IP Library Granted Patent US 9,644,170
Granted Patent B2
US 9,644,170 · App. 15/180,439 · Granted May 9, 2017

Bioeffective krill oil compositions

Inventors: Inge Bruheim (Volda, NO); Snorre Tilseth (Bergen, NO); Daniele Mancinelli (Orsta, NO)
Assignee: AKER BIOMARINE ANTARCTIC AS
C11B3/006A61K9/0053A61K9/48A61K9/4825A61K9/4858A61K31/122A61K31/20A61K31/202A61K31/23A61K31/235A61K31/683A61K31/685A61K35/612A61K45/06
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Quick Facts
Patent No.
US 9,644,170
App. No.
15/180,439
Granted
May 9, 2017
Kind
B2
Abstract

This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO 2 or CO 2 plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO 2 in combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.

Claims (20)

1. A krill oil composition comprising a capsule containing Euphausia superba krill oil suitable for oral administration, said krill oil comprising from 3% to 15% ether phospholipids w/w of said krill oil and astaxanthin esters in amount of greater than about 100 mg/kg of said krill oil.

2. The krill oil composition of claim 1 , wherein said krill oil composition is substantially odorless.

3. The krill oil composition of claim 1 , wherein said krill oil contains astaxanthin esters in an amount of greater than about 200 mg/kg of said krill oil.

4. The krill oil composition of claim 1 , wherein said krill oil comprises at least 30% total phospholipids w/w of said krill oil.

5. The krill oil composition of claim 1 , wherein said krill oil comprises at least 30% phosphatidylcholine w/w of said krill oil.

6. The krill oil composition of claim 1 , wherein said capsule contains a phytonutrient derived from a source other than krill.

7. The krill oil composition of claim 1 , wherein said krill oil further comprises from about 3% to about 10% w/w ether phospholipids; from about 27% to 50% w/w non-ether phospholipids so that the amount of total phospholipids in the composition is from about 30% to 60% w/w; and from about 20% to 50% w/w triglycerides.

8. The krill oil composition of claim 7 , wherein said krill oil further comprises from about 20% to 35% omega-3 fatty acids as a percentage of total fatty acids in said composition.

9. The krill oil composition of claim 1 , wherein said capsule is a soft gel capsule.

10. The krill oil composition of claim 1 , wherein said krill oil comprises less than about 0.45% w/w arachadonic acid.

11. A composition comprising a soft gel capsule containing Euphausia superba krill oil suitable for oral administration, said krill oil comprising from 3% to 15% ether phospholipids w/w of said krill oil and astaxanthin esters in amount of greater than about 100 mg/kg of said krill oil.

12. The composition of claim 11 , wherein said krill oil composition is substantially odorless.

13. The composition of claim 11 , wherein said krill oil contains astaxanthin esters in an amount of greater than about 200 mg/kg of said krill oil.

14. The composition of claim 11 , wherein said krill oil comprises at least 30% total phospholipids w/w of said krill oil.

15. The composition of claim 11 , wherein said krill oil comprises at least 30% phosphatidylcholine w/w of said krill oil.

16. The composition of claim 11 , wherein said krill oil comprises at least 40% phosphatidylcholine w/w of said krill oil.

17. The composition of claim 11 , wherein said capsule contains a phytonutrient derived from a source other than krill.

18. The composition of claim 11 , wherein said krill oil further comprises from about 3% to about 10% w/w ether phospholipids; from about 27% to 50% w/w non-ether phospholipids so that the amount of total phospholipids in the composition is from about 30% to 60% w/w; and from about 20% to 50% w/w triglycerides.

19. The composition of claim 18 , wherein said krill oil further comprises from about 20% to 35% omega-3 fatty acids as a percentage of total fatty acids in said composition.

20. The composition of claim 11 , wherein said krill oil comprises less than about 0.45% w/w arachadonic acid.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 8, 2024
From: AKER BIOMARINE ANTARCTIC AS
To: AKER BIOMARINE HUMAN INGREDIENTS AS
Reel/Frame 066703/0864 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 12, 2016
From: AKER BIOMARINE AS
To: AKER BIOMARINE ANTARCTIC AS
Reel/Frame 039421/0228 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 10, 2016
From: BRUHEIM, INGE; TILSETH, SNORRE; MANCINELLI, DANIELE
To: AKER BIOMARINE AS
Reel/Frame 039396/0844 →
Continuity (7)
Continuation 14020162 · Sep 6, 2013
Continuation 12057775 · Mar 28, 2008
Provisional Application 60920483 · Mar 28, 2007
Provisional Application 60975058 · Sep 25, 2007
Provisional Application 60983446 · Oct 29, 2007
Provisional Application 61024072 · Jan 28, 2008
Related Publication 20160279173A1 · Sep 29, 2016