Modified saponins for the treatment of fungal infections

1. A method of treating a fungal infection in a subject, the method comprising administering to the subject a therapeutically effective amount of a compound of Formula III:

or a pharmaceutically acceptable salt thereof, wherein:

R 1 is H or C(O)R B ;

R 2 is C 1-6 alkyl or aryl; and

R B is C 2-6 alkenyl.

2. The method of claim 1 , wherein the compound is:

or a pharmaceutically acceptable salt thereof.

3. The method of claim 1 , wherein the compound is:

or a pharmaceutically acceptable salt thereof.

4. The method of claim 1 , wherein the fungal infection is infection with a Candida species fungus.

5. The method of claim 4 , wherein the Candida species is C. albicans.