Vaccine peptide combinations
The present invention relates to compositions comprising peptides for preventing or treating allergy to cats, and in particular to optimal combinations of peptides.
1. A pharmaceutical formulation comprising a pharmaceutically acceptable carrier or diluent, a preservative, and, as the only therapeutic ingredients:
the polypeptide which consists of the sequence of SEQ ID NO: 1;
the polypeptide which consists of the sequence of SEQ ID NO: 2;
the polypeptide which consists of the sequence of SEQ ID NO: 3;
the polypeptide which consists of the sequence of SEQ ID NO: 4;
the polypeptide which consists of the sequence of SEQ ID NO: 5;
the polypeptide which consists of the sequence of SEQ ID NO: 6; and
the polypeptide which consists of the sequence of SEQ ID NO: 7,
wherein each said polypeptide is present in an amount of 100 ng to 2 mg.
2. The formulation according to claim 1 , which comprises no further peptides.
3. The formulation according to claim 1 wherein each polypeptide as defined in claim 1 has a concentration in the range of 0.03 to 200 nmol/ml, 0.3 to 200 nmol/ml or 10 to 50 nmol/ml.
4. The formulation according to claim 1 , which is provided as an injectable solution, suspension or emulsion.
5. The formulation according to claim 1 , which is formulated for administration parenterally, subcutaneously, intradermally or transdermally.
6. The formulation according to claim 1 , which is provided in dry form for reconstitution.