Probiotics in a pre- and/or post-surgical environment
View Patent ↗The present invention relates generally to the field of nutrition, more particularly to the use of probiotics in nutrition. In particular the present invention relates to the use of a probiotic or of a mixture of probiotics in the manufacture of a nutritional composition or a medicament to act the colon in a pre- or post surgical environment.
1. A method comprising administering a composition comprising a probiotic to an adult patient scheduled to undergo surgery, the probiotic acts on the colon of the adult patient and is selected from the group consisting of Lactobacillus johnsonii La1 (CNCM I-1225), Bifidobacterium longum CNCM I-2170, Bifidobacterium lactis Bb12 (DSM20215), Lactobacillus paracasei CNCM I-2116, Lactobacillus paracasei CNCM I-1292, Streptococcus faecium SF 68, and combinations thereof.
2. The method of claim 1 wherein the composition is administered within three weeks of the surgery.
3. The method of claim 1 wherein the probiotic colonizes the colon of the adult patient.
4. The method of claim 1 wherein the composition modulates the immune system of the adult patient or stimulates production of mucosal secretory antibodies in the adult patient.
5. The method of claim 1 wherein the probiotic is selected from the group consisting of Bifidobacterium longum CNCM I-2170, Bifidobacterium lactis Bb12 and combinations thereof.
6. The method of claim 1 wherein the probiotic is selected from the group consisting of Lactobacillus paracasei CNCM I-2116, Lactobacillus paracasei CNCM I-1292, and combinations thereof.
7. The method of claim 1 wherein the probiotic comprises Lactobacillus johnsonii La1 (CNCM I-1225).
8. The method of claim 1 wherein the composition comprises a component selected from the group consisting of non-viable probiotic bacteria, probiotic-derived material and a combination thereof.
9. A method comprising administering a composition comprising a probiotic to an adult patient after surgery, the probiotic acts on the colon of the adult patient and is selected from the group consisting of Lactobacillus johnsonii La1 (CNCM I-1225), Bifidobacterium longum CNCM I-2170, Bifidobacterium lactis Bb12 (DSM20215), Lactobacillus paracasei CNCM I-2116, Lactobacillus paracasei CNCM I-1292, Streptococcus faecium SF 68, and combinations thereof.
10. The method of claim 9 wherein the composition is administered for a time period that comprises the day immediately after the surgery.
11. The method of claim 9 wherein the probiotic colonizes the colon of the adult patient.
12. The method of claim 9 wherein the adult patient has non-infectious diarrhea.
13. The method of claim 9 wherein the adult patient has infectious or toxigenic diarrhea.
14. The method of claim 9 wherein the adult patient has a nosocomial gastrointestinal infection.
15. The method of claim 9 wherein the composition modulates an inflammatory response during a healing process of the adult patient.
16. The method of claim 9 wherein the composition modulates the immune system of the adult patient or stimulates production of mucosal secretory antibodies in the adult patient.
17. The method of claim 9 wherein the probiotic is selected from the group consisting of Bifidobacterium longum CNCM I-2170, Bifidobacterium lactis Bb12 and combinations thereof.
18. The method of claim 9 wherein the probiotic is selected from the group consisting of Lactobacillus paracasei CNCM I-2116, Lactobacillus paracasei CNCM I-1292, and combinations thereof.
19. The method of claim 9 wherein the probiotic comprises Lactobacillus johnsonii La1 (CNCM I-1225).
20. The method of claim 9 wherein the composition comprises a component selected from the group consisting of non-viable probiotic bacteria, probiotic-derived material and a combination thereof.