Treatment or prevention of autism disorders using menthol, linalool and/or icilin
View Patent ↗Compositions for treatment or prevention of autism disorders are provided, and the compositions contain a therapeutically effective amount of a compound selected from the group consisting of Menthol, Linalool, Icilin and combinations thereof. Methods for treatment or prevention of autism disorders are also provided, and the methods include administering such compositions.
1. A method for treating an autism disorder comprising administering to an individual having the autism disorder a composition comprising Menthol, and the composition is administered daily in an amount that provides a daily dose of the Menthol from 10.0 mg/kg of body weight of the individual to 100.0 mg/kg of body weight of the individual.
2. The method of claim 1 wherein the autism disorder is selected from the group consisting of classic autism, Asperger's syndrome, childhood disintegrative disorder, Rett syndrome, pervasive developmental disorders-not otherwise specified, fragile X syndrome, and combinations thereof.
3. The method of claim 1 wherein the composition is selected from the group consisting of a medicament, a food product and a supplement to a food product.
4. The method of claim 1 wherein the composition is administered daily for at least one year.
5. The method of claim 1 wherein the individual is an infant.
6. The method of claim 1 wherein the individual is a young child.
7. The method of claim 1 wherein the composition is administered for at least two years.
8. The method of claim 1 wherein the composition further comprises protective hydrocolloids.
9. The method of claim 1 wherein the composition is a food product.
10. The method of claim 9 wherein the food product comprises a component selected from the group consisting of protein, carbohydrate, fat and combinations thereof.
11. The method of claim 1 wherein the composition does not contain glutamate antagonists.
12. The method of claim 1 wherein the composition is a food product consisting of the Menthol and optionally one or more components selected from the group consisting of protein, carbohydrate, fat, an acidulant, a thickener, a buffer, a pH adjustment agent, a chelating agent, a colorant, an emulsifier, an excipient, a flavor agent, a mineral, an osmotic agent, a pharmaceutically acceptable carrier, a preservative, a stabilizer, a sugar, a sweetener, a texturizer and a vitamin.
13. The method of claim 1 wherein the composition is a food supplement consisting of the Menthol and optionally one or more components selected from the group consisting of a gum, a protein, a modified starch, a binder, a film forming agent, an encapsulating agent, a wall or shell material, a matrix compound, a coating, an emulsifier, a surface active agent, an oil, a fat, a wax, lecithin, an adsorbent, a carrier, a filler, a co-compound, a dispersing agent, a wetting agent, a solvents, a flowing agent, a taste masking agent, a weighting agent, a jellifying agent, and a gel forming agent.