Method for treating a swallowing disorder
This invention relates to a method for treating a swallowing disorder in a patient suffering from aspiration before, during and/or after the swallowing reflex, and to a bolus for use in the treatment of a swallowing disorder in such a patient.
1. A method for mitigating difficulty in and/or impairment of swallowing in a patient suffering from aspiration, the method comprising:
(1) Classifying the patient into a patient group selected from the group consisting of:
(a) Aspiration before the swallowing reflex,
(b) Aspiration during the swallowing reflex,
(c) Aspiration after the swallowing reflex,
(d) Aspiration before and during the swallowing reflex,
(e) Aspiration before and after the swallowing reflex, and
(f) Aspiration during and after the swallowing reflex;
(2) Supplying (i) a first liquid having a shear viscosity from 5 to 45 mPas when measured at a shear rate of 50 s−1 and a relaxation time, determined by a Capillary Breakup Extensional Rheometry (CaBER) experiment, of more than 10 ms (milliseconds) at a temperature of 20° C. and (ii) a second liquid having a shear viscosity more than 50 mPas when measured at a shear rate of 50 s−1 and a relaxation time, determined by a CaBER experiment, of more than 10 ms (milliseconds) at a temperature of 20° C.;
(3) Selecting a bolus based on the selected patient group according to step (1) from the first liquid and the second liquid; and
(4) Administering the bolus to the patient, wherein the bolus comprises at least one food grade biopolymer selected from the group consisting of okra gum, kiwi fruit mucilage, cactus mucilage, and combinations thereof.
2. The method according to claim 1 , wherein the bolus comprises the at least one food grade biopolymer in a concentration from at least 0.01 wt % to 25 wt %.
3. The method according to claim 1 , wherein the bolus is in an administrable form selected from the group consisting of a nutritional supplement, a full meal, a nutritionally complete formula, a pharmaceutical formulation, functional food, a beverage product, and combinations thereof.
4. The method according to claim 1 , wherein the second liquid has a shear viscosity from 55 to 350 mPas when measured at a shear rate of 50 s−1.
5. The method according to claim 1 wherein the bolus comprises the at least one food grade biopolymer in a concentration from 1 wt % to 10 wt %.
6. The method according to claim 1 , wherein the patient is classified into one of the patient groups (a), (c), (d), (e) and (f); and the bolus administered to the patient is the first liquid.
7. The method according to claim 1 , wherein the patient is classified into one of the patient groups (c), (d) and (f); and the bolus administered to the patient is the second liquid.