Compositions for use in stimulating bone growth
View Patent ↗The present invention relates to use of a composition for maintenance of bone and/or cartilage health or prevention, alleviation and/or treatment of bone and/or cartilage disorders.
1. A method for potentiating the effects of oleuropein on bone formation and/or cartilage anabolism, the method comprising administering a composition comprising 800 to 1200 IU of Vitamin D and further comprising the oleuropein to an individual in need of same, wherein the composition is administered to the individual at least once per day, for a time period of at least 2 months.
2. The method according to claim 1 , wherein the composition comprises 850 to 1000 IU of the Vitamin D.
3. The method according to claim 1 , wherein the composition comprises 900 to 950 IU of the Vitamin D.
4. The method according to claim 1 , wherein the composition comprises from 0.01 mg to 1 g of the oleuropein.
5. The method according to claim 1 , wherein the composition comprises one or more further bioactive molecules.
6. The method according to claim 5 , wherein the one or more further bioactive molecules comprise a mineral comprising calcium and/or magnesium.
7. The method according to claim 1 , wherein the individual is a member of an ageing population.
8. The method according to claim 1 , wherein the individual has a disorder linked to an imbalance in the relationship between bone formation and/or cartilage anabolism and bone resorption, and the composition comprises the oleuropein in an amount effective to potentiate stimulation of cartilage anabolism in the individual.
9. The method according to claim 1 , wherein the composition comprises the oleuropein in an amount effective to maintain and/or improve mobility in the individual.
10. The method according to claim 8 , wherein the disorder is osteoporosis.
11. The method according to claim 1 , wherein the composition is a nutritional composition.
12. A method of treatment and/or alleviation of a disorder linked to an imbalance in bone and/or cartilage metabolism, the method comprising administering a composition comprising an effective amount of 800 to 1200 IU of Vitamin D in combination with oleuropein to an individual having the disorder, wherein the composition is administered at least once per day, for a time period of at least 2 months.
13. The method according to claim 12 , wherein the composition comprises one or more further bioactive molecules.
14. The method according to claim 13 , wherein the one or more further bioactive molecules comprise a mineral comprising calcium and/or magnesium.
15. The method according to claim 12 , wherein the composition comprises 0.01 mg to 1 g of the oleuropein.
16. The method according to claim 12 , wherein the composition comprises the oleuropein in an amount effective to potentiate stimulation of bone formation and/or cartilage anabolism in the individual.
17. The method according to claim 12 , wherein the composition comprises the oleuropein in an amount effective to maintain and/or improve mobility in the individual.
18. The method according to claim 12 , wherein the disorder is osteoporosis.
19. The method according to claim 12 , wherein the composition is a nutritional composition.