IP Library Granted Patent US 9,579,442
Granted Patent B2
US 9,579,442 · App. 14/589,301 · Granted Feb 28, 2017

Array of hollow fibers and a system and method of manufacturing same

Inventors: Anna M. Galea (Stow, MA); Kristen LeRoy (Somerville, MA); Nicholas Vitale (Albany, NY)
Assignee: Lung Biotechnology PBC
A61M1/1698B01D19/0073B01D53/22B01D53/228B01D63/02B01D63/021B01D63/022B01D63/04B01D67/00B01D69/08B29C65/48A61M2202/0208A61M2202/0225B01D2053/224B01D2325/20
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Quick Facts
Patent No.
US 9,579,442
App. No.
14/589,301
Granted
Feb 28, 2017
Kind
B2
Abstract

An array of hollow fibers including a plurality of hollow fibers of a predetermined diameter configured to receive a gas having oxygen therein and transfer the oxygen to a fluid and/or transfer carbon dioxide in the fluid to a gas. The array is configured in a predetermined pattern having a predetermined packing density that is a fraction of a total cross-sectional area of the array occupied by the hollow fibers.

Claims (14)

1. An array of hollow fibers comprising:

a plurality of hollow fibers of a predetermined diameter configured to receive a gas having oxygen therein and transfer the oxygen to a fluid and/or transfer carbon dioxide from the fluid to the gas; and

a plurality of headers having a plurality of recesses configured to receive the plurality of hollow fibers,

wherein the plurality of headers is configured to align the plurality of hollow fibers in a predetermined regular pattern having a predetermined packing density that is a fraction of a total cross-sectional area of the array occupied by the hollow fibers, in which array the hollow fibers are aligned such that spacing between the hollow fibers is relatively constant along the length of the array.

2. The array of claim 1 in which the array is configured such that the distance between the hollow fibers is less than or substantially equal to the predetermined diameter.

3. The array of claim 1 in which the fraction is in the range of 0.20 to about 0.90.

4. The array of claim 1 in which the plurality of hollow fibers are configured in a hexagonal arrangement.

5. The array of claim 4 in which the plurality of hollow fibers is configured to be hexagonally closely packed.

6. The array of claim 1 in which the plurality of headers comprises

a first end-header having a plurality of recesses on one side configured to receive a first layer of the plurality of hollow fibers;

a second end-header having a plurality of recesses on one side configured to receive a second layer of the plurality of hollow fibers; and

a plurality of mid-headers having a plurality of recesses on both sides configured to receive the plurality of hollow fibers,

wherein a first of the plurality of mid-headers is configured to receive the first layer of the plurality of hollow fibers such that the first layer of the plurality of hollow fibers is sandwiched between the first end-header and the first of the plurality of mid-headers, and

wherein a second of the plurality of mid-headers is configured to receive the second layer of the plurality of hollow fibers such that the second layer of the plurality of hollow fibers is sandwiched between the second end-header and the second of the plurality of mid-headers.

Assignments (5)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 31, 2021
From: LUNG BIOTECHNOLOGY PBC
To: VIVONICS, INC.
Reel/Frame 055782/0790 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 26, 2016
From: GALEA, ANNA M.; LEROY, KRISTEN; VITALE, NICHOLAS
To: INFOSCITEX CORPORATION
Reel/Frame 039854/0465 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 26, 2016
From: INFOSCITEX CORPORATION
To: VIVONICS, INC.
Reel/Frame 039854/0697 →
CONFIRMATORY LICENSE Recorded Sep 26, 2016
From: VIVONICS, INC.
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 039854/0928 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 26, 2016
From: VIVONICS, INC.
To: LUNG BIOTECHNOLOGY PBC
Reel/Frame 039855/0236 →
Continuity (2)
Continuation 13506306 · Apr 10, 2012
Related Publication 20150202357A1 · Jul 23, 2015