IP Library Granted Patent US 10,758,988
Granted Patent B2
US 10,758,988 · App. 14/489,901 · Granted Sep 1, 2020

Method for conducting maintenance on a chromatography column

Inventors: John Davis (Uppsala, SE); Stefan Kjell Eriksson (Uppsala, SE)
Assignee: Cytiva Sweden AB
B23C3/18B01D15/10G01N30/56
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Quick Facts
Patent No.
US 10,758,988
App. No.
14/489,901
Granted
Sep 1, 2020
Kind
B2
Abstract

The present invention relates to methods for conducting maintenance on chromatography columns used in industrial-scale chromatography. In particular, the invention is concerned with safer methods for performing maintenance on such columns, such as cleaning and replacing bed supports, distributors, nozzles, O-rings and other column components, by the use of a handling device to support, lift, carry and manipulate such column components.

Claims (22)

1. A handling device for providing independent support during chromatography column maintenance to detached column components including a bed support and a distributor of the chromatography column,

wherein the handling device is independent of a Chromatography column support and drive system of the chromatography column and the chromatography column support and drive system comprises:

at least one vertical pillar positioned around the chromatography column; and

a drive system for lifting components of the chromatography column up and down, independent of the handling device;

the handling device comprising:

a frame with wheels and a vertical handling device pillar supported by the frame,

at least one extendable arm attached to the vertical handling device pillar, projecting horizontally from said vertical handling device pillar, configured to bear the weight of the column components, and extendable to the diameter of the bed support and the distributor, and

attachment Means on the at least one extendable arm for securing the column component thereto,

wherein said at least one extendable arm is movable vertically along the axis of the vertical handling device pillar and capable of reaching in between the vertical pillars of the column.

2. The handling device of claim 1 , wherein the at least one extendable arm is attached to the vertical handling device, pillar through a joint and said at least one extendable arm can rotate or pivot around the joint.

3. The handling device of claim 1 , comprising at least two extendable arms; and further comprising a conical raised element at the intersection of the at least two extendable arms for centralizing the column components.

4. The handling device of claim 1 , wherein the attachment means comprises a fixture for receipt of fixing means in the column component.

5. The handling device of claim 1 , wherein the at least one extendable arm additionally comprises a pad for resting the column component thereon.

6. The handling device of claim 1 , wherein the at least one extendable arm is movable vertically along the axis of the vertical handling device pillar through a jack.

7. The handling device of claim 1 , wherein the at least one extendable arm is movable vertically along the axis of the vertical handling device pillar through mechanical means powered by electrical, pneumatic or hydraulic means.

8. Tire handling device of claim 1 , further comprising a handle to facilitate steering.

9. The handling device of claim 1 , wherein the wheels rotate independently of each other.

10. The handling device of claim 1 , wherein the wheels lock independently of each other.

11. The handling device of claim 1 , wherein the wheels are levelable independently of each other.

12. The handling device of claim 1 , wherein tyre wheels are powered by electricity.

13. The handling device of claim 1 , wherein the at least one extendable arm is removable and replaceable with a different arm to suit different column components.

14. The handling device of claim 1 , wherein the attachment means comprises a fixture in the form of holes, clips, clamps, or fasteners at an extremity of the at least one extendable arm for receipt of a fixing means of the column component.

Assignments (2)
CHANGE OF NAME Recorded Jul 16, 2020
From: GE HEALTHCARE BIO-SCIENCES AB
To: CYTIVA SWEDEN AB
Reel/Frame 054058/0384 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 15, 2020
From: DAVIS, JOHN; ERIKSSON, STEFAN KJELL
To: GE HEALTHCARE BIO-SCIENCES AB
Reel/Frame 053211/0133 →
Continuity (4)
Division 12838809 · Jul 19, 2010
Division 11834864 · Aug 7, 2007
Continuation In Part 11763477 · Jun 15, 2007
Related Publication 20150001775A1 · Jan 1, 2015