Mesh implant with an interlocking knitted structure

1. A resorbable polymeric mesh implant for use in reconstruction of soft tissue defects, wherein the mesh implant comprises:

a first set of resorbable polymeric fibers, and

a second set of resorbable polymeric fibers,

wherein the fibers are knitted together,

wherein filaments of said first set of fibers are interlaced into filaments of the second set of fibers and at least partly traverse a knit pattern of the second set of fibers such that the filaments of the first set of fibers lock the movement of the part of the mesh implant formed by the second set of fibers, and

wherein the relative distension of the mesh implant is substantially constant following the time of implantation and until said first set of fibers is substantially degraded, and

wherein the second set of resorbable polymeric fibers is substantially degraded at a later point in time than the first set of resorbable polymeric fibers,

wherein the second set of resorbable polymeric fibers is a fabric having a structural integrity without a presence of the first set of resorbable polymeric fibers,

wherein the first set of resorbable polymeric fibers and the second set of resorbable polymeric fibers have different patterns.

2. A resorbable polymeric mesh implant according to claim 1 , wherein the mesh implant comprises a third set of fibers that is substantially degraded at a later point in time than the second set of fibers and the relative distension of the mesh implant is substantially changed after the second set of fibers is substantially degraded.

3. A resorbable polymeric mesh implant according to claim 2 , wherein a first relative distention of the mesh implant following the time of implantation and until said first set of fibers is substantially degraded is within the range of 0-10%,

a third relative distention of the mesh implant following the substantial degradation of the first set of fibers and substantial degradation of the second set of fibers is greater than 20%, and

a second relative distention of the mesh implant following the substantial degradation of the first set of fibers but before the substantial degradation of the second set of fibers and the third set of fibers is greater than the first relative distention of the mesh implant and less than the third relative distention of the mesh implant.

4. A resorbable polymeric mesh implant according to claim 1 , wherein the relative distension of the mesh implant following the time of implantation and until said first set of fibers is substantially degraded is within the range of 0-10%.

5. A resorbable polymeric mesh implant according to claim 1 , wherein the relative distension of the mesh implant following the time of substantial degradation of the first set of fibers is above 10%.

6. A resorbable polymeric mesh implant according to claim 1 , wherein the polymeric mesh implant is a hernia mesh implant.

7. A resorbable polymeric mesh implant according to claim 1 , wherein the mesh implant stretches more in one direction along the plane of the mesh implant than in another direction along the plane of the mesh implant.

8. A resorbable polymeric mesh implant according to claim 1 , wherein the polymeric mesh implant is formed into a three-dimensional shape to support an internal body structure.

9. A resorbable polymeric mesh implant according to claim 1 , wherein the first set of fibers and/or further sets of fibers has or is incorporated into a knitted structure with an aperture size in the range of 0.1-4.0 mm.

10. A resorbable polymeric mesh implant according to claim 1 , wherein the mesh implant is knitted using a technique that produces a mesh that is resistant to runs.

11. A resorbable polymeric mesh implant according to claim 1 , wherein the mesh implant is fully resorbable.

12. A resorbable polymeric mesh implant according to claim 1 , wherein the first set of resorbable polymeric fibers is substantially degraded at a point in time within a time range of 5-30 days following implantation.

13. A resorbable polymeric mesh implant according to claim 1 , wherein the first set of resorbable polymeric fibers is substantially degraded at a point in time within a time range of 10-20 days following implantation.

14. A resorbable polymeric mesh implant according to claim 1 , wherein the second set of resorbable polymeric fibers is substantially degraded at a point in time within a time range of 6-12 months following implantation.

15. A resorbable polymeric mesh implant according to claim 1 , wherein the relative distension of the mesh implant following the time of implantation and until said first set of fibers is substantially degraded is within the range of 3-7%.

16. A resorbable polymeric mesh implant according to claim 1 , wherein the relative distension of the mesh implant following the substantial degradation of the first set of fibers is within the range of 15-25%.

17. A resorbable polymeric mesh implant according to claim 1 , wherein the last substantially degraded set of resorbable polymeric fibers has a knitted structure with an aperture size in the range of 0.2-2.0 mm.

18. A resorbable polymeric mesh implant according to claim 1 , wherein the first set of resorbable polymeric fibers is substantially degraded at a point in time within a time range of 2-40 days following implantation, and

wherein the last substantially degraded set of resorbable polymeric fibers is substantially degraded at a point in time within a time range of 3-18 months following implantation.

19. A resorbable polymeric mesh implant for use in reconstruction of soft tissue defects, comprising:

a first arrangement of resorbable material having a pattern and comprising fibers; and

a second arrangement of resorbable material having a pattern and comprising fibers, the second arrangement of resorbable material being substantially degradable at a later point in time than the first arrangement of resorbable material,

wherein the first arrangement of resorbable material is in contact with the second arrangement of resorbable material such that the first arrangement of resorbable material locks movement of the second arrangement of resorbable material by traversing apertures of the second arrangement of resorbable material to maintain relative distension of the mesh implant substantially constant following a time of implantation and until the first arrangement of resorbable material is substantially degraded,

wherein after the first arrangement of resorbable material is substantially degraded, the relative distension of the mesh implant substantially increases,

wherein the second arrangement is a fabric having a structural integrity without a presence of the first arrangement,

wherein the fibers of the first arrangement, until the first arrangement is substantially degraded, lock the pattern of the second arrangement by bridging points of the second arrangement, and

wherein, after the first arrangement is substantially degraded, fibers of the first arrangement no longer lock the pattern of the second arrangement and thereby permit the pattern of the second arrangement to open up and expand,

wherein the first arrangement of resorbable material and the second arrangement of resorbable material have different patterns.

20. A method to repair a soft tissue defect, wherein a resorbable polymeric mesh implant according to claim 19 is used.

21. A resorbable polymeric mesh implant according to claim 19 , wherein the polymeric mesh implant is a hernia mesh implant.

22. A resorbable polymeric mesh implant according to claim 19 , wherein the mesh implant is fully resorbable.

23. A resorbable polymeric mesh implant according to claim 19 , wherein the first arrangement of resorbable material is substantially degraded at a point in time within a time range of 5-30 days following implantation.

24. A resorbable polymeric mesh implant according to claim 19 , wherein the first arrangement of resorbable material is substantially degraded at a point in time within a time range of 10-20 days following implantation.

25. A resorbable polymeric mesh implant according to claim 19 , wherein the second arrangement of resorbable material is substantially degraded at a point in time within a time range of 6-12 months following implantation.

26. A resorbable polymeric mesh implant according to claim 19 , wherein the relative distension of the mesh implant following the time of implantation and until said first arrangement of resorbable material is substantially degraded is within the range of 3-7%.

27. A resorbable polymeric mesh implant according to claim 19 , wherein the relative distension of the mesh implant following the substantial degradation of the first arrangement of resorbable material is within the range of 15-25%.

28. A resorbable polymeric mesh implant according to claim 19 , wherein the last substantially degraded arrangement of fibers has a knitted structure with an aperture size in the range of 0.2-2.0 mm.

29. A resorbable polymeric mesh implant according to claim 19 , wherein the first arrangement of resorbable material is substantially degraded at a point in time within a time range of 2-40 days following implantation, and

wherein the last substantially degraded arrangement of resorbable material is substantially degraded at a point in time within a time range of 3-18 months following implantation.

30. A resorbable polymeric mesh implant according to claim 19 , wherein the first arrangement of resorbable material and the second arrangement of resorbable material are knitted together.

31. A resorbable polymeric mesh implant for use in reconstruction of soft tissue defects, comprising:

a first arrangement of resorbable material having a pattern and comprising fibers; and

a second arrangement of resorbable material having a pattern and comprising fibers, the second arrangement of resorbable material being substantially degradable at a later point in time than the first arrangement of resorbable material,

wherein the first arrangement of resorbable material is in contact with the second arrangement of resorbable material such that the first arrangement of resorbable material locks movement of the second arrangement of resorbable material by traversing pores of the second arrangement of resorbable material to maintain relative distension of the mesh implant substantially constant following a time of implantation and until the first arrangement of resorbable material is substantially degraded,

wherein after the first arrangement of resorbable material is substantially degraded, the relative distension of the mesh implant substantially increases,

wherein the second arrangement is a fabric having a structural integrity without a presence of the first arrangement,

wherein the fibers of the first arrangement, until the first arrangement is substantially degraded, constrain the pattern of the second arrangement by bridging points of the second arrangement thereby constraining pore size of the second arrangement, and

wherein, after the first arrangement is substantially degraded, fibers of the first arrangement no longer constrain the pattern of the second arrangement and thereby allow pore size of the second arrangement to increase.

32. A resorbable polymeric mesh implant according to claim 31 , wherein the first arrangement of resorbable material and the second arrangement of resorbable material are knitted together.

33. A resorbable polymeric mesh implant according to claim 31 , wherein the polymeric mesh implant is formed into a three-dimensional shape to support an internal body structure.