Dose measurement system and method
Embodiments described herein generally relate to devices, systems and methods for measuring the dose remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a plurality of light sources which are disposed and configured to emit electromagnetic radiation toward the container. A plurality of sensors are located in the apparatus that are optically coupleable to the plurality of light sources and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light sources. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors. The processing unit is further operable to convert the received data into a signature representative of the electromagnetic radiation detected by the plurality of sensors.
1. An apparatus for measuring a volume of liquid remaining in or dispensed from a drug delivery device, comprising:
a light source configured to emit electromagnetic radiation toward a portion of the drug delivery device, the electromagnetic radiation including a plurality of light rays;
a plurality of sensors optically coupleable to the light source, each sensor from the plurality of sensors configured to detect a portion of the plurality of light rays emitted by the light source; and
a processing unit configured to generate a signal signature representative of at least one of a transmitted portion, a refracted portion, and a reflected portion of the detected portion of the plurality of light rays.
2. The apparatus of claim 1 , wherein the light source is in a first medium having a first refractive index and the first medium is adjacent to a second medium having a second refractive index.
3. The apparatus of claim 2 , wherein the first medium is air and the second medium is liquid.
4. The apparatus of claim 2 , wherein the first medium adjoins the second medium on a first side of the second medium and on a second side of the second medium, the second side being opposite to the first side.
5. The apparatus of claim 4 , wherein:
a first light ray in the plurality of light rays incident on an interface of the first medium and the first side of the second medium penetrates through the second medium and transmits to the first medium adjoining the second side of the second medium;
a second light ray in the plurality of light rays incident on the interface of the first medium and the first side of the second medium refracts as it penetrates the second medium and reenters the first medium adjoining the second side of the second medium; and
a third light ray in the plurality of light rays incident on the interface of the first medium and the first side of the second medium reflects back into the first medium adjoining the first side of the second medium.
6. The apparatus of claim 5 , wherein the signal signature is representative of the transmitted portion of the first light ray, the refracted portion of the second light ray, and the reflected portion of the third light ray.
7. The apparatus of claim 5 , wherein a fourth ray in the plurality of light rays incident on the interface of the first medium and the first side of the second medium refracts in the second medium and reflects from a surface in the second medium back into the second medium and reenters the first medium adjoining the second side of the second medium.
8. The apparatus of 50 , wherein the signal signature is representative of the transmitted portion of the first light ray, the refracted portion of the second light ray, the reflected portion of the third light ray, and the reentered portion of the fourth light ray into the signal signature.
9. The apparatus of claim 1 , wherein the light source includes at least one wide angle light source.
10. The apparatus of claim 9 , wherein the at least one wide angle light source includes a plurality of adjacent wide angle light sources wherein at least a first portion of the electromagnetic radiation emitted by a first wide angle light source in the plurality of adjacent wide angle light sources overlaps with at least a second portion of the electromagnetic radiation emitted by a second wide angle light source in the plurality of adjacent wide angle light sources.
11. The apparatus of claim 1 , wherein the drug delivery device is an injection pen.
12. An apparatus for measuring a volume of liquid remaining in or dispensed from a drug delivery device, comprising:
a light source configured to emit electromagnetic radiation toward a portion of the drug delivery device, the electromagnetic radiation including a plurality of light rays;
a plurality of sensors optically coupleable to the light source and configured to detect a transmitted portion, a refracted portion, and a reflected portion of the plurality of light rays emitted by the light source; and
a processing unit configured to generate a signal signature representative of the transmitted portion, the refracted portion, and the reflected portion of the plurality of light rays detected by the plurality of sensors.
13. The apparatus of claim 12 , wherein the light source is in a first medium having a first refractive index and the first medium is adjacent to a second medium having a second refractive index.
14. The apparatus of claim 13 , wherein the first medium is air and the second medium is liquid.
15. The apparatus of claim 13 , wherein the first medium adjoins the second medium on a first side of the second medium and on a second side of the second medium, the second side being opposite to the first side.
16. The apparatus of claim 15 , wherein:
a first light ray in the plurality of light rays incident on an interface of the first medium and the first side of the second medium penetrates through the second medium and transmits to the first medium adjoining the second side of the second medium;
a second light ray in the plurality of light rays incident on the interface of the first medium and the first side of the second medium refracts as it penetrates the second medium and reenters the first medium adjoining the second side of the second medium; and
a third light ray in the plurality of light rays incident on the interface of the first medium and the first side of the second medium reflects back into the first medium adjoining the first side of the second medium.
17. The apparatus of claim 16 , wherein the signal signature is representative of the transmitted portion of the first light ray, the refracted portion of the second light ray, and the reflected portion of the third light ray.
18. The apparatus of claim 16 , wherein a fourth ray in the plurality of light rays incident on the interface of the first medium and the first side of the second medium refracts in the second medium and reflects from a surface in the second medium back into the second medium and reenters the first medium adjoining the second side of the second medium.
19. The apparatus of 71 , wherein the signal signature is representative of the transmitted portion of the first light ray, the refracted portion of the second light ray, the reflected portion of the third light ray, and the reentered portion of the fourth light ray into the signal signature.
20. The apparatus of claim 12 , wherein the drug delivery device is an injection pen.