IP Library › Granted Patent US 10,039,742
Granted Patent B2
US 10,039,742 · App. 15/581,558 · Granted Aug 7, 2018

Sn-2-monoacylglycerols and lipid malabsorption

Inventors: Bruce Bistrian (Ipswich, MA); Frederic Destaillats (Servion, CH); Cristina Cruz-Hernandez (Epalinges, CH); Fabiola Dionisi (Epalinges, CH); Isabelle Masserey-Elmelegy (Epalinges, CH); Manuel Oliveira (Chexbres, CH); Julie Celine Moulin (Attalens, CH)
Assignees: Nestec S.A.; Beth Israel Deaconess Medical Center, Inc.
A61K31/357A23K20/158A23L2/52A23L33/12A61K31/232A23V2002/00
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Quick Facts
Patent No.
US 10,039,742
App. No.
15/581,558
Granted
Aug 7, 2018
Kind
B2
Abstract

The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid maldigestion or malabsorption. One embodiment of the present invention relates to a composition comprising a sn-2 monoacylglycerol derivative, wherein the sn-1 and sn-3 positions are blocked by protective groups. The acyl group may be a fatty acid, for example one with anti-inflammatory properties.

Claims (5)

1. A composition comprising an sn-2 monoacylglycerol derivative selected from the group consisting of 1,3-diethyl-2-eicosapentaenoylglycerol, 1,3-dipropyl-2-eicosapentaenoylglycerol, a vanillin derivative of sn-2 monoeicosapentaenoylglycerol, and combinations thereof.

2. The composition of claim 1 , wherein the composition is selected from the group consisting of a food product, an animal food product, a pharmaceutical composition, a nutritional composition, a nutraceutical, a drink, a food additive and a medicament.

3. The composition of claim 1 , wherein the composition has a caloric density of 0.5 kcal/ml to 15 kcal/ml.

4. The composition of claim 1 , wherein the sn-2 monoacylglycerol derivative provides about 3% to 40% of the energy of the composition.

5. The composition of claim 1 , wherein the composition comprises a combination of sn-2 monoacylglycerol derivatives.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 18, 2020
From: RONGIONE, JOSEPH C.
To: STEPAN COMPANY
Reel/Frame 054410/0466 →
CORRECTIVE ASSIGNMENT TO CORRECT THE PATENT NUMBER 16062921 PREVIOUSLY RECORDED ON REEL 049391 FRAME 0756. ASSIGNOR(S) HEREBY CONFIRMS THE PATENT NUMBER SHOULD HAVE BEEN 16062912. Recorded Jul 3, 2020
From: NESTEC S.A.
To: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Reel/Frame 054082/0001 →
CORRECTIVE ASSIGNMENT TO CORRECT THE PATENT NUMBER 16062921 PREVIOUSLY RECORDED ON REEL 049391 FRAME 0756. ASSIGNOR(S) HEREBY CONFIRMS THE PATENT NUMBER SHOULD HAVE BEEN 16062912. Recorded Jul 3, 2020
From: NESTEC S.A.
To: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Reel/Frame 054082/0165 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ENGLISH TRANSLATION TO SHOW THE FULL AND CORRECT NEW NAME IN SECTION 51. PREVIOUSLY RECORDED AT REEL: 049391 FRAME: 0756. ASSIGNOR(S) HEREBY CONFIRMS THE MERGER. Recorded Jun 13, 2019
From: NESTEC S.A.
To: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Reel/Frame 049853/0398 →
MERGER Recorded Jun 6, 2019
From: NESTEC S.A.
To: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Reel/Frame 049391/0756 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 9, 2017
From: BISTRIAN, BRUCE; DESTAILLATS, FREDERIC; CRUZ-HERNANDEZ, CRISTINA; DIONISI, FABIOLA; MASSEREY-ELMELEGY, ISABELLE; OLIVEIRA, MANUEL; MOULIN, JULIE CELINE
To: NESTEC S.A.; BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
Reel/Frame 042301/0943 →
Priority Claims (1)
EP 10168420 · Jul 5, 2010 · regional
Continuity (5)
Division 15348334 · Nov 10, 2016
Division 14686340 · Apr 14, 2015
Division 14163163 · Jan 24, 2014
Division 13808779
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