IP Library › Granted Patent US 9,156,888
Granted Patent B2
US 9,156,888 · App. 13/951,679 · Granted Oct 13, 2015

Antibody molecules

Inventors: Patrick S. Moore (Pittsburgh, PA); Yuan Chang (Pittsburgh, PA); Huichen Feng (Pittsburgh, PA)
Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
C07K14/005C07K16/084C12N7/00C12Q1/18G01N33/56983G01N33/574G01N33/6893A61K2039/5258C12N2710/22022C12N2710/22023
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Quick Facts
Patent No.
US 9,156,888
App. No.
13/951,679
Granted
Oct 13, 2015
Kind
B2
Abstract

The present invention provides murine monoclonal antibody molecules that bind to Merkel cell carcinoma virus (MCV) polypeptides.

Claims (25)

1. An isolated or substantially purified murine monoclonal antibody molecule that binds selectively to a polypeptide consisting essentially of an amino acid sequence selected from the group of sequences consisting of SEQ ID NOs: 6, 8, 10, 12, 14, 16, 18, 20, and any open reading frame (ORF) of SEQ ID NOs: 1-4.

2. The antibody molecule of claim 1 , wherein the polypeptide consists essentially of the amino acid sequence of SEQ ID NO:6.

3. The antibody molecule of claim 1 , wherein the polypeptide consists of the amino acid sequence of SEQ ID NO:6.

4. The antibody molecule of claim 1 , wherein the polypeptide consists essentially of the amino acid sequence of SEQ ID NO:8.

5. The antibody molecule of claim 1 , wherein the polypeptide consists of the amino acid sequence of SEQ ID NO:8.

6. The antibody molecule of claim 1 , wherein the polypeptide consists essentially of the amino acid sequence of SEQ ID NO:10.

7. The antibody molecule of claim 1 , wherein the polypeptide consists of the amino acid sequence of SEQ ID NO:10.

8. The antibody molecule of claim 1 , wherein the polypeptide consists essentially of the amino acid sequence of SEQ ID NO:12.

9. The antibody molecule of claim 1 , wherein the polypeptide consists of the amino acid sequence of SEQ ID NO:12.

10. The antibody molecule of claim 1 , wherein the polypeptide consists essentially of the amino acid sequence of SEQ ID NO:14.

11. The antibody molecule of claim 1 , wherein the polypeptide consists of the amino acid sequence of SEQ ID NO:14.

12. The antibody molecule of claim 1 , wherein the polypeptide consists essentially of the amino acid sequence of SEQ ID NO:16.

13. The antibody molecule of claim 1 , wherein the polypeptide consists of the amino acid sequence of SEQ ID NO:16.

14. The antibody molecule of claim 1 , wherein the polypeptide consists essentially of the amino acid sequence of SEQ ID NO:18.

15. The antibody molecule of claim 1 , wherein the polypeptide consists of the amino acid sequence of SEQ ID NO:18.

16. The antibody molecule of claim 1 , wherein the polypeptide consists essentially of the amino acid sequence of SEQ ID NO:20.

17. The antibody molecule of claim 1 , wherein the polypeptide consists of the amino acid sequence of SEQ ID NO:20.

18. The antibody molecule of claim 1 , wherein the polypeptide consists essentially of the amino acid sequence of an ORF of SEQ ID NO:1.

19. The antibody molecule of claim 1 , wherein the polypeptide consists of the amino acid sequence of an ORF of SEQ ID NO:1.

20. The antibody molecule of claim 1 , wherein the polypeptide consists essentially of the amino acid sequence of an ORF of SEQ ID NO:2.

21. The antibody molecule of claim 1 , wherein the polypeptide consists of the amino acid sequence of an ORF of SEQ ID NO:2.

22. The antibody molecule of claim 1 , wherein the polypeptide consists essentially of the amino acid sequence of an ORF of SEQ ID NO:3.

23. The antibody molecule of claim 1 , wherein the polypeptide consists of the amino acid sequence of an ORF of SEQ ID NO:3.

24. The antibody molecule of claim 1 , wherein the polypeptide consists essentially of the amino acid sequence of an ORF of SEQ ID NO:4.

25. The antibody molecule of claim 1 , wherein the polypeptide consists of the amino acid sequence of an ORF of SEQ ID NO:4.

Assignments (1)
CONFIRMATORY LICENSE Recorded Sep 6, 2013
From: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 031171/0101 →
Continuity (3)
Division 12808042
Provisional Application 61013772 · Dec 14, 2007
Related Publication 20140037581A1 · Feb 6, 2014