α-keto peracids and methods for producing and using the same
The present invention provides α-keto peracids and methods for producing and using the same. In particular, α-keto peracids are useful as antimicrobial agents.
1. A method for reducing the amount of microbe on an irritated, injured, or acne-affected skin comprising contacting the skin with an antimicrobial solution comprising an effective amount of a peroxy α-ketocarboxylic acid.
2. The method of claim 1 , wherein the peroxy α-ketocarboxylic acid is selected from the group consisting of peroxy pyruvic acid, peroxy α-ketobutyric acid, peroxy α-ketovaleric acid, or combination thereof.
3. The method of claim 1 , wherein the antimicrobial solution is a personal care product selected from the group consisting of hand soaps, hand sanitizers, skin gels/wipes, body washes, mouth washes, toothpastes, shower gels, shampoos, body lotions, deodorants, nasal sprays, foot care, vaginal care and/or wash, and combination thereof.
4. The method of claim 3 , wherein the personal care product is a hand sanitizer.
5. The method of claim 3 , wherein the personal care product is in the form of a wipe.
6. The method of claim 3 , wherein the personal care product is in the form of a liquid or a gel.
7. The method of claim 3 , wherein the personal care product is in the form of a spray.
8. The method of claim 1 , wherein the antimicrobial solution is effective against C. Difficile.
9. The method of claim 1 , wherein the antimicrobial solution is effective against gram-positive bacteria, gram-negative bacteria, bacterial spores, viruses, fungi, prions and combination thereof.
10. The method of claim 1 , wherein the amount of the peroxy α-ketocarboxylic acid present in the antimicrobial solution is about 500 ppm or less.
11. The method of claim 1 , wherein the antimicrobial solution further comprises an antimicrobial agent, antifungal agent, or an anti-inflammatory agent.
12. The method of claim 1 , wherein the antimicrobial solution further comprises an organic acid.
13. The method of claim 1 , wherein the antimicrobial solution further comprises hydrogen peroxide.
14. The method of claim 1 , wherein the antimicrobial solution further comprises an alcohol.
15. The method of claim 1 , wherein the antimicrobial solution further comprises an ether.
16. The method of claim 1 , wherein the antimicrobial solution further comprises a surfactant.