IP Library › Granted Patent US 9,580,467
Granted Patent B2
US 9,580,467 · App. 14/939,547 · Granted Feb 28, 2017

Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof

Inventors: Heng Cheng (Foster City, CA); Sanjeev Gangwar (Foster City, CA); Qiang Cong (Sunnyvale, CA)
Assignee: E. R. SQUIBB & SONS, L.L.C.
C07K7/06A61K38/06A61K47/48415A61K47/48484C07C229/14C07C229/16C07K5/021C07K5/06139C07K5/10C07K16/18
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Quick Facts
Patent No.
US 9,580,467
App. No.
14/939,547
Granted
Feb 28, 2017
Kind
B2
Abstract

Antiproliferative compounds having a structure represented by formula (II), where n, R 1 , R 2 , R 3 , R 4 , and R 5 are as defined herein, can be used to treat tumors, optionally when conjugated to a ligand such as an antibody:

Claims (1)

1. A compound having a structure according to formula (VI-t)

Assignments (1)
MERGER Recorded Jan 17, 2017
From: MEDAREX, L.L.C.
To: E. R. SQUIBB & SONS, L.L.C.
Reel/Frame 040986/0472 →
Continuity (6)
Continuation 14324480 · Jul 7, 2014
Continuation 13752619 · Jan 29, 2013
Division 12846493 · Jul 29, 2010
Provisional Application 61232883 · Aug 11, 2009
Provisional Application 61230932 · Aug 3, 2009
Related Publication 20160060294A1 · Mar 3, 2016