IP Library › Granted Patent US 12,281,927
Granted Patent B2
US 12,281,927 · App. 18/731,813 · Granted Apr 22, 2025

Dose measurement system and method

Inventors: Richard Whalley (Cambridge, MA); James White (Cambridge, MA)
Assignee: Bigfoot Biomedical, Inc.
G01F22/00A61M5/16804A61M5/16886A61M5/1689G01F11/021G01F13/00G01F17/00G01F23/284A61M2005/3126A61M2205/3306A61M2205/3379A61M2205/70G01N21/1702
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Quick Facts
Patent No.
US 12,281,927
App. No.
18/731,813
Granted
Apr 22, 2025
Kind
B2
Abstract

Embodiments described herein generally relate to devices, systems and methods for measuring the dose remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a plurality of light sources which are disposed and configured to emit electromagnetic radiation toward the container. A plurality of sensors are located in the apparatus that are optically coupleable to the plurality of light sources and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light sources. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors. The processing unit is further operable to convert the received data into a signature representative of the electromagnetic radiation detected by the plurality of sensors.

Claims (43)

1. A method of operating a dose measurement system, comprising:

detecting a drug delivery device being coupled to the dose measurement system; and

scanning the drug delivery device in response to detecting the drug delivery device being coupled to the dose measurement system, the scanning of the drug delivery device including:

activating at least one light source to emit electromagnetic radiation towards the drug delivery device,

generating a signal signature representing the electromagnetic radiation detected by a plurality of sensors through the drug delivery device,

comparing the signal signature to reference signature to estimate a dose of a drug dispensed by the drug delivery device, and

in response to the estimated dose being greater than zero, storing the estimated dose in an onboard memory and operating the dose measurement system in a power save mode.

2. The method of claim 1 , further comprising:

operating in the power save mode in response to the estimated dose being zero.

3. The method of claim 1 , wherein in the power save mode, a communications module of the dose measurement system and electronics for the at least one light source and the plurality of sensors are turned off.

4. The method of claim 1 , wherein the dose measurement system remains in the power save mode for a predefined time.

5. The method of claim 1 , further comprising:

activating a communication module of the drug delivery device in response to detecting the drug delivery device is coupled to the dose measurement system.

6. The method of claim 1 , further comprising:

communicating dose data to an external device, the dose data including the estimated dose.

7. The method of claim 1 , wherein the detecting for the drug delivery device is via a detection mechanism of the dose measurement system.

8. The method of claim 1 , further comprising:

storing a time stamp for the estimated dose in the onboard memory along with the estimated dose.

9. The method of claim 1 , wherein the estimated dose is determined by determining a volume of the drug in the drug delivery device based on the signal signature and comparing the volume of the drug to a previously determined volume of the drug.

10. The method of claim 1 , wherein after the dose measurement system has been in the power save mode for the predefined time, activating a detection mechanism to repeat the detecting of a drug delivery device being coupled to the dose measurement system.

11. A dose measurement system, comprising:

a housing configured to receive at least a portion of a drug delivery device containing a drug;

at least one light source disposed and configured to emit electromagnetic radiation toward the drug delivery device;

a plurality of sensors optically coupleable to the at least one light source, each sensor of the plurality of sensors disposed and configured to detect the electromagnetic radiation emitted by the at least one light source; and

at least one processor disposed in the housing, the at least one processor configured to:

detect the drug delivery device being coupled to the housing,

scan the drug delivery device in response to detecting the drug delivery device being coupled to the dose measurement system, which includes:

activating the plurality of sensors to emit the electromagnetic radiation towards the drug delivery device,

receiving, from the plurality of sensors, data representing the electromagnetic radiation detected through the drug delivery device by the plurality of sensors,

generating a signal signature representing the electromagnetic radiation detected by the plurality of sensors through the drug delivery device,

comparing the signal signature to reference signature to estimate a dose of the drug delivered by the drug delivery device, and

in response to the estimated dose remaining being greater than zero, storing the estimated dose in an onboard memory and operating the dose measurement system in a power save mode.

12. The dose measurement system of claim 11 , wherein the at least one processor is further configured to operate the dose measurement system in the power save mode in response to the estimated dose being zero.

13. The dose measurement system of claim 11 , further comprising:

a communications module, wherein in the power save mode, the communications module of the dose measurement system and electronics for the at least one light source and the plurality of sensors are turned off.

14. The dose measurement system of claim 11 , further comprising:

a communication module, wherein the at least one processor is configured to activate the communication module in response to detecting the drug delivery device is coupled to the dose measurement system.

15. The dose measurement system of claim 14 , wherein the at least one processor is configured to communicate the dose data to an external device via the communication module.

16. The dose measurement system of claim 11 , wherein the dose measurement system remains in the power save mode for a predefined time.

17. The dose measurement system of claim 11 , further comprising:

a detection mechanism disposed in the housing, the at least one processor configured to detect the coupling of the drug delivery device to the housing via the detection mechanism.

18. The dose measurement system of claim 11 , wherein the at least one processor is further configured to store a time stamp for the estimated dose in the onboard memory along with the estimated dose.

19. The dose measurement system of claim 11 , wherein the estimated dose is determined by determining a volume of the drug in the drug delivery device based on the signal signature and comparing the volume of the drug to a previously determined volume of the drug stored in the onboard memory.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 28, 2025
From: WHALLEY, RICHARD; WHITE, JAMES
To: COMMON SENSING INC.
Reel/Frame 070958/0915 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 28, 2025
From: COMMON SENSING, INC.
To: BIGFOOT BIOMEDICAL, INC.
Reel/Frame 071086/0248 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 17, 2025
From: WHALLEY, RICHARD; WHITE, JAMES
To: COMMON SENSING INC.
Reel/Frame 069917/0028 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 17, 2025
From: COMMON SENSING, INC.
To: BIGFOOT BIOMEDICAL, INC.
Reel/Frame 069950/0882 →
Continuity (11)
Continuation 18160097 · Jan 26, 2023
Continuation 16861899 · Apr 29, 2020
Continuation 16235286 · Dec 28, 2018
Continuation 15464466 · Mar 21, 2017
Continuation 14982650 · Dec 29, 2015
Continuation 14548679 · Nov 20, 2014
Continuation PCTUS2013041982 · May 21, 2013
Continuation In Part 13796889 · Mar 12, 2013
Provisional Application 61754262 · Jan 18, 2013
Provisional Application 61649919 · May 21, 2012
Related Publication 20240318993A1 · Sep 26, 2024
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