Synbiotic mixture
View Patent ↗This invention relates to a preparation comprising N-acetyl-lactosamine and/or an oligosaccharide containing N-acetyl-lactosamine and a probiotic Lactobacillus sp. The invention extends to nutritional compositions comprising said preparation and to the use of the preparation in the prevention and treatment of pathogenic infections of the gastro-intestinal and upper respiratory tracts.
1. A composition selected from the group consisting of an infant formula and a growing up milk for treatment of pathogenic infections of a gastro-intestinal tract or an upper respiratory tract, the composition comprising:
lacto-N-neotetraose in an amount of 0.1 to 3% by dry weight of the composition; and
a probiotic Lactobacillus sp selected from the group consisting of (i) Lactobacillus rhamnosus CGMCC 1.3724 in an amount between 10 2 and 10 10 cfu for each gram of the lacto-N-neotetraose and (ii) Lactobacillus reuteri DSM 17938 in an amount between 10 2 and 10 10 cfu for each gram of the lacto-N-neotetraose.
2. The composition of claim 1 wherein the probiotic Lactobacillus sp is Lactobacillus rhamnosus CGMCC 1.3724.
3. The composition of claim 1 wherein the probiotic Lactobacillus sp is Lactobacillus reuteri DSM 17938.
4. The composition of claim 1 wherein the lacto-N-neotetraose is the only oligosaccharide containing N-acetyl-lactosamine in the composition.
5. A food product comprising 0.3 to 4% by weight based on dry matter of a component for treatment of pathogenic infections of a gastro-intestinal tract or an upper respiratory tract, the component comprising lacto-N-neotetraose in an amount of 0.1 to 3% by dry weight of the food product and further comprising a probiotic Lactobacillus sp selected from the group consisting of Lactobacillus rhamnosus CGMCC 1.3724 and Lactobacillus reuteri DSM 17938.