IP Library Granted Patent US 9,353,098
Granted Patent B2
US 9,353,098 · App. 14/753,141 · Granted May 31, 2016

Polymorphs and salts

Inventors: Julie Nicole Hamblin (Stevenage, GB); Paul Spencer Jones (Stevenage, GB); Suzanne Elaine Keeling (Stevenage, GB); Joelle Le (Stevenage, GB); Charlotte Jane Mitchell (Stevenage, GB); Nigel James Parr (Stevenage, GB); Robert David Willacy (Stevenage, GB)
Assignee: Glaxo Group Limited
C07D413/14
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Quick Facts
Patent No.
US 9,353,098
App. No.
14/753,141
Granted
May 31, 2016
Kind
B2
Abstract

The present invention is directed to novel polymorphs and salts of a compound which is an inhibitor of kinase activity.

Claims (3)

1. A polymorph (Form IV) of N-[5-[4-(5-{[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl}-1,3-oxazol-2-yl)-1H-indazol-6-yl]-2-(methyloxy)-3-pyridinyl]methanesulfonamide characterised in that it provides an XRPD pattern comprising a peak (°2θ) at about 5.8.

2. A polymorph according to claim 1 characterised in that it provides an XRPD pattern comprising peaks substantially as set out in Table 3.

3. A polymorph according to claim 1 characterised in that it provides an XRPD pattern substantially in accordance with FIG. 3 .

Assignments (2)
CHANGE OF ADDRESS Recorded Apr 16, 2025
From: GLAXO GROUP LIMITED
To: GLAXO GROUP LIMITED
Reel/Frame 071044/0904 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 29, 2015
From: HAMBLIN, JULIE NICOLE; JONES, PAUL SPENCER; KEELING, SUZANNE ELAINE; LE, JOELLE; MITCHELL, CHARLOTTE JANE; PARR, NIGEL JAMES; WILLACY, ROBERT JAMES
To: GLAXO GROUP LIMITED
Reel/Frame 035957/0294 →
Continuity (4)
Continuation 14251778 · Apr 14, 2014
Continuation 13821585
Provisional Application 61380748 · Sep 8, 2010
Related Publication 20150299177A1 · Oct 22, 2015