AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME

1 . A compound having the general formula (I) below:

in which

R3 and R4 may be, independently of each other:

1. H;

2. halogen;

3. CF 3 ;

4. substituted oxy;

5. optionally substituted alkoxy;

6. optionally substituted amino;

7. substituted carbonyl;

8. optionally substituted carboxyl;

9. optionally substituted amide;

10. sulfur in different oxidation states (II or IV or VI) such as optionally substituted sulfides, sulfoxides or sulfones;

11. C 1 -C 10 linear, branched or cyclic alkyl optionally comprising an optionally substituted heteroatom;

12. optionally substituted linear, branched or cyclic C 2 -C 7 alkenyl;

13. optionally substituted linear or branched C 2 -C 6 alkynyl;

14. optionally substituted aryl or heteroaryl;

15. optionally substituted heterocycloalkyl;

R6 being a heteroaryl (5- or 6-membered with 1 to 4 heteroatoms chosen from N, S and O) bonded to the azacarboline unit either via a C or via an N belonging to R6, R6 being optionally substituted; R6 also possibly representing C(O)NR1a R1b or an optionally substituted heterocycloalkyl or —C(O) optionally substituted heterocycloalkyl, such that R1a and R1b may be, independently of each other:

1. H;

2. optionally monosubstituted or disubstituted linear or branched or cyclic (C 3 -C 7 ) C 1 -C 10 alkyl;

3. optionally monosubstituted or disubstituted linear or branched C 2 -C 6 alkenyl;

4. optionally monosubstituted or disubstituted linear or branched C 2 -C 6 alkynyl;

5. optionally monosubstituted or disubstituted aryl;

6. optionally monosubstituted or disubstituted heteroaryl;

7. optionally monosubstituted or disubstituted benzyl;

8. optionally monosubstituted or disubstituted COalkyl;

9. optionally monosubstituted or disubstituted COaryl;

10. optionally monosubstituted or disubstituted COheteroaryl;

11. optionally monosubstituted or disubstituted CO2alkyl;

12. optionally monosubstituted or disubstituted CO2aryl;

13. optionally monosubstituted or disubstituted CO2heteroaryl;

14. CONH2;

15. optionally monosubstituted or disubstituted CONHalkyl;

16. optionally monosubstituted or disubstituted CONHaryl;

17. optionally monosubstituted or disubstituted CONHheteroaryl;

18. optionally monosubstituted or disubstituted CON(alkyl)2;

19. optionally monosubstituted or disubstituted CON(aryl)2;

20. optionally monosubstituted or disubstituted CON(heteroaryl)2;

the said products of formula (I) being in the form of the base or of an acid-addition salt.

2 . A compound of formula (I) as defined in claim 1 , in which

R3 and R4 may be, independently of each other:

1. H;

2. F;

3. Cl;

4. Br;

5. I;

6. CF 3 ;

7. OR2a;

8. NR1a R1b;

9. COR2a;

10. CO 2 R2a;

11. CO(NR1a R1b);

12. SR2a;

13. SOR2a;

14. SO 2 R2a;

15. linear or branched or cyclic (C 3 -C 7 ) C 1 -C 10 alkyl optionally monosubstituted or disubstituted or trisubstituted with R2a, R2b, R2c;

16. linear or branched or cyclic (C 3 -C 7 ) C 2 -C 6 alkenyl optionally monosubstituted or disubstituted or trisubstituted with R2a, R2b, R2c;

17. linear or branched C 2 -C 6 alkynyl optionally monosubstituted or disubstituted or trisubstituted with R2a, R2b, R2c;

18. aryl or heteroaryl optionally monosubstituted or disubstituted or trisubstituted with R2a, R2b, R2c;

19. heterocycloalkyl optionally monosubstituted or disubstituted or trisubstituted with R2a, R2b, R2c;

R6 being a heteroaryl (5- or 6-membered with 1 to 4 heteroatoms N, S or O) bonded to the azacarboline unit either via a C or an N belonging to R6, R6 also possibly representing C(O)NR1a R1b or an optionally substituted heterocycloalkyl or —C(O) optionally substituted heterocycloalkyl; R6 being optionally monosubstituted or disubstituted or trisubstituted with R2a, R2b, R2c;

in which:

R1a and R1b may be, independently of each other:

1. H;

2. linear or branched or cyclic (C 3 -C 7 ) C 1 -C 10 alkyl optionally monosubstituted or disubstituted with R2a R2b;

3. linear or branched C 2 -C 6 alkenyl optionally monosubstituted or disubstituted with R2a R2b;

4. linear or branched C 2 -C 6 alkynyl optionally monosubstituted or disubstituted with R2a R2b;

5. aryl optionally monosubstituted or disubstituted with R2a R2b;

6. heteroaryl optionally monosubstituted or disubstituted with R2a R2b;

7. benzyl optionally monosubstituted or disubstituted with R2a R2b;

8. COalkyl optionally monosubstituted or disubstituted with R2a R2b;

9. COaryl optionally monosubstituted or disubstituted with R2a R2b;

10. COheteroaryl optionally monosubstituted or disubstituted with R2a R2b;

11. CO 2 alkyl optionally monosubstituted or disubstituted with R2a R2b;

12. CO 2 aryl optionally monosubstituted or disubstituted with R2a R2b;

13. CO 2 heteroaryl optionally monosubstituted or disubstituted with R2a R2b;

14. CONH 2 ;

15. CONHalkyl optionally monosubstituted or disubstituted with R2a R2b;

16. CONHaryl optionally monosubstituted or disubstituted with R2a R2b;

17. CONHheteroaryl optionally monosubstituted or disubstituted with R2a R2b;

18. CON(alkyl) 2 optionally monosubstituted or disubstituted with R2a R2b;

19. CON(aryl) 2 optionally monosubstituted or disubstituted with R2a R2b;

20. CON(heteroaryl) 2 optionally monosubstituted or disubstituted with R2a R2b;

in which R2a, R2b and R2c are chosen, independently of each other, from:

1. F;

2. Cl;

3. Br;

4. I;

5. CF 3 ;

6. linear or branched C 1 -C 10 alkyl optionally monosubstituted or polysubstituted with different R3a;

7. C 3 -C 7 cycloalkyl optionally monosubstituted or polysubstituted with different R3a;

8. C 2 -C 6 alkenyl optionally monosubstituted or polysubstituted with different R3a;

9. C 2 -C 6 alkynyl optionally monosubstituted or polysubstituted with different R3a;

10. OH;

11. linear or branched O—(C 1 -C 10 )alkyl optionally monosubstituted or polysubstituted with different R3a;

12. O—(C 3 -C 7 )cycloalkyl optionally monosubstituted or polysubstituted with different R3a;

13. O-aryl optionally monosubstituted or polysubstituted with different R3a;

14. aryl optionally monosubstituted or polysubstituted with different R3a;

15. heteroaryl optionally monosubstituted or polysubstituted with different R3a;

16. heterocycloalkyl optionally monosubstituted or polysubstituted with different R3a;

17. NH 2 ;

18. NH—((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl), each group being optionally monosubstituted or polysubstituted with different R3a;

19. N((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl) 2 , each group being optionally monosubstituted or polysubstituted with different R3a;

20. NH-(aryl or heteroaryl) optionally monosubstituted or polysubstituted with different R3a;

21. N(aryl or heteroaryl) 2 , each group being optionally monosubstituted or polysubstituted with different R3a;

22. N(aryl or heteroaryl)((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl), each group being optionally monosubstituted or polysubstituted with different R3a;

23. NHC(O)R3a;

24. N((C 1 -C 10 )alkylC(O)R3a;

25. N(R3a)C(O)R3b;

26. NHS(O 2 )R3a;

27. N((C 1 -C 10 )alkylS(O 2 )R3a;

28. N(R3a)S(O) 2 R3b;

29. CO 2 R3a;

30. SR3a;

31. SOR3a;

32. SO 2 R3a;

in which R3a and R3b are chosen from:

1. halogen;

2. CF 3 ;

3. linear or branched C 1 -C 10 alkyl;

4. C 3 -C 7 cycloalkyl;

5. C 2 -C 6 alkenyl;

6. C 2 -C 6 alkynyl;

7. C 1 -C 10 alkylhydroxy;

8. C 1 -C 10 alkoxy;

9. C 1 -C 10 alkylamino;

10. OH;

11. linear, branched or cyclic (C 3 -C 7 ) O—(C 1 -C 10 )alkyl;

12. O-aryl;

13. aryl;

14. heteroaryl;

15. heterocycloalkyl;

16. NH 2 ;

17. NH—((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl);

18. N((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl) 2 ;

19. NH-(aryl or heteroaryl);

20. N(aryl or heteroaryl) 2 ;

21. N(aryl or heteroaryl)((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl);

22. NHC(O)—((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl);

23. NHC(O)-(aryl or heteroaryl);

24. NHS(O) 2 ((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl);

25. NHS(O) 2 -(aryl or heteroaryl);

26. CO (linear or branched C 1 -C 10 alkyl);

27. CO(C 1 -C 10 alkylamino);

28. CO 2 (linear or branched C 1 -C 10 alkyl);

29. C(O)NH (linear or branched C 1 -C 10 alkyl);

30. C(O)N (linear or branched C 1 -C 10 alkyl) 2 ;

31. S (linear or branched C 1 -C 10 alkyl);

32. SO (linear or branched C 1 -C 10 alkyl);

33. SO 2 (linear or branched C 1 -C 10 alkyl)

34. C(O)(heterocycloalkyl);

the said products of formula (I) being in the form of the base or of an acid-addition salt.

3 . A compound according to claim 1 , characterized in that:

R3 and R4 may be, independently of each other:

1. H;

2. F;

3. Cl;

4. Br;

5. I;

6. CF 3 ;

7. OR2a;

8. NR1aR1b;

9. COR2a;

10. CO 2 R2a;

11. CO(NR1aR1b);

12. SR2a;

13. SOR2a;

14. SO 2 R2a;

15. linear or branched or cyclic (C 3 -C 7 ) C 1 -C 10 alkyl optionally monosubstituted or disubstituted or trisubstituted with R2a, R2b, R2c;

16. linear or branched or cyclic (C 3 -C 7 ) C 2 -C 6 alkenyl optionally monosubstituted or disubstituted or trisubstituted with R2a, R2b, R2c;

17. linear or branched C 2 -C 6 alkynyl optionally monosubstituted or disubstituted or trisubstituted with R2a, R2b, R2c;

18. aryl or heteroaryl optionally monosubstituted or disubstituted or trisubstituted with R2a, R2b, R2c;

19. heterocycloalkyl optionally monosubstituted or disubstituted or trisubstituted with R2a, R2b, R2c;

R6 being a heteroaryl (5- or 6-membered with 1 to 4 heteroatoms N, S or O) bonded to the azacarboline unit either via a C or an N belonging to R6, R6 being optionally monosubstituted or disubstituted or trisubstituted with R2a, R2b, R2c;

in which:

R1a and R1b may be, independently of each other:

1. H;

2. linear or branched or cyclic (C 3 -C 7 ) C 1 -C 10 alkyl optionally monosubstituted or disubstituted with R2a R2b;

3. linear or branched C 2 -C 6 alkenyl optionally monosubstituted or disubstituted with R2a R2b;

4. linear or branched C 2 -C 6 alkynyl optionally monosubstituted or disubstituted with R2a R2b;

5. aryl optionally monosubstituted or disubstituted with R2a R2b;

6. heteroaryl optionally monosubstituted or disubstituted with R2a R2b;

7. benzyl optionally monosubstituted or disubstituted with R2a R2b;

8. COalkyl optionally monosubstituted or disubstituted with R2a R2b;

9. COaryl optionally monosubstituted or disubstituted with R2a R2b;

10. COheteroaryl optionally monosubstituted or disubstituted with R2a R2b;

11. CO 2 alkyl optionally monosubstituted or disubstituted with R2a R2b;

12. CO 2 aryl optionally monosubstituted or disubstituted with R2a R2b;

13. CO 2 heteroaryl optionally monosubstituted or disubstituted with R2a R2b;

14. CONH 2 ;

15. CONHalkyl optionally monosubstituted or disubstituted with R2a R2b;

16. CONHaryl optionally monosubstituted or disubstituted with R2a R2b;

17. CONHheteroaryl optionally monosubstituted or disubstituted with R2a R2b;

18. CON(alkyl) 2 optionally monosubstituted or disubstituted with R2a R2b;

19. CON(aryl) 2 optionally monosubstituted or disubstituted with R2a R2b;

20. CON(heteroaryl) 2 optionally monosubstituted or disubstituted with R2a R2b;

in which R2a, R2b and R2c are chosen, independently of each other, from:

1. F;

2. Cl;

3. Br;

4. I;

5, CF 3 ;

6. linear or branched C 1 -C 10 alkyl optionally monosubstituted or polysubstituted with different R3a;

7. C 3 -C 7 cycloalkyl optionally monosubstituted or polysubstituted with different R3a;

8. C 2 -C 6 alkenyl optionally monosubstituted or polysubstituted with different R3a;

9. C 2 -C 6 alkynyl optionally monosubstituted or polysubstituted with different R3a;

10. OH;

11. linear or branched O—(C 1 -C 10 )alkyl optionally monosubstituted or polysubstituted with different R3a;

12. O—(C 3 -C 7 )cycloalkyl optionally monosubstituted or polysubstituted with different R3a;

13. O-aryl optionally monosubstituted or polysubstituted with different R3a;

14. aryl optionally monosubstituted or polysubstituted with different R3a;

15. heteroaryl optionally monosubstituted or polysubstituted with different R3a;

16. heterocycloalkyl optionally monosubstituted or polysubstituted with different R3a;

17. NH 2 ;

18. NH—((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl), each group being optionally monosubstituted or polysubstituted with different R3a;

19. N((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl) 2 , each group being optionally monosubstituted or polysubstituted with different R3a;

20. NH-(aryl or heteroaryl) optionally monosubstituted or polysubstituted with different R3a;

21. N(aryl or heteroaryl) 2 , each group being optionally monosubstituted or polysubstituted with different R3a;

22. N(aryl or heteroaryl)((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl), each group being optionally monosubstituted or polysubstituted with different R3a;

23. NHC(O)R3a;

24. N((C 1 -C 10 )alkylC(O)R3a;

25. NHC(O)—((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl), each group being optionally monosubstituted or polysubstituted with different R3a;

26. NC(O)((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl) 2 , each group being optionally monosubstituted or polysubstituted with different R3a;

27. NHC(O)-(aryl or heteroaryl) optionally monosubstituted or polysubstituted with different R3a;

28. NC(O)(aryl or heteroaryl) 2 , each group being optionally monosubstituted or polysubstituted with different R3a;

29. NC(O)(aryl or heteroaryl)((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl), each group being optionally monosubstituted or polysubstituted with different R3a;

30. NHS(O 2 )R3a;

31. N((C 1 -C 10 )alkylS(O 2 )R3a;

32. NHS(O 2 )—((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl), each group being optionally monosubstituted or polysubstituted with different R3a;

33. NS(O 2 )((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl) 2 , each group being optionally monosubstituted or polysubstituted with different R3a;

34. NHS(O 2 )-(aryl or heteroaryl) optionally monosubstituted or polysubstituted with different R3a;

35. NS(O 2 )(aryl or heteroaryl) 2 , each group being optionally monosubstituted or polysubstituted with different R3a;

36. NS(O 2 )(aryl or heteroaryl)((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl), each group being optionally monosubstituted or polysubstituted with different R3a; COR3a;

37. CO 2 R3a;

38. SR3a;

39. SOR3a;

40. SO 2 R3a;

in which R3a is chosen from:

1. halogen;

2. CF 3 ;

3. linear or branched C 1 -C 10 alkyl;

4. C 3 -C 7 cycloalkyl;

5. C 2 -C 6 alkenyl;

6. C 2 -C 6 alkynyl;

7. OH;

8. linear, branched or cyclic (C 3 -C 7 ) O—(C 1 -C 10 )alkyl;

9. O-aryl;

10. aryl;

11. heteroaryl;

12. heterocycloalkyl;

13. NH 2 ;

14. NH((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl);

15. N((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl) 2 ;

16. NH-(aryl or heteroaryl);

17. N(aryl or heteroaryl) 2 ;

18. N(aryl or heteroaryl)((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl);

19. NHC(O)—((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl);

20. NC(O)((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl) 2 ;

21. NHC(O)-(aryl or heteroaryl);

22. NC(O)(aryl or heteroaryl) 2 ;

23. NC(O)(aryl or heteroaryl)((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl);

24. NHS(O 2 )—((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl);

25. NS(O 2 )((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl) 2 ;

26. NHS(O 2 )-(aryl or heteroaryl);

27. NS(O 2 )(aryl or heteroaryl) 2 ;

28. NS(O 2 )(aryl or heteroaryl)((C 1 -C 10 )alkyl or (C 3 -C 7 )cycloalkyl or heterocycloalkyl);

29. CO (linear or branched C 1 -C 10 alkyl);

30. CO 2 (linear or branched C 1 -C 10 alkyl);

31. C(O)NH (linear or branched C 1 -C 10 alkyl);

32. C(O)N (linear or branched C 1 -C 10 alkyl) 2 ;

33. S (linear or branched C 1 -C 10 alkyl);

34. SO (linear or branched C 1 -C 10 alkyl);

35. SO 2 (linear or branched C 1 -C 10 alkyl).

4 . A compound according to claim 1 , chosen from:

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfon-amide;

N-{4-[3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfon-amide;

4-(3,5-dimethoxyphenyl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-cyclopropyl-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-cyclopropyl-4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzenesulfonamide;

3-hydroxy-2,2-dimethylpropyl 6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxylate;

4-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenol;

4-[(E)-2-cyclopropylethenyl]-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-(3,5-difluorophenyl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

2-methylpropan-2-yl 6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxylate;

3-fluoro-4-iodo-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]butane-1,2-diol;

[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl](phenyl)methanone;

3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzenesulfonamide;

3-(morpholin-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(morpholin-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

2-methylpropyl 6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxylate;

N-methyl-N-propyl-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

ethyl 6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxylate;

6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-methyl-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-chloro-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-[(E)-2-phenylethenyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-chloro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-bromo-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

ethyl (2E)-3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]prop-2-enoate;

3-fluoro-4-[3-(morpholin-4-yl)phenyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxylic acid;

[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]methanol;

methyl 6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxylate;

N-methyl-N-propyl-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxamide;

3-fluoro-N-methyl-N-phenyl-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-4-carboxamide;

4-{methyl[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]amino}-1-(pyrrolidin-1-yl)butan-1-one;

6-(furan-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl](morpholin-4-yl)methanone;

6-(5-fluoropyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

2-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]propan-2-ol;

6-(6-fluoropyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N,N-diethyl-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

3-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-c: 5,4-c′]dipyridine;

1-chloro-N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methane-sulfonamide;

3-(4-methylpiperazin-1-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}cyclopropanesulfonamide;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methoxyphenyl}-methanesulfonamide;

N-{4-[3-fluoro-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}-methanesulfonamide;

3-fluoro-6-(5-methoxypyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(4-methoxypyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(1-benzyl-1 H-pyrazol-4-yl)-3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-[1-(2-methylpropyl)-1 H-pyrazol-4-yl]-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-[5-(methylsulfanyl)pyrid-3-yl]-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-ol;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-amine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-yl}-methanesulfonamide;

3-fluoro-4-[3-methyl-3-(piperazin-1-yl)but-1-yn-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

4-[3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-ol;

4-[3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-amine;

N-{4-[3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-yl}-methanesulfonamide;

3-methoxy-4-[3-methyl-3-(piperazin-1-yl)but-1-yn-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-[4-(4-methylpiperazin-1-yl)piperid-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

2-(4-{1-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]piperid-4-yl}piperazin-1-yl)ethanol;

3-fluoro-4-[4-(morpholin-4-yl)piperid-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-[4-(propan-2-yl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-(4-cyclopropylpiperazin-1-yl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-(4-ethylpiperazin-1-yl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-[4-(1-methylpiperid-4-yl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperid-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine:

2-(4-{1-[3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]piperid-4-yl}piperazin-1-yl)ethanol;

3-methoxy-4-[4-(morpholin-4-yl)piperid-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine:

3-methoxy-4-[4-(1-methylpiperid-4-yl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-methoxy-4-[4-(propan-2-yl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-(4-cyclopropylpiperazin-1-yl)-3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine:

4-(4-ethylpiperazin-1-yl)-3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-methoxy-4-[4-(methylsulfonyl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-fluoro-4-[4-(methylsulfonyl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine:

3-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}propanoic acid;

3-fluoro-4-(6-methoxypyrid-3-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfon-amide;

3-fluoro-4-(4-methylthiophen-2-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(1 H-indol-6-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

{2-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanol;

3-fluoro-4-(4-methylthiophen-3-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-N,N-dimethylaniline;

3-fluoro-4-(5-methylfuran-2-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(1-methyl-1 H-indol-5-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(1-methyl-1 H-pyrazol-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzyl}acetamide;

N-{3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzyl}methanesulfon-amide;

3-fluoro-4-(2-methoxyphenyl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-(2-ethoxypyrid-3-yl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-({3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}amino)-4-oxobutanoic acid;

N-{-4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzyl}methanesulfonamide;

{-4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}(morpholin-4-yl)methanone;

3-fluoro-4-(1-methyl-1 H-pyrazol-5-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

1-{2-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}-N,N-dimethyl-methanamine;

2-[3-fluoro-6-(pyrid-3-yl)-9,4-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzonitrile;

1-chloro-N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methane-sulfonamide;

3-(4-methylpiperazin-1-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}cyclopropanesulfonamide;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methoxyphenyl}-methanesulfonamide;

N-{4-[3-fluoro-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}-methanesulfonamide;

3-fluoro-6-(5-methoxypyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(4-methoxypyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(1-benzyl-1H-pyrazol-4-yl)-3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-[1-(2-methylpropyl)-1 H-pyrazol-4-yl]-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-[5-(methylsulfanyl)pyrid-3-yl]-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-{1-[2-(morpholin-4-yl)ethyl]-1H-pyrazol-4-yl}-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-[4-(propan-2-yl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(piperid-1-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-amine;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-ol;

4-[3-(4-ethylpiperazin-1-yl)-3-methylbut-1-yn-1-yl]-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}propanoic acid;

3-fluoro-4-(6-methoxypyrid-3-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfon-amide;

3-fluoro-4-(4-methylthiophen-2-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(1 H-indol-6-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

{2-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanol;

3-fluoro-4-(4-methylthiophen-3-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-N,N-dimethylaniline;

3-fluoro-4-(1-methyl-1H-indol-5-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzyl}acetamide;

N-{3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzyl}methanesulfonamide;

3-fluoro-4-(2-methoxyphenyl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-(2-ethoxypyrid-3-yl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-({3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}amino)-4-oxobutanoic acid;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzyl}methanesulfon-amide;

3-fluoro-4-(1-methyl-1 H-pyrazol-5-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}-2-methylpropanamide;

3-fluoro-4,6-di(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{2-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfon-amide;

3-fluoro-4-(1 H-pyrazol-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-[3-(methylsulfonyl)phenyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(2-methoxypyrimidin-5-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

5-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]pyrid-2-amine;

3-fluoro-4-[4-(1-methylpiperid-4-yl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-fluoro-4-[4-(morpholin-4-yl)piperid-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N,N-diethyl-2-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]piperazin-1-yl}-ethanamine;

3-fluoro-4-(4-methyl-1,4-diazepan-1-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

2-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]piperazin-1-yl}ethanol;

3-fluoro-4-[4-(4-methylpiperazin-1-yl)piperid-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}-N-methylmethane-sulfonamide;

3-(piperazin-1-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

4-(1.4′-bipiperid-1′-yl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

1-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-N,N-dimethylpiperid-4-amine;

3-fluoro-6-(pyrid-3-yl)-4-[4-(pyrrolidin-1-yl)piperid-1-yl]-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-{4-[3-(piperid-1-yl)propyl]piperazin-1-yl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-fluoro-4-{4-[3-(morpholin-4-yl)propyl]piperazin-1-yl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{-4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]piperazin-1-yl}-N,N-dipropylpropan-1-amine;

3-ethoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-iodo-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{1-[2-(morpholin-4-yl)ethyl]-1 H-pyrazol-4-yl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-(1-methyl-1H-pyrazol-3-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N,N-diethyl-3-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]piperazin-1-yl}-propan-1-amine;

N,N-diethyl-2-{4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]-1 H-pyrazol-1-yl}ethan-amine;

3-fluoro-4-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-[1-(2-methylpropyl)-1 H-pyrazol-4-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-[4-(morpholin-4-yl)phenyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-propyl-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

3-{4-[4-(propan-2-yl)piperazin-1-yl]phenyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(pyrid-3-yl)-3-(2,2,2-trifluoroethoxy)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-6-carbonitrile;

3-(2-methoxyethoxy)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{1-[3-(4-methylpiperazin-1-yl)propyl]-1 H-pyrazol-4-yl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

{3-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]phenyl}methanol;

N,N-diethyl-3-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]benzamide;

3-(3,5-dimethyl-1 H-pyrazol-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

2-{3,5-dimethyl-4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]-1 H-pyrazol-1-yl}-N,N-diethylethanamine;

3-methoxy-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

methyl 4-{6-[1-(prop-2-en-1-yl)-1 H-pyrazol-4-yl]-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl}benzoate;

N,N-diethyl-2-[4-(3-methoxy-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)-3,5-dimethyl-1 H-pyrazol-1-yl]ethanamine;

N-[2-(dimethylamino)ethyl]-2-[4-(3-methoxy-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)-1 H-pyrazol-1-yl]acetamide;

3-(1 H-pyrazol-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N,N-diethyl-3-{4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]-1 H-pyrazol-1-yl}-propan-1-amine;

N,N-diethyl-3-[4-(3-methoxy-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)-1 H-pyrazol-1-yl]propan-1-amine;

9H-pyrrolo[2,3-b:5,4-c′]dipyridine-6-carboxylic acid;

N-[3-(dimethylamino)propyl]-N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfonamide;

(4-methylpiperazin-1-yl)(9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)methanone;

5-[4-(3-methoxy-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)-1 H-pyrazol-1-yl]pentan-1-amine;

2-methyl-2-propyl {5-[4-(3-methoxy-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)-1 H-pyrazol-1-yl]-pentyl}carbamate;

3-methoxy-6-{1-[2-(1-methylpiperid-2-yl)ethyl]-1 H-pyrazol-4-yl}-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}-N,N-dimethylpropan-1-amine;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenol;

2-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}-N,N-dimethyl-ethanamine;

3-{1-[(1-ethylpyrrolidin-2-yl)methyl]-1H-pyrazol-4-yl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(pyrid-3-yl)-4-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-fluoro-6-(thiophen-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

2-methyl-2-propyl 4-{4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]-phenyl}piperazine-1-carboxylate;

3-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}-N,N,2-trimethyl-propan-1-amine;

3-fluoro-4-{4-[2-(morpholin-4-yl)ethoxy]phenyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

N,N-diethyl-2-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}ethan-amine;

N-[2-(dimethylamino)ethyl]-5-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5/4-c′]dipyrid-4-yl]-pyridine-2-carboxamide;

1-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}-3-(morpholin-4-yl)propan-2-ol;

N-ethyl-3-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}propan-1-amine;

4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]phenol;

3-[4-(piperazin-1-yl)phenyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(isoquinolin-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N,N-dimethyl-3-{4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]phenoxy}propan-1-amine;

3-{4-[3-(piperid-1-yl)propoxy]phenyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{4-[2-(morpholin-4-yl)ethoxy]phenyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{4-[3-(morpholin-4-yl)propoxy]phenyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{4-[2-(1H-imidazol-1-yl)ethoxy]phenyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-(4-{3-[4-(methylsulfonyl)piperazin-1-yl]propoxy}phenyl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N,N-diethyl-2-{3-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]phenoxy}ethanamine;

2-methyl-2-propyl 4-{3-[6-(pyrid-3-yl)-9H-pyrrolo dipyrid-3-yl]-phenyl}piperazine-1-carboxylate;

N,N,4-triethyl-5-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]pyrid-2-amine;

3-[3-(piperazin-1-yl)phenyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine hydrochloride;

N,N-diethyl-2-({4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-yl}oxy)ethanamine;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-N-(prop-2-en-1-yl)aniline;

N-(2-methylpropan-2-yl)-5-(9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)pyridine-3-carboxamide;

5-(3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)-N-(2-methylpropan-2-yl)pyridine-3 carboxamide;

3-fluoro-6-(1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

(2E)-N-[4-(dimethylamino)butyl]-3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]prop-2-enamide;

6-chloro-3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]phenoxy}propan-1-amine;

3-{1-[3-(4-methylpiperazin-1-yl)propyl]-1 H-pyrazol-4-yl}-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-[3-(4-methylpiperazin-1-yl)phenyl]-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

N,N-diethyl-2-{4-[6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]-1 H-pyrazol-1-yl}ethanamine;

6-(1-methyl-1 H-pyrazol-4-yl)-3-{4-[3-(morpholin-4-yl)propoxy]phenyl}-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N,N-diethyl-2-{3-[6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]-phenoxy}ethanamine;

3-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-4-{4-[3-(piperid-1-yl)propyl]piperazin-1-yl}-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-[3-(4-ethylpiperazin-1-yl)-3-methylbut-1-yn-1-yl]-3-fluoro-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-[3-(dimethylamino)propyl]-N-{4-[3-fluoro-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfonamide;

N-ethyl-3-{4-[3-fluoro-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}propan-1-amine;

N,N-diethyl-2-{4-[3-fluoro-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}ethanamine;

3-{4-[3-fluoro-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}-N,N,2-trimethylpropan-1-amine;

1-{4-[3-fluoro-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}-3-(piperid-1-yl)propan-2-ol;

1-{4-[3-(2-methoxyethoxy)-6-(1-methyl-1H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}-3-(piperid-1-yl)propan-2-ol;

3-(2-methoxyethoxy)-6-(1-methyl-1H-pyrazol-4-yl)-4-{4-[3-(piperid-1-yl)Propyl]piperazin-1-yl}-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-[3-(4-ethylpiperazin-1-yl)-3-methylbut-1-yn-1-yl]-3-(2-methoxyethoxy)-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-[3-(dimethylamino)propyl]-N-{4-[3-(2-methoxyethoxy)-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfonamide;

N-ethyl-3-{4-[3-(2-methoxyethoxy)-6-(1-methyl-1H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}propan-1-amine;

3-{4-[3-(2-methoxyethoxy)-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}-N,N,2-trimethylpropan-1-amine;

N,N-diethyl-2-{4-[3-(2-methoxyethoxy)-6-(1-methyl-1H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}ethanamine;

1-{4-[3-(2-methoxyethoxy)-6-(1-methyl-1H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}-3-(piperid-1-yl)propan-2-ol;

3-amino-1-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}pyrrolidine-2,5-dione;

4-({[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]oxy}methyl)-N,N-dimethylaniline;

3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl[4-(dimethylamino)phenyl]carbamate;

3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl[3-(dimethylamino)propyl]carbamate;

3-[(3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)carbonyl]-1.5.5-trimethylimidazolidine-2.4-dione;

3-[(3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)carbonyl]-1-methylimidazolidine-2.4-dione;

3-[(3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)carbonyl]-5,5-dimethyl-1-(propan-2-yl)imid-azolidine-2.4-dione;

1-[(3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)carbonyl]-4.4-dimethyl-3-(propan-2-yl)imid-azolidin-2-one;

1-[(3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)carbonyl]-3.4.4-trimethylimidazolidin-2-one;

1-[(3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)carbonyl]-3-methylimidazolidin-2-one;

3-fluoro-6-(1-methyl-1 H-imidazol-5-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-{1-methyl-5-[3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl]-1H-pyrazol-4-yl}-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(5-chloro-1-methyl-1H-pyrazol-4-yl)-3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(5-bromo-1-methyl-1H-pyrazol-4-yl)-3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{4-[3-(dimethylamino)propoxy]benzyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

N-{4-[2-(dimethylamino)ethoxy]benzyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

6-(pyrid-3-yl)-N-{[2-(pyrid-4-yl)cyclopropyl]methyl}-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

N-[3-fluoro-4-(piperazin-1-yl)benzyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

6-(pyrid-3-yl)-N-{[1-(pyrid-3-ylmethyl)-1 H-pyrrol-2-yl]methyl}-9H-pyrrolo[2,3-b:5,4-c′]-dipyrid-3-amine;

N-{4-[(dimethylamino)methyl]benzyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

4-methyl-N1-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]pentane-1,4-diamine;

N-(4-methyl-4-nitropentyl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b; 5,4-c′]dipyrid-3-amine;

N,N-dimethyl-N′[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]butane-1,4-diamine;

piperazin-1-yl[4-({[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]amino}methyl)phenyl]-methanone;

N-[4-(aminomethyl)benzyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

2-methyl-2-propyl[4-({[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]amino}methyl)-benzyl]carbamate;

2-methyl-2-propyl 4-{[4-({[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]amino}methyl)-phenyl]carbonyl}piperazine-1-carboxylate;

N-[4-(dimethylamino)benzyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

N-{4-[(4-methyl-1,4-diazepan-1-yl)methyl]benzyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyrid-3-amine;

4-(4-methyl-1,4-diazepan-1-yl)-N-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]benzamide;

N-[4-(4-methyl-1,4-diazepan-1-yl)benzyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

3-(4-methyl-1,4-diazepan-1-yl)-N-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]propanamide;

3-[(4-methyl-1,4-diazepan-1-yl)methyl]-N-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]benzamide;

N-{3-[(4-methyl-1,4-diazepan-1-yl)methyl]benzyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

N-[2-(4-methyl-1,4-diazepan-1-yl)ethyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carbonitrile;

6-(3,5-dimethyl-1 H-pyrazol-4-yl)-3-(pyrid-3-yl)-9H-3-carboline;

2-{3-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]phenoxy}ethanamine;

3-(4-{[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]oxy}phenyl)propan-1-ol;

N,N-dimethyl-2-(4-{[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]oxy}phenyl)ethan-amine;

2-(4-{[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]oxy}phenyl)acetamide;

N-methyl-2-(4-{[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]oxy}phenyl)acetamide;

N-cyclopropyl-2-(4-{[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]oxy}phenyl)acetamide;

N-(propan-2-yl)-1-(4-{[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]oxy}phenyl)propan-2-amine;

6-(pyrid-3-yl)-3-{4-[2-(pyrrolidin-1-yl)propyl]phenoxy}-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N,N-diethyl-3-(4-{[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]oxy}phenyl)propan-1-amine;

N,N-diethyl-2-{[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]oxy}ethanamine.

5 . A compound according to claim 1 , chosen from:

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfon-amide;

N-{-4-[3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfon-amide;

4-(3,5-dimethoxyphenyl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-cyclopropyl-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-cyclopropyl-4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzenesulfonamide;

3-hydroxy-2,2-dimethylpropyl 6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxylate;

4-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenol;

4-[(E)-2-cyclopropylethenyl]-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-(3,5-difluorophenyl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

2-methylpropan-2-yl 6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxylate;

3-fluoro-4-iodo-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]butane-1,2-diol;

[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl](phenyl)methanone;

3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzenesulfonamide;

3-(morpholin-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(morpholin-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

2-methylpropyl 6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxylate;

N-methyl-N-propyl-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

ethyl 6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxylate;

6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-methyl-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-chloro-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-[(E)-2-phenylethenyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-chloro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-bromo-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

ethyl (2E)-3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]prop-2-enoate;

3-fluoro-4-[3-(morpholin-4-yl)phenyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxylic acid;

[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]methanol;

methyl 6-(pyrid-3-yl)-9,4-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxylate;

N-methyl-N-propyl-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-3-carboxamide;

3-fluoro-N-methyl-N-phenyl-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-4-carboxamide;

4-{methyl[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]amino}-1-(pyrrolidin-1-yl)butan-1-one;

6-(furan-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl](morpholin-4-yl)methanone;

6-(5-fluoropyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

2-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]propan-2-ol;

6-(6-fluoropyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N,N-diethyl-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

3-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

1-chloro-N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methane-sulfonamide;

3-(4-methylpiperazin-1-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}cyclopropanesulfonamide;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methoxyphenyl}-methanesulfonamide;

N-{4-[3-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}-methanesulfonamide;

3-fluoro-6-(5-methoxypyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(4-methoxypyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(1-benzyl-1H-pyrazol-4-yl)-3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-[1-(2-methylpropyl)-1H-pyrazol-4-yl]-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-[5-(methylsulfanyl)pyrid-3-yl]-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-ol;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-amine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-yl}-methanesulfonamide;

3-fluoro-4-[3-methyl-3-(piperazin-1-yl)but-1-yn-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

4-[3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-YD-2-ol;

4-[3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-amine;

N-{4-[3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-yl}-methanesulfonamide;

3-methoxy-4-[3-methyl-3-(piperazin-1-yl)but-1-yn-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-[4-(4-methylpiperazin-1-yl)piperid-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

2-(4-{1-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]piperid-4-yl}piperazin-1-yl)ethanol;

3-fluoro-4-[4-(morpholin-4-yl)piperid-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-[4-(propan-2-yl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-(4-cyclopropylpiperazin-1-yl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-(4-ethylpiperazin-1-yl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-[4-(1-methylpiperid-4-yl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-methoxy-4-[4-(4-methylpiperazin-4-yl)piperid-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

2-(4-{1-[3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]piperid-4-yl}piperazin-1-yl)ethanol;

3-methoxy-4-[4-(morpholin-4-yl)piperid-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-methoxy-4-[4-(1-methylpiperid-4-yl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-methoxy-4-[4-(propan-2-yl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-(4-cyclopropylpiperazin-1-yl)-3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-(4-ethylpiperazin-1-yl)-3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-methoxy-4-[4-(methylsulfonyl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-fluoro-4-[4-(methylsulfonyl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}propanoic acid;

3-fluoro-4-(6-methoxypyrid-3-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfon-amide;

3-fluoro-4-(4-methylthiophen-2-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(1H-indol-6-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

{2-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanol;

3-fluoro-4-(4-methylthiophen-3-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-N,N-dimethylaniline;

3-fluoro-4-(5-methylfuran-2-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(1-methyl-1 H-indol-5-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(1-methyl-1 H-pyrazol-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzyl}acetamide;

N-[3-{3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzyl}methanesulfon-amide;

3-fluoro-4-(2-methoxyphenyl)-6-(pyrid-3-yl)-9,4-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-(2-ethoxypyrid-3-yl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-({3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}amino)-4-oxobutanoic acid;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzyl}methanesulfonamide;

{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}(morpholin-4-yl)methanone;

3-fluoro-4-(1-methyl-1 H-pyrazol-5-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

1-{2-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}-N,N-dimethyl-methanamine;

2-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzonitrile.

1-chloro-N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methane-sulfonamide;

3-(4-methylpiperazin-1-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}cyclopropanesulfonamide;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methoxyphenyl}-methanesulfonamide;

N-{4-[3-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfonamide;

3-fluoro-6-(5-methoxypyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(4-methoxypyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(1-benzyl-1 H-pyrazol-4-yl)-3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-[1-(2-methylpropyl)-1H-pyrazol-4-yl]-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-[5-(methylsulfanyl)pyrid-3-yl]-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-{1-[2-(morpholin-4-yl)ethyl]-1 H-pyrazol-4-yl}-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-[4-(propan-2-yl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(piperid-1-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-amine;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-ol;

4-[3-(4-ethylpiperazin-1-yl)-3-methylbut-1-yn-1-yl]-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}propanoic acid;

3-fluoro-4-(6-methoxypyrid-3-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfonamide;

3-fluoro-4-(4-methylthiophen-2-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(1H-indol-6-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

{2-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanol;

3-fluoro-4-(4-methylthiophen-3-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-N,N-dimethylaniline;

3-fluoro-4-(1-methyl-1H-indol-5-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(1-methyl-1 H-pyrazol-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzyl}acetamide;

N-{3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzyl}methanesulfonamide;

3-fluoro-4-(2-methoxyphenyl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-(2-ethoxypyrid-3-yl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

4-({3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}amino)-4-oxobutanoic acid;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]benzyl}methanesulfonamide;

3-fluoro-4-(1-methyl-1 H-pyrazol-5-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-C′]dipyrid-4-yl]phenyl}-2-methylpropanamide;

3-fluoro-4,6-di(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{2-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}methanesulfon-amide;

3-fluoro-4-(1 H-pyrazol-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-[3-(methyl sulfonyl)phenyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-(2-methoxypyrimidin-5-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

5-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]pyrid-2-amine;

3-fluoro-4-[4-(1-methylpiperid-4-yl)piperazin-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-fluoro-4-[4-(morpholin-4-yl)piperid-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N,N-diethyl-2-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]piperazin-1-yl}ethanamine;

3-fluoro-4-(4-methyl-1,4-diazepan-1-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

2-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]piperazin-1-yl}ethanol;

3-fluoro-4-[4-(4-methylpiperazin-1-yl)piperid-1-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenyl}-N-methylmethane-sulfonamide;

3-(piperazin-1-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

4-(1,4′-bipiperid-1′-yl)-3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

1-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-N,N-dimethylpiperid-4-amine;

3-fluoro-6-(pyrid-3-yl)-4-[4-(pyrrolidin-1-yl)piperid-1-yl]-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-4-{4-[3-(piperid-1-yl)propyl]piperazin-1-yl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-fluoro-4-{4-[3-(morpholin-4-yl)propyl]piperazin-1-yl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{-4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]piperazin-1-yl}-N,N-dipropylpropan-1-amine;

3-ethoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-iodo-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{1-[2-(morpholin-4-yl)ethyl]-1H-pyrazol-4-yl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-(1-methyl-1H-pyrazol-3-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N,N-diethyl-3-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]piperazin-1-yl}-propan-1-amine;

N,N-diethyl-2-{4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]-1H-pyrazol-1-yl}ethan-amine;

3-fluoro-4-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-[1-(2-methylpropyl)-1H-pyrazol-4-yl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-[4-(morpholin-4-yl)phenyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N-propyl-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-amine;

3-{4-[4-(propan-2-yl)piperazin-1-yl]phenyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

6-(pyrid-3-yl)-3-(2,2,2-trifluoroethoxy)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-6-carbonitrile;

3-(2-methoxyethoxy)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{1-[3-(4-methylpiperazin-1-yl)propyl]-1H-pyrazol-4-yl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

{3-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]phenyl}methanol;

N,N-diethyl-3-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]benzamide;

3-(3,5-dimethyl-1H-pyrazol-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

2-{3,5-dimethyl-4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]-1 H-pyrazol-1-yl}-N,N-diethylethanamine;

3-methoxy-6-(1-methyl-1 H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

methyl 4-{6-[1-(prop-2-en-1-yl)-1H-pyrazol-4-yl]-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl}benzoate;

N,N-diethyl-2-[4-(3-methoxy-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)-3,5-dimethyl-1 H-pyrazol-1-yl]ethanamine;

N-[2-(dimethylamino)ethyl]-2-[4-(3-methoxy-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)-1 H-pyrazol-1-yl]acetamide;

3-(1 H-pyrazol-4-yl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N,N-diethyl-3-{4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]-1 H-pyrazol-1-yl}-propan-1-amine;

N,N-diethyl-3-[4-(3-methoxy-9H-pyrrolo[2,3-b; 5,4-c′]dipyrid-6-yl)-1 H-pyrazol-1-yl]propan-1-amine;

9H-pyrrolo[2,3-b:5,4-c′]dipyridine-6-carboxylic acid;

N-[3-(dimethylamino)propyl]-N-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-C′]dipyrid-4-yl]phenyl}methanesulfonamide;

(4-methylpiperazin-1-yl)(9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)methanone;

5-[4-(3-methoxy-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)-1 H-pyrazol-1-yl]pentan-1-amine;

2-methyl-2-propyl {5-[4-(3-methoxy-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)-1 H-pyrazol-1-yl]pentyl}carbamate;

3-methoxy-6-{1-[2-(1-methylpiperid-2-yl)ethyl]-1 H-pyrazol-4-yl}-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-{-4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}-N,N-dimethylpropan-1-amine;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenol;

2-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}-N,N-dimethyl-ethanamine;

3-{1-[4(1-ethylpyrrolidin-2-yl)methyl]-1 H-pyrazol-4-yl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(pyrid-3-yl)-4-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

3-fluoro-6-(thiophen-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

2-methyl-2-propyl 4-{4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]-phenyl}piperazine-1-carboxylate;

3-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}-N,N,2-trimethyl-propan-1-amine;

3-fluoro-4-{4-[2-(morpholin-4-yl)ethoxy]phenyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine;

N,N-diethyl-2-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}ethan-amine;

N-[2-(dimethylamino)ethyl]-5-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-pyridine-2-carboxamide;

1-{4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}-3-morpholin-4-yl)propan-2-ol;

N-ethyl-3-{-4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]phenoxy}propan-1-amine;

4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]phenol;

3-[4-(piperazin-1-yl)phenyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-fluoro-6-(isoquinolin-4-yl)-9H-pyrrolo[2,3-b; 5,4-c′]dipyridine;

N,N-dimethyl-3-{4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b; 5,4-c′]dipyrid-3-yl]phenoxy}propan-1-amine;

3-{-4-[3-(piperid-1-yl)propoxy]phenyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{4-[2-(morpholin-4-yl)ethoxy]phenyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{4-[3-(morpholin-4-yl)propoxy]phenyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{4-[2-(1H-imidazol-1-yl)ethoxy]phenyl}-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-(4-{3-[4-(methyl sulfonyl)piperazin-1-yl]propoxy}phenyl)-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

N,N-diethyl-2-{3-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]phenoxy}ethanamine;

2-methyl-2-propyl 4-{3-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]-phenyl}piperazine-1-carboxylate;

N,N,4-triethyl-5-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]pyrid-2-amine;

3-[3-(piperazin-1-yl)phenyl]-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine hydrochloride;

N,N-diethyl-2-({4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-2-methylbut-3-yn-2-yl}oxy)ethanamine;

4-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]-N-(prop-2-en-1-yl)aniline;

N-(2-methylpropan-2-yl)-5-(9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)pyridine-3-carboxamide;

5-(3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-6-yl)-N-(2-methylpropan-2-yl)pyridine-3-carboxamide;

3-fluoro-6-(1H-pyrazol-4-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

(2E)-N-[4-(dimethylamino)butyl]-3-[3-fluoro-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-4-yl]prop-2-enamide;

6-chloro-3-fluoro-9H-pyrrolo[2,3-b:5,4-c′]dipyridine;

3-{4-[6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c′]dipyrid-3-yl]phenoxy}propan-1-amine.

6 . A pharmaceutical composition comprising the compound of claim 1 , or an addition salt of compound with a pharmaceutically acceptable acid.

7 . The pharmaceutical composition of claim 6 further comprising at least one pharmaceutically compatible excipient.

8 . A method for treating cancer in a patient in need thereof comprising administering to said patient a therapeutically effective amount of the pharmaceutical composition of claim 6 .

9 . A method of treating diseases that are sensitive to Pim kinase deregulation in a patient in need thereof comprising administering to said patient a therapeutically effective amount of the pharmaceutical composition of claim 6 .

10 . (canceled)

11 . (canceled)

12 . The compound of claim 1 wherein said compound is a kinase inhibitor.

13 . The compound of claim 1 wherein said compound is a Pim kinase inhibitors inhibitor.

14 . A process for synthesizing the compound of claim 1 having the following steps in Scheme 1 below:

in which the substituents R3 and R4 have the meanings given hereinabove or hereinbelow, and R represents either the values of R6 as defined above, or the following values: OH, OCH 3 , OS(O) 2 CF 3 , Cl, SCH 3 , CN.

15 . A compound having formula D3:

in which the substituents R3 and R4 have the meanings indicated in any one of claims 1 to 5 , and R represents the values of R6 as defined in any one of claims 1 to 5 and the following values: OH, OCH 3 , OS(O) 2 CF 3 , Cl, SCH 3 , CN.

16 . A compound having formula D3:

in which the substituent R3 represents a fluorine atom or a methoxy radical, and the substituent R4 represents a hydrogen atom, R being chosen from the values of R6 as defined in any one of claims 1 to 5 and the following values: OH, OCH 3 , OS(O) 2 CF 3 , Cl, SCH 3 , CN.

17 . A compound having formula D4:

in which the substituents R3 and R4 have the meanings indicated in any one of claims 1 to 5 and R represents the following values: OH, OCH 3 , OS(O) 2 CF 3 , Cl, SCH 3 , CN.