Plant derived seed extract rich in essential fatty acids derived from perilla seed: composition of matter, manufacturing process and use

1. A composition of matter comprising a shelf stable, supercritical, CO 2 fluid extracted seed oil derived from a cracked biomass of perilla frutescens , the seed oil comprising from 60 to 95 percent w/w of PUFAs in a ratio of from 4:1 to 6:1 alpha-linolenic acid (ALA) to linoleic acid (LA) and a mixture of selected antioxidants, wherein the perilla frutescens derived seed oil is made by subjecting the perilla frutescens seed to supercritical fluid CO2 extraction to produce a seed oil extract; fractionating the resulting seed oil extract in separate pressure step-down stages for collecting light and heavy fractions of seed oil extract; and separating the heavy fraction from the light fraction to form the final seed oil from the heavy fraction.

2. The composition of matter according to claim 1 , wherein the selected antioxidants comprise a mixture of selected lipophilic and hydrophilic antioxidants.

3. The composition of matter according to claim 1 , and further comprising lipophilic antioxidants either alone or in combination with at least one of: a) phenolic antioxidants including at least one of sage, oregano, and rosemary; b) tocopherol, c) tocotrienol(s), d) carotenoids including at least one of astaxanthin, lutein, and zeaxanthin; e) ascorbylacetate; f) ascorbylpalmitate g) Butylated hydroxytoluene (BHT); h) Docosapentaenoic Acid (BHA) or i) Tertiary Butyl hydroquinone (TBHQ).

4. The composition of matter according to claim 1 , and further comprising a hydrophilic antioxidant or sequesterant comprising hydrophilic phenolic antioxidants including at least one of grape seed extract, tea extracts, ascorbic acid, citric acid, tartaric acid, and malic acid.

5. The composition of matter according to claim 1 , wherein a peroxide value of the seed oil is under 10.0 meq/Km.

6. The composition of matter according to claim 1 , and further comprising docosahexaenoic acid (DHA) and/or eicosapentaenoic acid (EPA) in pectin or gelatin based confectionary dietary supplement delivery systems.

7. The composition of matter according to claim 1 , and further comprising EPA, DHA, docosapentaenoic acid (DPA) or gamma-linlolenic acid (GLA), fish oil, krill oil, krill oil concentrate, borage oil, evening primrose oil, olive oil or other plant, animal or algal based seed or fruit oils admixed therein.

8. The composition of matter according to claim 1 , and further comprising from 85 to 95 percent w/w of PUFAs.

9. The composition of matter according to claim 1 , wherein the PUFAs comprise at least greater than 56 percent alpha-linolenic acid (ALA).

10. The composition of matter according to claim 1 , wherein the seed oil is shelf stable at room temperature up to 32 months.

11. The composition of matter according to claim 1 , wherein said seed oil is derived from a premilled or flake-rolled cracked biomass of perilla frutescens.

12. A composition of matter comprising a shelf stable, supercritical, CO 2 fluid extracted seed oil derived from a cracked biomass of perilla frutescens , the seed oil comprising from 85 to 95 percent w/w of PUFAs in a ratio of from 4:1 to 6:1 alpha-linolenic acid (ALA) to linoleic acid (LA) and the PUFAs are greater than 50 percent ALA, and a mixture of selected antioxidants, including astaxanthin, phenolic antioxidants and natural tocopherols, wherein the perilla frutescens derived seed oil is made by subjecting the perilla frutescens seed to supercritical fluid CO2 extraction to produce a seed oil extract; fractionating the resulting seed oil extract in separate pressure step-down stages for collecting light and heavy fractions of seed oil extract; and separating the heavy fraction from the light fraction to form the final seed oil from the heavy fraction.

13. The composition of matter according to claim 12 , comprising at least one of dispersed nano- and micro-particles of rice or sugar cane based policosanol.

14. The composition of matter according to claim 12 , and further comprising lipophilic antioxidants either alone or in combination with at least one of: a) phenolic antioxidants including at least one of sage, oregano, and rosemary; b) tocopherol, c) tocotrienol(s), d) carotenoids including at least one of astaxanthin, lutein, and zeaxanthin; e) ascorbylacetate; f) ascorbylpalmitate g) Butylated hydroxytoluene (BHT); h) Docosapentaenoic Acid (BHA) or i) Tertiary Butyl hydroquinone (TBHQ).

15. The composition of matter according to claim 12 , and further comprising a hydrophilic antioxidant or sequesterant comprising hydrophilic phenolic antioxidants including at least one of grape seed extract, tea extracts, ascorbic acid, citric acid, tartaric acid, and malic acid.

16. The composition of matter according to claim 12 , wherein a peroxide value of the seed oil is under 10.0 meq/Km.

17. The composition of matter according to claim 12 , and further comprising docosahexaenoic acid (DHA) and/or eicosapentaenoic acid (EPA) in pectin or gelatin based confectionary dietary supplement delivery systems.

18. The composition of matter according to claim 12 , and further comprising EPA, DHA, docosapentaenoic acid (DPA) or gamma-linlolenic acid (GLA), fish oil, krill oil, krill oil concentrate, borage oil, evening primrose oil, olive oil or other plant, animal or algal based seed or fruit oils admixed therein.

19. The composition of matter according to claim 12 , wherein the PUFAs comprise at least greater than 56 percent alpha-linolenic acid (ALA).

20. The composition of matter according to claim 12 , wherein the seed oil is shelf stable at room temperature up to 32 months.

21. The composition of matter according to claim 12 , wherein said seed oil is derived from a premilled or flake-rolled cracked biomass of perilla frutescens.