IP Library › Granted Patent US 10,143,426
Granted Patent B2
US 10,143,426 · App. 15/486,704 · Granted Dec 4, 2018

Systems and methods for dynamically and intelligently monitoring a host's glycemic condition after an alert is triggered

Inventors: Hari Hampapuram (Portland, OR); Anna Leigh Davis (Cardiff by the Sea, CA); Naresh C. Bhavaraju (San Diego, CA); Apurv Ullas Kamath (San Diego, CA); Claudio Cobelli (Padua, IT); Giovanni Sparacino (Padua, IT); Andrea Facchinetti (Padua, IT); Chiara Zecchin (Pernumia, IT)
Assignee: DexCom, Inc.
A61B5/746A61B5/0004A61B5/0022A61B5/0031A61B5/14503A61B5/14532A61B5/4848A61B5/4866A61B5/7221A61B5/7275G06F19/00A61B5/002
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Quick Facts
Patent No.
US 10,143,426
App. No.
15/486,704
Granted
Dec 4, 2018
Kind
B2
Abstract

Systems and methods for providing sensitive and specific alarms indicative of glycemic condition are provided herein. In an embodiment, a method of processing sensor data by a continuous analyte sensor includes: evaluating sensor data using a first function to determine whether a real time glucose value meets a first threshold; evaluating sensor data using a second function to determine whether a predicted glucose value meets a second threshold; activating a hypoglycemic indicator if either the first threshold is met or if the second threshold is predicted to be met; and providing an output based on the activated hypoglycemic indicator.

Claims (22)

1. A method of avoiding unnecessary hyperglycemic alerts, the method comprising:

initially activating a first alert state based on one or more first criteria associated with a hyperglycemic condition;

waiting a time period before providing an output associated with the first alert state, wherein the waiting includes determining the time period using at least in part a machine or adaptive learning algorithm to learn a lag setting, unique to the individual, associated with the time period;

actively monitoring, by a processor module, data associated with the host's hyperglycemic condition during the waiting time period; and

providing an output associated with the first alert state after the waiting time period if the data associated with the host's hyperglycemic condition meets one or more second criteria and not providing an output associated with the first alert state after the waiting time period if the data associated with the host's hyperglycemic condition does not meet the one or more second criteria, wherein a numerical value associated with the one or more first criteria and a numerical value associated with the one or more second criteria are different.

2. The method of claim 1 , wherein the actively monitoring comprises determining an average glucose over a window of time.

3. The method of claim 1 , wherein the actively monitoring comprises determining an amplitude and/or direction of rate of change.

4. The method of claim 1 , wherein the actively monitoring comprises determining an amplitude and/or direction of rate of acceleration.

5. The method of claim 1 , wherein the actively monitoring comprises evaluating insulin information.

6. The method of claim 1 , wherein the actively monitoring comprises evaluating meal information or timing.

7. The method of claim 1 , wherein the waiting time period is user selectable.

8. The method of claim 1 , further comprising transitioning from the first alert state to an inactive alert state based on the data associated with the host's hyperglycemic condition meeting the one or more second criteria.

9. A system for processing data, the system comprising:

a continuous analyte sensor configured to be implanted within a body; and

sensor electronics configured to receive and process sensor data output by the sensor, the sensor electronics including a processor configured to:

initially activate a first alert state based on one or more first criteria associated with a hyperglycemic condition;

wait a time period before providing an output associated with the first alert state, wherein the waiting includes determining the time period using at least in part a machine or adaptive learning algorithm to learn a lag setting, unique to the individual associated with the time period;

actively monitor data associated with the host's hyperglycemic condition during the waiting time period; and

provide an output associated with the first alert state after the waiting time period if the data associated with the host's hyperglycemic condition meets one or more second criteria and not provide an output associated with the first alert state after the waiting time period if the data associated with the host's hyperglycemic condition does not meet the one or more second criteria, wherein a numerical value associated with the one or more first criteria and a numerical value associated with the one or more second criteria are different.

10. The system of claim 9 , wherein the actively monitoring comprises determining an average glucose over a window of time.

11. The system of claim 9 , wherein the actively monitoring comprises determining an amplitude and/or direction of rate of change.

12. The system of claim 9 , wherein the actively monitoring comprises determining an amplitude and/or direction of rate of acceleration.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 7, 2017
From: BHAVARAJU, NARESH C.; HAMPAPURAM, HARI; KAMATH, APURV ULLAS; RACK-GOMER, ANNA LEIGH
To: DEXCOM, INC.
Reel/Frame 044051/0899 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 7, 2017
From: COBELLI, CLAUDIO; FACCHINETTI, ANDREA; SPARACINO, GIOVANNI; ZECCHIN, CHIARA
To: UNIVERSITA DEGLI STUDI DI PADOVA
Reel/Frame 044052/0180 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 7, 2017
From: UNIVERSITA DEGLI STUDI DI PADOVA
To: DEXCOM, INC.
Reel/Frame 044052/0229 →
Continuity (5)
Continuation 14720668 · May 22, 2015
Continuation 13742841 · Jan 16, 2013
Continuation 13742694 · Jan 16, 2013
Provisional Application 61720286 · Oct 30, 2012
Related Publication 20170224291A1 · Aug 10, 2017
Cited By (1)
US 12,702,361