Composition for preventing or treating climacteric symptoms comprising soybean extract comprising coumestrol as an active ingredient
The present invention relates to a composition for, inter alia, preventing or treating a climacteric disease, or preventing or improving a climacteric skin symptom comprising a soybean extract comprising coumestrol as an active ingredient, and more specifically relates to a composition for, inter alia, preventing or treating a climacteric disease, or preventing or improving a climacteric skin symptom comprising a germinated and fermented soybean extract comprising coumestrol as an active ingredient.
1. A method for preventing or treating a climacteric disease, wherein the method comprises administering an effective amount of a germinated and fermented bean extract comprising coumestrol to a subject in need thereof, wherein the method is for preventing or treating a climacteric disease,
wherein the fermented bean extract is a fermented product by Aspergillus oryzae of the germinated bean,
wherein the climacteric disease is osteoporosis.
2. The method according to claim 1 , wherein the germination is performed by germinating 1-50 vol % of the bean in a reactor comprising 20-80 vol % of a medium based on the total volume of the reactor.
3. The method according to claim 1 , wherein the germination is performed at 20-35 ° C. under a dark condition for 2-10 days.
4. The method according to claim 1 , wherein the germinated and fermented bean extract comprising coumestrol is administered in form of a composition comprising 0.0001-10 wt % of the germinated and fermented bean extract comprising coumestrol based on the total weight of the composition.
5. The method according to claim 1 , wherein the germinated and fermented bean extract comprising coumestrol is administered in the form of a pharmaceutical composition.
6. The method according to claim 1 , wherein the germinated and fermented bean extract comprising coumestrol is administered in the form of a health food composition.
7. The method according to claim 1 , wherein the germinated and fermented bean extract comprising coumestrol is administered in the form of a cosmetic composition.