CO., LTD.
Reel/Frame 059719/0136 →
CHANGE OF NAME Recorded Apr 1, 2022
From: SHIN MITSUI SUGAR CO., LTD.
To: MITSUI SUGAR CO., LTD.
Reel/Frame 059572/0112 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 2, 2021
From: KASHIMURA, JUN; NAGAI, YUKIE; EBASHI, TADASHI
To: SHIN MITSUI SUGAR CO., LTD.
Reel/Frame 058264/0317 →
Priority Claims (3)
JP 2002-334032 · Nov 18, 2002 · national
JP 2003-096395 · Mar 31, 2003 · national
JP 2003-386594 · Nov 17, 2003 · national
Continuity (2)
Division 10715125 · Nov 18, 2003
Related Publication 20110009358A1 · Jan 13, 2011