IP Library Granted Patent US 9,636,524
Granted Patent B2
US 9,636,524 · App. 14/190,389 · Granted May 2, 2017

Neutron source for neutron capture therapy

Inventors: Richard Harris Pantell (Portola Valley, CA); Charles Kevin Gary (Palo Alto, CA); Melvin Arthur Piestrup (Woodside, CA)
Assignee: Adelphi Technology, Inc.
A61N5/1077A61N5/10A61N2005/109A61N2005/1094
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Quick Facts
Patent No.
US 9,636,524
App. No.
14/190,389
Granted
May 2, 2017
Kind
B2
Abstract

A therapy apparatus for producing thermal neutrons at a tumor site in a patient has a plurality of fast neutron sources surrounding a moderator, a fast neutron reflecting media around the fast neutron sources, a gamma-ray and neutron shielding media surrounding the fast neutron reflecting media, and a patient chamber positioned inside the moderator. The fast neutron sources are positioned around the moderator to maximize and direct the neutron flux to said tumor site.

Claims (12)

1. A neutron-capture therapy apparatus comprising:

a cylindrical moderator structure composed primarily of a moderator material, having a length, an outside diameter, a cylindrical outer surface, an inside diameter, and a cylindrical inner surface, the inside diameter and length defining a treatment zone;

a plurality of fusion neutron generators arranged in an array surrounding the cylindrical outer surface of the cylindrical moderator structure, each fusion neutron generator comprising an ion source emitting ions toward target material positioned at the cylindrical outside surface of the cylindrical moderator structure, the ions accelerated toward the target material by a DC voltage imposed between the target material and the ion source, impingement of the ions at the target material producing fast neutrons by a fusion reaction in the target material; and

a cylindrical fast neutron reflector surrounding the cylindrical moderator structure and the fusion neutron generators;

wherein fast neutrons are emitted isotropically from the target material at a plurality of different positions around the cylindrical outer surface of the moderator structure as a result of ion bombardment, neutrons emitted in a direction toward the cylindrical fast neutron reflector are reflected back into the cylindrical moderator structure, and moderated epithermal neutrons enter the treatment zone across the entire cylindrical inner surface of the moderator structure.

2. The neutron-capture therapy apparatus of claim 1 wherein the ion sources are equally spaced apart in a circular array.

3. The neutron-capture therapy apparatus of claim 1 wherein the target material is titanium, and is provided at the cylindrical outside surface of the moderator structure as a plurality of targets, one target corresponding to each fusion neutron generator.

4. The neutron-capture therapy apparatus of claim 1 wherein the ion sources are embedded in the cylindrical fast neutron reflector.

5. The neutron-capture therapy apparatus of claim 1 wherein fast-neutron generators are embedded in the cylindrical moderator structure.

6. The neutron-capture therapy apparatus of claim 1 wherein the target material is contiguous around the cylindrical outside surface of the cylindrical moderator structure.

7. The neutron-capture therapy apparatus of claim 1 wherein the cylindrical moderator structure comprises a plurality of wedge-shaped elements, equal in number to the plurality of fast-neutron generators, and each fast-neutron generator is embedded in one wedge shaped moderator element.

8. The neutron-capture therapy apparatus of claim 7 wherein the wedge-shaped elements are adjustable in position, changing flux density at different positions in the treatment zone.

Continuity (3)
Division 13532447 · Jun 25, 2012
Provisional Application 61571406 · Jun 27, 2011
Related Publication 20140179978A1 · Jun 26, 2014