IP Library Granted Patent US 10,226,405
Granted Patent B2
US 10,226,405 · App. 13/968,862 · Granted Mar 12, 2019

Purified polyurea capsules, methods of preparation, and products containing the same

Inventors: Yabin Lei (Holmdel, NJ); Li Xu (Newark, NJ); Carol Joyce (Toms River, NJ)
Assignee: International Flavors & Fragrances Inc.
A61K8/11A61K8/34A61K8/84A61Q5/02A61Q5/12A61Q13/00A61Q15/00A61Q19/10B01J13/14B01J13/16B01J13/20C11D3/505C11D17/0039A61K2800/412
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Quick Facts
Patent No.
US 10,226,405
App. No.
13/968,862
Granted
Mar 12, 2019
Kind
B2
Abstract

Purified polyurea capsules that encapsulate active materials for use in personal care, fine fragrance, or deodorant products are provided as are methods for producing the same.

Claims (24)

1. A method for preparing a purified polyurea capsule composition comprising:

(a) preparing an oil phase comprising an active material and at least one polyisocyanate;

(b) preparing an aqueous phase;

(c) emulsifying the oil phase into the aqueous phase to form a fragrance emulsion;

(d) adding at least one cross-linking agent to the fragrance emulsion to form a polyurea capsule slurry;

(e) curing the polyurea capsule slurry;

(f) adding a salt solution to the polyurea capsule; and

(g) washing the polyurea capsule slurry with water until a neutral pH is achieved,

wherein the polyurea capsule slurry contains (i) 10 to 60% the active material, (ii) 1 to 7.5% of the polyisocyanate, (iii) 0.1 to 5% the cross-linking agent, and (iv) 0.5 to 4% of a capsule formation aid,

the polyisocyanate is an aromatic polyisocyanate, and

the capsule formation aid is a sulfonated naphthalene-formaldehyde condensate or a sulfonated polystyrene.

2. The method of claim 1 , wherein the active material is a fragrance oil.

3. The method of claim 1 , wherein the polyisocyanate is 4,4′-diphenylmethane diisocyanate, or a compound of the following structure:

in which n is 0 to 6.

4. The method of claim 3 , wherein the active material is a fragrance oil.

5. The method of claim 3 , wherein the cross-linking agent is hexamethylenediamine or polyethyleneimine.

6. The method of claim 1 , wherein the salt solution is a solution of sodium chloride, potassium chloride, or a bi-sulphite salt.

7. The method of claim 6 , wherein the cross-linking agent is hexamethylenediamine or polyethyleneimine.

8. The method of claim 6 , wherein the polyisocyanate is 4,4′-diphenylmethane diisocyanate, or a compound of the following structure:

in which n is 0 to 6.

9. The method of claim 1 , wherein the cross-linking agent is hexamethylenediamine or polyethyleneimine.

10. The method of claim 9 , wherein the active material is a fragrance oil.

11. The method of claim 1 , wherein the polyurea capsule slurry further comprises 0.1 to 2 wt % carboxymethyl cellulose polymer.

12. The method of claim 1 , wherein the polyurea capsule slurry further comprises 0.05 to 0.2 wt % cetyl trimethyl ammonium chloride, and the capsule formation aid is a sulfonated polystyrene.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 21, 2014
From: LEI, YABIN; XU, LI; JOYCE, CAROL; POPPLEWELL, LEWIS MICHAEL
To: INTERNATIONAL FLAVORS & FRAGRANCES INC.
Reel/Frame 032006/0292 →
Continuity (4)
Continuation In Part 13163320 · Jun 17, 2011
Continuation In Part 12883337 · Sep 16, 2010
Continuation In Part 12562578 · Sep 18, 2009
Related Publication 20140017287A1 · Jan 16, 2014