Devices and methods for weight control and weight loss
The present invention provides, compositions, devices; and methods for affecting, among other things, weight loss and/or weight control, by sequestering nutrients or other compounds such as toxins from absorption in the digestive tract. The compositions, devices, and methods employ one or more members made of a compressible, absorbent matrix material. In various embodiments, the matrix material is suitable for routine use. The compressible absorbent matrix material has a size, shape and/or geometry configured for efficient packing into a small space, and/or configured to absorb and substantially retain digested material in the stomach. The devices and compositions may further comprise one or more hydrogel(s), soluble or insoluble fibers, waxes and/or gums to provide the desired mechanical properties and/or absorptive or shielding properties.
1. A device for preventing absorption of nutrients or other compounds in the stomach, the device comprising:
one or more member of a compressible absorbent matrix material having a configuration that is packed into a compressed delivery vehicle that is less than 50% of an expanded size of the delivery vehicle, wherein the absorbent matrix material forms a sponge architecture, including a plurality of cells defined by cell walls, wherein the absorbent matrix material, once released in the stomach, absorbs nearby nutrients or compounds thereby preventing the stomach from absorbing the same nutrients or compounds, and wherein one or more sealing compounds are contained in the cell walls; and
a delivery vehicle that encapsulates the compressible absorbent matrix material, wherein the delivery vehicle is ingested by a user, and wherein the ingestion triggers a release of the compressible absorbent matrix into the stomach of a user.
2. The device of claim 1 , wherein the compounds absorbed by the absorbent matrix material includes toxins.
3. The device of claim 1 , wherein the compounds absorbed by the absorbent matrix material includes alcohol.
4. The device of claim 1 , wherein the delivery vehicle is made of material that is resistant to fluids at normal pH but dissolves in an acidic environment.
5. The device of claim 4 , wherein the acidic environment is the stomach of the user.
6. The device of claim 4 , wherein the material for the delivery vehicle is polylactic acid.
7. The device of claim 1 , wherein the compressible absorbent matrix material is comprised of a mixture producing a less permeable feature that inhibits fluids from entering or exiting the absorbent matrix material after an initial absorption of nutrients or other compounds.
8. The device of claim 1 , wherein the absorbent matrix material is made of materials safe for human ingestion.
9. The device of claim 1 , wherein the compressible absorbent matrix material partially or totally disintegrate in the lower GI tract of the user corresponding to a section after the upper GI tract where most absorption occurs.
10. A method for preventing absorption of nutrients or other compounds in the stomach, the method comprising:
encapsulating, via a compressed delivery vehicle, one or more members of a compressible absorbent matrix material having a configuration that is packed into the compressed delivery vehicle that is less than 50% of an expanded size of the compressed delivery vehicle, wherein the absorbent matrix material forms a sponge architecture, including a plurality of cells defined by cell walls, and wherein one or more sealing compounds are contained in the cell walls; and
releasing the one or more members of the compressible absorbent matrix material in a stomach, wherein the compressible absorbent matrix material absorb nearby nutrients or compounds thereby preventing the stomach from absorbing the same nutrients or compounds.
11. The method of claim 10 , wherein absorbing nearby nutrients or compounds includes absorbing toxins.
12. The method of claim 10 , wherein absorbing nearby nutrients or compounds includes absorbing alcohol.
13. The method of claim 10 , wherein releasing the one or more members of the compressible absorbent matrix material in a stomach includes triggering the release, the trigger based on a material selected for the delivery vehicle.
14. The method of claim 13 , wherein the material selected for the delivery vehicle is resistant to fluids at normal pH but dissolves in an acidic environment.
15. The method of claim 14 , wherein the acidic environment is a stomach.
16. The method of claim 14 , wherein the material selected for the delivery vehicle is polylactic acid.
17. The method of claim 10 , wherein the compressible absorbent matrix material is comprised of a mixture producing a less permeable feature that inhibits fluids from entering or exiting the absorbent matrix after an initial absorption of nutrients of other compounds.
18. The method of claim 10 , wherein the absorbent matrix material is made of materials safe for human ingestion.
19. The method of claim 10 , wherein the compressible absorbent matrix material partially or totally disintegrate in the lower GI tract of the user corresponding to a section after the upper GI tract where most absorption occurs.