IP Library Granted Patent US 9,089,602
Granted Patent B2
US 9,089,602 · App. 14/550,691 · Granted Jul 28, 2015

Compositions and methods for the prevention and treatment of cardiovascular diseases

Inventors: Henk Van Wyk (Denver, CO); Mariette Van Wyk (Denver, CO); Trace Krebs (Sarasota, FL); Peter Lange (Denver, CO); Brian Denomme (Northville, MI); Michael A. Volk (Broomfield, CO)
Assignee: REVEN PHARMACEUTICALS, INC.
A61K41/0047A61K31/167A61K31/375A61K31/4415A61K31/455A61K31/51A61K31/675A61K31/714A61K33/06
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Quick Facts
Patent No.
US 9,089,602
App. No.
14/550,691
Granted
Jul 28, 2015
Kind
B2
Abstract

Compositions comprising electro-activated aqueous solutions and methods for the prevention and treatment of dysfunctional cardiovascular conditions are provided.

Claims (10)

1. A stable therapeutic composition comprising an electro-activated solution, wherein the electro-activated solution has an oxidation-reduction potential (ORP) in the range between −500 mV and −900 mV for a period of at least 12 months and a pH in the range between 3.2 and 4.5, and the composition comprises:

Ascorbic acid 83.6-95.5 g/L;

Magnesium Sulphate hexahydrate 57.1-64.7 g/L;

2-diethylaminoaceto,xylidide 31.5-37.5 g/L;

Niacinamide 9.4-10.7 g/L;

Pyridoxin HCL 9.4-10.7 g/L;

Riboflavin-5-phosphate sodium 0.18-0.2 g/L;

Thiamin HCL 5.75-6.5 g/L;

Cyanocobalamin crystalline 0.17-0.2 g/L; and

Electrochemically activated water+.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 23, 2015
From: VAN WYK, HENK; VAN WYK, MARIETTE; KREBS, TRACY L; LANGE, PETER B; DENOMME, BRIAN; VOLK, MICHAEL A
To: NOVENTIS, INC.
Reel/Frame 035953/0785 →
CHANGE OF ASSIGNEE'S ADDRESS Recorded Jun 23, 2015
From: REVEN PHARMACEUTICALS, INC.
To: REVEN PHARMACEUTICALS, INC.
Reel/Frame 036007/0477 →
CHANGE OF NAME Recorded Jun 23, 2015
From: NOVENTIS, INC.
To: REVEN PHARMACEUTICALS, INC.
Reel/Frame 036010/0021 →
Continuity (3)
Division 13055691
Provisional Application 61129883 · Jul 25, 2008
Related Publication 20150140129A1 · May 21, 2015