IP Library Granted Patent US 10,251,913
Granted Patent B2
US 10,251,913 · App. 15/527,804 · Granted Apr 9, 2019

Use of whey protein micelles and polysaccharides for improving insulin profile

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Quick Facts
Patent No.
US 10,251,913
App. No.
15/527,804
Granted
Apr 9, 2019
Kind
B2
Abstract

The present invention relates to a composition comprising polysaccharides and whey protein micelles for use in the treatment or prevention of a disorder linked to an increase in plasma postprandial insulin in a subject. The invention relates also to the non-therapeutic use of a composition comprising polysaccharides and whey protein micelles to decrease plasma postprandial insulin concentration. A further aspect of the invention is a process for forming polysaccharide-whey protein micelle complexes.

Claims (7)

1. A method for treating a disorder linked to an increase in plasma postprandial insulin in a subject in need of same, comprising administering to the subject a composition comprising polysaccharides and whey protein micelles, wherein the polysaccharides have a negative zeta potential at a pH value in the range of 2.5 to 4.5, wherein the weight ratio of the whey protein micelles to the polysaccharide is between 30:1 and 0.8:1, and wherein the whey protein micelles are obtainable by adjusting the pH of a whey protein aqueous solution to a value between 3.0 and 8.0 and subjecting the aqueous solution to a temperature between 80 and 98° C.

2. The method according to claim 1 wherein the disorder is selected from the group consisting of diabetes; impairment of glucose metabolism; hyperinsulinemia; and insulin resistance.

3. The method according to claim 1 wherein the subject is a diabetic or pre-diabetic patient.

4. The method according to claim 1 wherein the composition is a liquid composition comprising an aqueous dispersion of polysaccharides and whey protein micelles.

5. The method according to claim 4 , wherein the protein content of the composition is between 0.1 and 22 wt. % and wherein the composition is a heat treated composition.

6. The method according to claim 1 wherein the polysaccharides and whey protein micelles are in the form of polysaccharide-whey protein micelle complexes.

7. The method according to claim 1 wherein the composition is in the form of a beverage or yoghurt.

Assignments (5)
CORRECTIVE ASSIGNMENT TO CORRECT THE PATENT NUMBER 16062921 PREVIOUSLY RECORDED ON REEL 049391 FRAME 0756. ASSIGNOR(S) HEREBY CONFIRMS THE PATENT NUMBER SHOULD HAVE BEEN 16062912. Recorded Jul 3, 2020
From: NESTEC S.A.
To: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Reel/Frame 054082/0001 →
CORRECTIVE ASSIGNMENT TO CORRECT THE PATENT NUMBER 16062921 PREVIOUSLY RECORDED ON REEL 049391 FRAME 0756. ASSIGNOR(S) HEREBY CONFIRMS THE PATENT NUMBER SHOULD HAVE BEEN 16062912. Recorded Jul 3, 2020
From: NESTEC S.A.
To: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Reel/Frame 054082/0165 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ENGLISH TRANSLATION TO SHOW THE FULL AND CORRECT NEW NAME IN SECTION 51. PREVIOUSLY RECORDED AT REEL: 049391 FRAME: 0756. ASSIGNOR(S) HEREBY CONFIRMS THE MERGER. Recorded Jun 13, 2019
From: NESTEC S.A.
To: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Reel/Frame 049853/0398 →
MERGER Recorded Jun 6, 2019
From: NESTEC S.A.
To: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Reel/Frame 049391/0756 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 8, 2017
From: SCHMITT, CHRISTOPHE JOSEPH ETIENNE; POUTEAU, ETIENNE; POPA NITA, SIMINA FLORENTINA; DONATO-CAPEL, LAURENCE; BOVETTO, LIONEL JEAN RENE
To: NESTEC S.A.
Reel/Frame 043481/0062 →