Method of preparing porous carbonate apatite from natural bone
A carbonate apatite prepared from natural bone. The carbonate apatite has a protein content of 2000-8000 parts per million and a surface area of 15 to 70 m 2 /g. Also provided is a method for preparing the carbonate apatite from cancellous bone particles.
1. A carbonate apatite prepared from natural bone, the carbonate apatite having a surface area of 15 to 70 m 2 /g and a protein content of 2000-8000 parts per million.
2. The carbonate apatite of claim 1 , wherein the carbonate apatite has a carbonate content of 1 to 7%.
3. The carbonate apatite of claim 2 , wherein the carbonate apatite has a degree of crystallinity of 45 to 65%.
4. The carbonate apatite of claim 1 , wherein the carbonate apatite has a degree of crystallinity of 45 to 65%.
5. A carbonate apatite prepared from natural bone by the steps consisting of:
providing cancellous bone particles;
treating the bone particles with hot water and an organic solvent;
repeating the treating step at least once;
drying the treated bone particles; and
heating the treated dried bone particles at 570° C. to 610° C. for 10 to 40 hours,
wherein the carbonate apatite has a surface area of 15 to 70 m 2 /g and a protein content of 2000-8000 parts per million.
6. The carbonate apatite of claim 5 , wherein the carbonate apatite has a carbonate content of 1 to 7%.
7. The carbonate apatite of claim 6 , wherein the carbonate apatite has a degree of crystallinity of 45 to 65%.
8. The carbonate apatite of claim 5 , wherein the carbonate apatite has a degree of crystallinity of 45 to 65%.
9. The carbonate apatite of claim 5 , wherein the organic solvent is isopropanol.
10. The carbonate apatite of claim 8 , wherein the organic solvent is isopropanol.
11. The carbonate apatite of claim 5 , wherein the temperature of the hot water is 80° C. to 100° C.
12. The carbonate apatite of claim 8 , wherein the temperature of the hot water is 80° C. to 100° C.
13. The carbonate apatite of claim 6 , wherein the organic solvent is isopropanol.
14. The carbonate apatite of claim 7 , wherein the organic solvent is isopropanol.
15. The carbonate apatite of claim 6 , wherein the temperature of the hot water is 80° C. to 100° C.
16. The carbonate apatite of claim 7 , wherein the temperature of the hot water is 80° C. to 100° C.