IP Library Granted Patent US 8,580,806
Granted Patent B2
US 8,580,806 · App. 13/747,052 · Granted Nov 12, 2013

Salts of 4-methyl N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide

Inventors: Paul W Manley (Arlesheim, CH); Wen-Chung Shieh (Berkeley Heights, NJ); Paul Allen Sutton (Parsippany, NJ); Piotr H Karpinski (Lincoln Park, NJ); Raeann Wu (Pine Brook, NJ); Stéphanie Monnier (Raedersheim, FR); Jörg Brozio (Basel, CH)
Assignee: Novartis AG
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,580,806
App. No.
13/747,052
Granted
Nov 12, 2013
Kind
B2
Abstract

Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide are prepared by various processes.

Claims (2)

1. A method of treating blast crisis chronic myelogenous leukemia comprising the step of administering to a subject in need thereof, a therapeutically effective amount of a salt, 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzeneamide monohydrochloride monohydrate.

2. A method of treating Philadelphia chromosome positive chronic myelogenous leukemia comprising the step of administering to a subject in need thereof, a therapeutically effective amount of a salt, 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzeneamide monohydrochloride monohydrate.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 22, 2013
From: MANLEY, PAUL W; SHIEH, WEN-CHUNG; SUTTON, PAUL ALLEN; KARPINSKI, PIOTR H; WU, RAEANN; MONNIER, STEPHANIE; BROZIO, JORG
To: NOVARTIS AG
Reel/Frame 031061/0959 →
Continuity (5)
Division 13419132 · Mar 13, 2012
Division 11995898
Provisional Application 60701406 · Jul 20, 2005
Provisional Application 60716213 · Sep 12, 2005
Related Publication 20130137712A1 · May 30, 2013