IP Library Granted Patent US 8,921,092
Granted Patent B2
US 8,921,092 · App. 13/765,671 · Granted Dec 30, 2014

System and method for electroporating a sample

Inventors: Richard Jarvis (Austin, TX); Mike Byrom (Austin, TX); Dmitriy Ovcharenko (Austin, TX)
Assignee: Applied Biosystems LLC
C12M45/07C12M35/02C12N15/86A61K48/00C12N2710/16632C12N2710/16643C12N2830/00C12N2830/008
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Quick Facts
Patent No.
US 8,921,092
App. No.
13/765,671
Granted
Dec 30, 2014
Kind
B2
Abstract

A system and method are described for electroporating a sample that utilizes one or more sets of electrodes that are spaced apart in order to hold a surface tension constrained sample between the electrodes. The first electrode is connected to the lower body of the system while the second electrode is connected to the upper body. Both electrodes are connected to a pulse generator. Each electrode has a sample contact surface such that the first electrode and the second electrode may be positioned to hold a surface tension constrained sample between the two sample contact surfaces and the sample may receive a selected electric pulse.

Claims (10)

1. An electrode array system for electroporation comprising:

a plurality of sample contact surfaces, each of the plurality of sample contact surfaces operable to hold an electroporation sample;

the plurality of sample contact surfaces electrically connected to receive an electric pulse from a pulse generator wherein the electric connection is operable to provide electric current to electroporate the electroporation sample present on each of the sample contact surfaces;

the plurality of sample contact surfaces disposed on an electrode base; and the plurality of sample contact surfaces associated with a corresponding electrode array.

2. The electrode array system of claim 1 wherein the electrode base is a 96 sample base.

3. The electrode array system of claim 1 , further comprising one or more component selected from a monitoring system, a computer system and computer software.

4. The electrode array system of claim 1 , wherein the shape of the sample contact surfaces is flat.

5. The electrode array system of claim 1 , wherein the shape of the sample contact surfaces is circular.

6. The electrode array system of claim 1 , wherein the shape of the sample contact surfaces is non-flat.

7. The electrode array system of claim 1 , wherein the shape of the sample contact surfaces is non-circular.

Assignments (5)
MERGER Recorded May 7, 2013
From: APPLERA CORPORATION
To: APPLIED BIOSYSTEMS INC.
Reel/Frame 030362/0783 →
MERGER Recorded May 7, 2013
From: ATOM ACQUISITION CORPORATION
To: APPLIED BIOSYSTEMS INC.
Reel/Frame 030362/0829 →
MERGER Recorded May 7, 2013
From: APPLIED BIOSYSTEMS INC. & ATOM ACQUISITION, LLC
To: APPLIED BIOSYSTEMS, LLC
Reel/Frame 030362/0858 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 19, 2013
From: JARVIS, RICHARD A.; BYROM, MIKE W.; OVCHARENKO, DMITRIY
To: AMBION, INC.
Reel/Frame 030252/0058 →
MERGER Recorded Apr 19, 2013
From: AMBION, INC.
To: APPLERA CORPORATION
Reel/Frame 030252/0208 →
Continuity (5)
Continuation 12760526 · Apr 14, 2010
Continuation 12123619 · May 20, 2008
Division 11130884 · May 17, 2005
Continuation 10863102 · Jun 8, 2004
Related Publication 20140057337A1 · Feb 27, 2014