Supplemention of maternal diet
View Patent ↗The use of probiotic bacteria in the manufacture of a composition for administration to a woman in at least the third trimester of pregnancy for prevention of gestational diabetes, normalizing plasma glucose concentration and/or increasing insulin sensitivity.
1. A method for normalizing plasma glucose concentration, the method comprising administering to a woman in at least the third trimester of pregnancy a therapeutically-effective amount of a composition comprising a probiotic mixture of Lactobacillus rhamnosus CGMCC 1.3724 and Bifidobacterium lactis CNCM I-3446.
2. The method of claim 1 , wherein administration of the composition continues after delivery.
3. The method of claim 1 , wherein the composition is administered to provide the probiotic mixture in a daily dose of between 10 5 to 10 12 colony forming units.
4. The method of claim 1 , wherein the composition is administered to the woman for the second and third trimesters of pregnancy.
5. The method of claim 1 , wherein the composition is administered for the full duration of the pregnancy.
6. A method for improving insulin sensitivity, the method comprising administering to a woman in at least the third trimester of pregnancy a therapeutically-effective amount of a composition comprising a probiotic mixture of Lactobacillus rhamnosus CGMCC 1.3724 and Bifidobacterium lactis CNCM I-3446.
7. The method of claim 6 , wherein the composition is administered to provide the probiotic mixture in a daily dose of between 10 5 to 10 12 colony forming units.
8. The method of claim 6 , wherein the composition is administered to the woman for the second and third trimesters of pregnancy.
9. The method of claim 6 , wherein the composition is administered for the full duration of the pregnancy.
10. A method for reducing the risk of development of metabolic syndrome, the method comprising administering to a woman in at least the third trimester of pregnancy and for at least three months after delivery a therapeutically-effective amount of a composition comprising a probiotic mixture of Lactobacillus rhamnosus CGMCC 1.3724 and Bifidobacterium lactis CNCM I-3446.
11. The method of claim 10 , wherein the composition is administered to provide the probiotic mixture in a daily dose of between 10 5 to 10 12 colony forming units.
12. The method of claim 10 , wherein the composition is administered to the woman for the second and third trimesters of pregnancy.
13. The method of claim 10 , wherein the composition is administered for the full duration of the pregnancy.
14. A method for reducing the risk of metabolic syndrome in infant(s), the method comprising administering to a woman in at least the third trimester of pregnancy a therapeutically-effective amount of a composition comprising a probiotic mixture of Lactobacillus rhamnosus CGMCC 1.3724 and Bifidobacterium lactis CNCM I-3446.
15. The method of claim 14 wherein, the composition is administered to provide the probiotic mixture in a daily dose of between 10 5 to 10 12 colony forming units.