IP Library Granted Patent US 9,962,291
Granted Patent B2
US 9,962,291 · App. 15/232,320 · Granted May 8, 2018

System and process for neuroprotective therapy for glaucoma

Inventors: Jeffrey K. Luttrull (Ojai, CA); Benjamin W. L. Margolis (Oakland, CA); David B. Chang (Tustin, CA)
Assignee: Ojai Retinal Technology, LLC
A61F9/00823A61F9/00821A61N5/0613A61B90/361A61F9/008A61F9/00817A61F2009/00844A61F2009/00863A61F2009/00891A61F2009/00897A61N2005/067
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Quick Facts
Patent No.
US 9,962,291
App. No.
15/232,320
Filed
Aug 9, 2016
Granted
May 8, 2018
Kind
B2
Art Unit
3769
USPC
606/6
Abstract

Providing neuroprotective therapy for glaucoma includes generating a micropulsed laser light beam having parameters and characteristics, including pulse length, power, and duty cycle, selected to create a therapeutic effect with no visible laser lesions or tissue damage to the retina. The laser light beam is applied to retinal and/or foveal tissue of an eye having glaucoma or a risk of glaucoma to create a therapeutic effect to the retinal and/or foveal tissue exposed to the laser light beam without destroying or permanently damaging the retinal and/or foveal tissue and improve function or condition of an optic nerve and/or retinal ganglion cells of the eye.

Claims (17)

1. A process for providing therapy for glaucoma, comprising the steps of:

generating a plurality of spaced apart pulsed laser light treatment beams, each having parameters to provide therapeutic effect to retinal tissue without permanently damaging the retinal tissue, wherein the parameters comprise an intensity of 100-590 watts per square centimeter, a pulse length of 500 milliseconds or less, a wavelength between 532 nm and 1300 nm and a duty cycle of 5% or less;

simultaneously applying the plurality of laser light treatment beams to a first treatment area of retinal tissue of an eye having glaucoma;

simultaneously reapplying the plurality of laser light treatment beams to the first treatment area after an interval of time during a single treatment session, wherein the interval of time is between 1 and 3 milliseconds; and

simultaneously applying the plurality of laser light treatment beams to a second treatment area of the retina spaced apart from the first treatment area during the interval of time, wherein the first treatment area or the second treatment area includes foveal tissue of the eye.

2. The process of claim 1 , including the step of controllably moving the plurality of laser light treatment beams and applying the laser light treatment beams to treat untreated retinal tissue until the entire retina of the eye is treated.

3. The process of claim 1 , wherein the plurality of laser light treatment beams are repeatedly applied to the first and second treatment areas until each of the first and second treatment areas receives 50 to 200 laser light applications.

4. The process of claim 3 , wherein each laser light application comprises a single pulse of laser light.

5. The process of claim 1 , wherein the first and second treatment areas are separated by at least a predetermined minimum distance to avoid thermal tissue damage.

6. The process of claim 1 , wherein the generating step comprises the step of generating the plurality of laser light beams from a plurality of pulsed lasers having different wavelengths.

7. The process of claim 1 , wherein the laser light is applied to the entire retina.

8. The process of claim 1 , wherein the first treatment area and the second treatment area are separated from each other by a minimum predetermined distance to avoid thermal damage to tissue of the first treatment area and the second treatment area; and

repeatedly applying the plurality of laser light treatment beams to the first and second treatment areas, until a predetermined number of laser light beam applications to the first treatment area and the second treatment area has been achieved; and

controllably moving the plurality of laser light treatment beams and simultaneously applying the plurality of laser light treatment beams to additional treatment areas until the entire retina, including the fovea, has been treated.

9. The process of claim 8 , wherein each of the treatment areas receives 50 to 200 laser light applications.

10. The process of claim 8 , wherein each laser light application comprises a single pulse of laser light.

11. The process of claim 8 , wherein the generating step comprises the step of generating the plurality of laser light beams from a plurality of pulsed lasers having different wavelengths.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 9, 2016
From: LUTTRULL, JEFFREY K.; MARGOLIS, BENJAMIN W. L.; CHANG, DAVID B.
To: OJAI RETINAL TECHNOLOGY, LLC
Reel/Frame 039386/0291 →
Continuity (12)
Continuation In Part 15148842 · May 6, 2016
Continuation In Part 14921890 · Oct 23, 2015
Continuation In Part 14607959 · Jan 28, 2015
Continuation In Part 13798523 · Mar 13, 2013
Continuation In Part 13481124 · May 25, 2012
Continuation In Part 15232320
Continuation In Part 15188608 · Jun 21, 2016
Continuation 13481124
Continuation 15232320
Continuation In Part 13798523
Continuation In Part 13481124
Related Publication 20160346126A1 · Dec 1, 2016