IP Library Granted Patent US 10,213,626
Granted Patent B2
US 10,213,626 · App. 15/152,479 · Granted Feb 26, 2019

Treatment delivery control system and method of operation thereof

Inventors: Vladimir Balakin (Protvino, RU); Stephen L. Spotts (Argyle, TX)
A61N5/1077A61B6/03A61N5/1044A61N5/1067A61N5/1082G21K1/087G21K1/093G21K5/04A61N5/107A61N2005/1074A61N2005/1087A61N2005/1097H01J35/14
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Quick Facts
Patent No.
US 10,213,626
App. No.
15/152,479
Granted
Feb 26, 2019
Kind
B2
Abstract

The invention relates to a method and apparatus for control of a charged particle cancer therapy system. A treatment delivery control system is used to directly control multiple subsystems of the cancer therapy system without direct communication between selected subsystems, which enhances safety, simplifies quality assurance and quality control, and facilitates programming. For example, the treatment delivery control system directly controls one or more of: an imaging system, a positioning system, an injection system, a radio-frequency quadrupole system, a ring accelerator or synchrotron, an extraction system, a beam line, an irradiation nozzle, a gantry, a display system, a targeting system, and a verification system. Generally, the control system integrates subsystems and/or integrates output of one or more of the above described cancer therapy system elements with inputs of one or more of the above described cancer therapy system elements.

Claims (40)

1. An apparatus for treating a tumor of a patient using positively charged particles, comprising:

a positively charged particle tomography imaging system; and

a treatment delivery control system configured to control a plurality of sub-systems of a cancer therapy system, said plurality of sub-systems comprising:

an accelerator system;

an extraction system;

a beam transport line configured to transport the positively charged particles;

an irradiation nozzle; and

a gantry,

wherein a charged particle beam path sequentially passes through: at least part of an injector system, said accelerator system, said extraction system, said beam transport line, said irradiation nozzle, and at least part of said gantry,

wherein said tomography imaging system uses all of said accelerator system, said extraction system, said beam transport line, said irradiation nozzle; and said gantry, said tomography imaging system used to generate a proton tomography image of the tumor for use in subsequent treatment of the tumor using said cancer therapy system.

2. The apparatus of claim 1 , further comprising:

an X-ray imaging system, under control of said treatment delivery control system, configured to generate an X-ray image of the tumor during use, said X-ray image overlaid with a proton beam image generated using a proton beam imaging system to form a hybrid X-ray-proton beam image.

3. The apparatus of claim 1 , further comprising:

said treatment delivery control system configured to control an imaging system, said imaging system comprising: a beam position verification layer, responsive to passage of the positively charged particles, positioned between said irradiation nozzle and the patient during use; and

said beam position verification layer configured to indicate a location of the positively charged particles in said beam transport line between said irradiation nozzle and the patient during use.

4. The apparatus of claim 3 , further comprising:

a patient positioning system configured to hold the patient in an upright position during an image collection time period of using an X-ray imaging system and using said proton beam imaging system, the patient not moving from said patient positioning system during said image collection time period.

5. The apparatus of claim 3 , said treatment delivery control system further comprising:

control of multiple subsystems of said cancer therapy system without direct communication between said multiple subsystems, said multiple subsystems comprising all of: said accelerator system, said gantry, and an X-ray imaging system.

6. A method for treating a tumor of a patient using positively charged particles, comprising the steps of:

providing a positively charged particle tomography imaging system;

using a treatment delivery control system to control a plurality of sub-systems of a cancer therapy system, said plurality of sub-systems comprising:

an accelerator system;

an extraction system;

a beam transport line configured to transport the positively charged particles;

an irradiation nozzle; and

a gantry,

wherein a charged particle beam path sequentially passes through:

at least part of an injector system, said accelerator system, said extraction system, said beam transport line, said irradiation nozzle, and at least part of said gantry; and

said tomography imaging system using all of said accelerator system, said extraction system, said beam transport line, said irradiation nozzle; and said gantry to generate a proton tomography image of the tumor for use in subsequent treatment of the tumor using said cancer therapy system.

7. The method of claim 6 , further comprising the steps of:

generating a three-dimensional reference image of the patient using said positively charged particle tomography imaging system using four to hundreds of rotation positions of the patient relative to the positively charged particles; and

adapting a radiation treatment plan for the tumor using a two-dimensional control image, collected while the patient is in a treatment position, through comparison of the two-dimensional control image and the three-dimensional reference image.

8. The method of claim 6 , further comprising the steps of:

said treatment delivery control system controlling an imaging system; and

said imaging system determining a location of the positively charged particles in said beam transport line between said irradiation nozzle and the patient using a beam position verification layer positionally responsive to passage of the positively charged particles.

9. The method of claim 8 , further comprising the step of:

said treatment delivery control system controlling multiple subsystems of said cancer therapy system without direct communication between said multiple subsystems, said multiple subsystems comprising all of: said accelerator system and an X-ray imaging system.

10. The method of claim 6 , further comprising the step of:

replacing a specific subsystem of said plurality of subsystems controlled by said treatment delivery control system while only revising code to said specific subsystem.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 16, 2023
From: SPOTTS, STEPHEN L
To: PROTOM INTERNATIONAL HOLDING CORPORATION
Reel/Frame 062385/0289 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 29, 2021
From: BALAKIN, VLADIMIR
To: BALAKIN, ANDREY VLADIMIROVICH; BALAKIN, PAVEL VLADIMIROVICH
Reel/Frame 056711/0049 →
Continuity (17)
Continuation In Part 14216788 · Mar 17, 2014
Continuation In Part 13087096 · Apr 14, 2011
Continuation In Part 13788890 · Mar 7, 2013
Continuation In Part 15152479 · May 11, 2016
Continuation In Part 14952817 · Nov 25, 2015
Continuation In Part 14293861 · Jun 2, 2014
Continuation In Part 12985039 · Jan 5, 2011
Continuation In Part 15152479 · May 11, 2016
Continuation In Part 14860577 · Sep 21, 2015
Continuation 14223289 · Mar 24, 2014
Continuation In Part 14216788 · Mar 17, 2014
Continuation In Part 12985039 · Jan 5, 2011
Continuation In Part 15152479 · May 11, 2016
Continuation In Part 15073471 · Mar 17, 2016
Provisional Application 61324776 · Apr 16, 2010
Provisional Application 62304839 · Mar 7, 2016
Related Publication 20160250503A1 · Sep 1, 2016
Cited By (1)
US 12,245,355