IP Library Granted Patent US 8,383,680
Granted Patent B2
US 8,383,680 · App. 13/275,996 · Granted Feb 26, 2013

Composition comprising free amino acids

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Quick Facts
Patent No.
US 8,383,680
App. No.
13/275,996
Granted
Feb 26, 2013
Kind
B2
Abstract

A method is provided for the prevention and treatment of patients having impaired gastro-intestinal tract function. The method comprises the steps of administering to a patient requiring same free amino acids including about 9.0% to about 17.0% glutamic acid.

Claims (107)

1. A method of providing nutrition to an individual at risk of having impaired gastro-intestinal tract function comprising the steps of administering a therapeutically effective amount of a composition which comprises free amino acids and about 9.0% to about 17.0% glutamic acid by weight of total amino acid composition, wherein the composition has no glutamine, and wherein the composition comprises methionine in an amount from about 2.4 to about 3.2 g/100 g total amino acids.

2. The method according to claim 1 , wherein the composition comprises cysteine in an amount from about 2.3 to about 10 g.

3. The method according to claim 1 , wherein the impaired gastro-intestinal function is due to Crohn's disease, cystic fibrosis, HIV/AIDS, cancer, post surgery complications, intractable diarrhoea, short bowel syndrome, cerebral palsy or gastric reflux.

4. The method according to claim 1 , wherein the composition is in a ready to use form.

5. The method according to claim 1 , wherein the composition comprises arginine in an amount from 2.3% to 7% total amino acids by weight.

6. The method according to claim 1 , wherein the composition comprises aspartic acid.

7. The method according to claim 1 , wherein the composition comprises leucine.

8. The method according to claim 1 , wherein the composition comprises threonine.

9. The method according to claim 1 , wherein the composition comprises proline.

10. The method according to claim 1 , wherein the composition comprises tryptophan.

11. The method according to claim 1 , wherein the composition comprises serine.

12. The method of claim 1 , wherein the composition comprises lysine.

13. The method of claim 1 , wherein the composition comprises branched amino acids.

14. The method of claim 1 , wherein the composition further comprises at least one amino acid in the following amounts selected from the group consisting of:

Amount

Amino

(g/100 g total

Acids

amino acids)

Ile

5.7-7.0

Leu

10.8-14.0

Lys

 6.5-10.0

Phe

3.2-.2 

Thr

 5.0-12.0

Trp

1.7-2.2

Val

5.5-7.0

His

1.8-2.3

Arg

2.3-7.0

Pro

5.0-6.0

Gly

1.9-3.2

Ala

1.5-5.1

Ser

 5.0-16.0

Tyr

1.0-4.0

Cys

 2.3-10.0

Asp

 4.0-15.0

Aromatics

 4.2-11.2

Sulphur

 4.7-13.2

containing

BCAA

 22.0-28.0.

15. The method of claim 1 , wherein the composition comprises:

Amount

Amino

(g/100 g total

Acids

amino acids)

Ile

5.7-7.0

Leu

10.8-14.0

Lys

 6.5-10.0

Met

2.4-3.2

Phe

3.2-.2 

Thr

 5.0-12.0

Trp

1.7-2.2

Val

5.5-7.0

His

1.8-2.3

Arg

2.3-7.0

Pro

5.0-6.0

Gly

1.9-3.2

Ala

1.5-5.1

Ser

 5.0-16.0

Tyr

1.0-4.0

Cys

 2.3-10.0

Asp

 4.0-15.0

Glu

 9.0-17.0

Aromatics

 4.2-11.2

Sulphur

 4.7-13.2

containing

BCAA

 22.0-28.0.

Assignments (5)
CORRECTIVE ASSIGNMENT TO CORRECT THE PATENT NUMBER 16062921 PREVIOUSLY RECORDED ON REEL 049391 FRAME 0756. ASSIGNOR(S) HEREBY CONFIRMS THE PATENT NUMBER SHOULD HAVE BEEN 16062912. Recorded Jul 3, 2020
From: NESTEC S.A.
To: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Reel/Frame 054082/0001 →
CORRECTIVE ASSIGNMENT TO CORRECT THE PATENT NUMBER 16062921 PREVIOUSLY RECORDED ON REEL 049391 FRAME 0756. ASSIGNOR(S) HEREBY CONFIRMS THE PATENT NUMBER SHOULD HAVE BEEN 16062912. Recorded Jul 3, 2020
From: NESTEC S.A.
To: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Reel/Frame 054082/0165 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ENGLISH TRANSLATION TO SHOW THE FULL AND CORRECT NEW NAME IN SECTION 51. PREVIOUSLY RECORDED AT REEL: 049391 FRAME: 0756. ASSIGNOR(S) HEREBY CONFIRMS THE MERGER. Recorded Jun 13, 2019
From: NESTEC S.A.
To: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Reel/Frame 049853/0398 →
MERGER Recorded Jun 6, 2019
From: NESTEC S.A.
To: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Reel/Frame 049391/0756 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 20, 2011
From: WHIPPIE, CONSTANCE; BALLEVRE, OLIVIER; BOZA, JULIO; FINOT, PAUL-ANDRE
To: NESTEC S.A.
Reel/Frame 027093/0067 →