Compositions for preventing or treating allergies in infants from or fed by non secretor mothers by providing fucosylated-oligosaccharides in particular among infants at risk or born by C-section
The present invention relates to a composition comprising at least one fucosylated oligosaccharide, for use in preventing allergies and/or treating allergies and/or reducing the occurrence or the risk of allergies in an infant or a young child born from a mother deficient in at least one fucosylated oligosaccharide(s) or fed with a mother's milk deficient in at least one fucosylated oligosaccharide(s). The use of said composition in infant formula, milk fortifier or children's food is foreseen.
1. A method for treating allergies and/or reducing the occurrence or a risk of allergies in an infant or young child born by caesarean section (C-section) and fed with a mother's milk having an amount of 2′-fucosylated oligosaccharides that is less than 3,000 mg/L, the method comprising administering to the infant or young child a composition comprising an effective amount of 2′-fucosyllactose (2FL) that is the only human milk oligosaccharide in the composition.
2. The method according to claim 1 wherein the infant or young child has at least one sibling and/or has a family history of allergy.
3. The method according to claim 1 wherein the effective amount of the 2FL is effective to treat and/or reduce a risk of allergies that start to occur at or before the age of 2 and/or comprises eczema or atopic diseases.
4. The method according to claim 1 wherein the composition comprises 0.1 g to 10 g of the 2FL per 100 g of the composition on a dry weight basis.
5. The method according to claim 1 wherein the composition comprises 1 g to 2 g of the 2FL per 100 g of the composition on a dry weight basis.
6. The method according to claim 1 , wherein the composition further comprises at least one probiotic in an amount of from 10 3 to 10 12 cfu/g of the composition (dry weight).
7. The method according to claim 1 , wherein the composition is selected from the group consisting of a nutritional composition, a preparation and a food product.
8. The method according to claim 1 , wherein the composition is selected from the group consisting of an infant formula, a starter infant formula, a follow-on infant formula, a baby food, an infant cereal composition, a fortifier, a human milk fortifier and a supplement.
9. The method according to claim 1 , wherein the infant is born preterm.
10. The method according to claim 1 , wherein the composition comprises hydrolyzed proteins as sole source or primary source of proteins.
11. The method according to claim 1 , wherein the infant or young child is secretor.