Nutritional composition containing oligosaccharide mixture
View Patent ↗A nutritional composition for administration to an infant which composition comprises, on a dry matter basis, from 2.5 to 15.0 wt % of an oligosaccharide mixture consisting of N-acetylated oligosaccharide(s), galacto-oligosaccharide(s) and sialylated oligosaccharide(s) with the proviso that the composition comprises at least 0.02 wt % of an N-acetylated oligosaccharide, at least 2.0 wt % of a galacto-oligosaccharide and at least 0.04 wt % of a sialylated oligosaccharide and that the N-acetylated oligosaccharide(s) comprise 0.5 to 4.0% of the oligosaccharide mixture, the galacto-oligosaccharide(s) comprise 92.0 to 98.5% of the oligosaccharide mixture and the sialylated oligosaccharide(s) comprise 1.0 to 4.0% of the oligosaccharide mixture. The composition is useful for administration to an infant in the first six months of life to reduce the risk of obesity later in life.
1. A method for reducing the risk of obesity later in life to an infant, the method comprising administering a nutritional composition comprising therapeutically effective amounts of an N-acetylated oligosaccharide, a galacto-oligosaccharide and a sialylated oligosaccharide to an infant in the first six months of life.
2. The method of claim 1 , wherein the N-acetylated oligosaccharide is selected from the group consisting of GalNAcα1,3Galβ1,4Glc; Galβ1,6GalNAcα1,3Galβ1,4Glc and a mixture thereof.
3. The method of claim 1 , wherein the galacto-oligosaccharide is selected from the group consisting of Galβ1,6Gal; Galβ1,6Galβ1,4Glc; Galβ1,6Galβ1,6Glc; Galβ1,3Galβ1,3Glc; Galβ1,3Galβ1,4Glc; Galβ1,6Galβ1,6Galβ1,4Glc; Galβ1,6Galβ1,3Galβ1,4Glc; Galβ1,3Galβ1,6Galβ1,4Glc; Galβ1,3Galβ1,3Galβ1,4Glc; Galβ1,4Galβ1,4Glc; and Galβ1,4Galβ1,4Galβ1,4Glc and mixtures thereof.
4. The method of claim 1 , wherein the sialylated oligosaccharide is selected from the group consisting of NeuAcα2,3Galβ1,4Glc, NeuAcα2,6Galβ1,4Glc and a mixture thereof.